Wonderful! Installing "libopenblas-base" and "libopenblas-dev" worked like a 
charm.

Thank you so much for your help, I would have never figured this out myself…

very best 

giuseppe

-- 
Giuseppe Pagnoni, PhD
Dip. Scienze Biomediche, Metaboliche e Neuroscienze
Sezione Fisiologia e Neuroscienze
Univ. di Modena e Reggio Emilia
Via Campi 287
I-41125 Modena, Italy
Tel: +39-059-205-5742
Fax: +39-059-205-5363

On Jun 7, 2013, at 1:52 PM, Dirk Eddelbuettel <[email protected]> wrote:

> 
> On 7 June 2013 at 11:01, Giuseppe Pagnoni wrote:
> | Dear all,
> | 
> | I am estimating a mixed-model in Ubuntu Raring (13.04� amd64), with the
> | code:
> | 
> | fm0 <- lme(rt ~ run + group * stim * cond,
> |                  random=list(
> |                    subj=pdSymm(~ 1 + run),
> |                    subj=pdSymm(~ 0 + stim)),
> |                  data=mydat1)
> | 
> | When I check the approximate variance-covariance matrix, I get:
> | 
> | > fm0$apVar
> | [1] "Non-positive definite approximate variance-covariance"
> 
> This comes from the BLAS / LAPACK libraries which you can switch in Debian /
> Ubuntu.  Eg I (currently) have both defaults and openblas installed:
> 
> edd@max:~$ COLUMNS=72 dpkg -l | grep -i "blas\|lapack"
> ii  libblas-dev    1.2.20110419 amd64        Basic Linear Algebra Subroutines 
> ii  libblas-test   1.2.20110419 amd64        Basic Linear Algebra Subroutines 
> ii  libblas3       1.2.20110419 amd64        Basic Linear Algebra Reference im
> ii  libblas3gf     1.2.20110419 all          Transitional package for libblas
> ii  liblapack-dev  3.4.2-1~exp3 amd64        Library of linear algebra routine
> ii  liblapack-pic  3.4.2-1~exp3 amd64        Library of linear algebra routine
> ii  liblapack3     3.4.2-1~exp3 amd64        Library of linear algebra routine
> ii  liblapack3gf   3.4.2-1~exp3 all          Transitional package for liblapac
> ii  libopenblas-ba 0.2.6-1~exp1 amd64        Optimized BLAS (linear algebra) l
> ii  libopenblas-de 0.2.6-1~exp1 amd64        Optimized BLAS (linear algebra) l
> edd@max:~$ 
> 
> The virtual package libblas is provided by the reference blas, atlas
> ("tuned") and openblas (multicore); similar for lapack.
> 
> edd@max:~$ apt-cache search libblas
> libblas-dev - Basic Linear Algebra Subroutines 3, static library
> libblas-doc - Basic Linear Algebra Subroutines 3, documentation
> libblas3 - Basic Linear Algebra Reference implementations, shared library
> libatlas-base-dev - Automatically Tuned Linear Algebra Software, generic 
> static
> libatlas3-base - Automatically Tuned Linear Algebra Software, generic shared
> libblas-test - Basic Linear Algebra Subroutines 3, testing programs
> libblas3gf - Transitional package for libblas
> libopenblas-base - Optimized BLAS (linear algebra) library based on GotoBLAS2
> libopenblas-dev - Optimized BLAS (linear algebra) library based on GotoBLAS2
> edd@max:~$ 
> 
> Try installing another package and see if that matters.  
> 
> The Windows and OS X versions of R will have used its internally packaged
> (not tuned, not multicore) BLAS/LAPACK. This can be changed there too; see
> the R Admin+Inst manual.
> 
> Dirk
> 
> | *However*, if I do the same on a Windows or a Mac OS X machine, I get:
> | 
> | > fm0$apVar
> |                reStruct.subj1 reStruct.subj2 reStruct.subj3 reStruct.subj1
> | reStruct.subj1   1.952757e-01   3.130089e-01   5.766955e-01  -0.1034862377
> | reStruct.subj2   3.130089e-01   5.703211e-01   9.864047e-01  -0.1937902915
> | reStruct.subj3   5.766955e-01   9.864047e-01   1.861434e+00  -0.3303689957
> | reStruct.subj1  -1.034862e-01  -1.937903e-01  -3.303690e-01   0.0941652375
> | reStruct.subj2  -3.464557e-03  -5.933008e-03  -1.102904e-02   0.0163847582
> | reStruct.subj3  -6.826057e-01  -1.186231e+00  -2.122872e+00   0.3705613715
> | lSigma          -2.058254e-06  -4.764783e-06   1.653583e-05  -0.0000146693
> |                reStruct.subj2 reStruct.subj3        lSigma
> | reStruct.subj1  -3.464557e-03  -6.826057e-01 -2.058254e-06
> | reStruct.subj2  -5.933008e-03  -1.186231e+00 -4.764783e-06
> | reStruct.subj3  -1.102904e-02  -2.122872e+00  1.653583e-05
> | reStruct.subj1   1.638476e-02   3.705614e-01 -1.466930e-05
> | reStruct.subj2   1.931738e-02  -2.020354e-02 -1.925015e-05
> | reStruct.subj3  -2.020354e-02   2.825301e+00  2.967063e-05
> | lSigma          -1.925015e-05   2.967063e-05  6.299813e-05
> | attr(,"Pars")
> | reStruct.subj1 reStruct.subj2 reStruct.subj3 reStruct.subj1 reStruct.subj2
> |       4.570267       4.299735       1.282732       4.859346       3.206102
> | reStruct.subj3         lSigma
> |      -2.631377       5.308304
> | attr(,"natural")
> | [1] TRUE
> | 
> | 
> | I am unable to figure out the reason why I get such a difference in the
> | output: all the machines are running the latest version of R (3.0.1) and
> | nlme package (3.1-109) as of today (updated from the CRAN master site).
> | 
> | Many thanks in advance for any suggestions,
> | 
> | best
> | 
> | -- 
> | Giuseppe Pagnoni
> | Dip. Scienze Biomediche, Metaboliche e Neuroscienze
> | Sezione Fisiologia e Neuroscienze
> | Univ. di Modena e Reggio Emilia
> | Via Campi 287
> | I-41125 Modena, Italy
> | Tel: +39-059-205-5742
> | Fax: +39-059-205-5363
> | 
> |     [[alternative HTML version deleted]]
> | 
> | 
> | ----------------------------------------------------------------------
> | _______________________________________________
> | R-SIG-Debian mailing list
> | [email protected]
> | https://stat.ethz.ch/mailman/listinfo/r-sig-debian
> 
> -- 
> Dirk Eddelbuettel | [email protected] | http://dirk.eddelbuettel.com


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