thank you.i will read the book.good wishes.






At 2013-09-10 18:00:02,r-sig-epi-requ...@r-project.org wrote:
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>Today's Topics:
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>   1. Re: R-sig-Epi Digest, Vol 68, Issue 1
>      (Pedro Emmanuel Alvarenga Americano do Brasil)
>
>
>----------------------------------------------------------------------
>
>Message: 1
>Date: Mon, 9 Sep 2013 09:32:37 -0300
>From: Pedro Emmanuel Alvarenga Americano do Brasil
>       <emmanuel.bra...@gmail.com>
>To: r-sig-epi@r-project.org
>Subject: Re: [R-sig-Epi] R-sig-Epi Digest, Vol 68, Issue 1
>Message-ID:
>       <CAFfGvyLTUX=du+nrpdqxettfn63evzpenhl9hxcec0sk2dv...@mail.gmail.com>
>Content-Type: text/plain
>
>Well,
>
>I assume you are using the rms package. Calibration through bootstrap can
>be conducted through the val.surv function. Penalizing degrees
>of freedom can be conducted with the pentrace function. Other way of
>calibration can also be conducted.
>
>I suggest you take a look at the book below. There are several examples of
>R codes.  Specially chapter 23.
>
> 1.
>Steyerberg EW. Clinical Prediction Models: A Practical Approach to
>Development, Validation, and Updating. 1o ed. Springer; 2008.
>
>Dr. Pedro Emmanuel A. A. do Brasil
>http://blog.ipec.fiocruz.br/lapclin-chagas/
>Curriculum Lattes:  http://lattes.cnpq.br/6597654894290806
>ResearchGate.net: https://www.researchgate.net/profile/Pedro_Brasil2/
>Instituto Nacional de Infectologia/Instituto de Pesquisa Clínica Evandro
>Chagas
>Fundação Oswaldo Cruz
>Rio de Janeiro - Brasil
>Av. Brasil 4365,
>CEP 21040-360,
>Tel 55 21 3865-9648
>e-mail: pedro.bra...@ipec.fiocruz.br
>e-mail: emmanuel.bra...@gmail.com
>
>---Apoio aos softwares livres
>www.zotero.org - gerenciamento de referências bibliográficas.
>www.broffice.org ou www.libreoffice.org - textos, planilhas ou
>apresentações.
>www.epidata.dk - entrada de dados.
>www.r-project.org - análise de dados.
>www.ubuntu.com - sistema operacional
>
>
>2013/9/4 <r-sig-epi-requ...@r-project.org>
>
>> Send R-sig-Epi mailing list submissions to
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>> Today's Topics:
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>>    1. help (???)
>>
>>
>> ----------------------------------------------------------------------
>>
>> Message: 1
>> Date: Wed, 4 Sep 2013 21:10:04 +0800 (CST)
>> From: ??? <06dongsh...@163.com>
>> To: r-sig-epi@r-project.org
>> Subject: [R-sig-Epi] help
>> Message-ID: <2b682ecc.208da.140e91815c7.coremail.06dongsh...@163.com>
>> Content-Type: text/plain; charset="gbk"
>>
>>
>>
>>
>>
>>
>>
>>
>>
>> hi, dear friend , i am dealing with a survival data for cancer. a variable
>> progression doesn't satisfy PH assumption, i have tried the paramatric
>> survival models, but they did not fit very well. at last ,i tried the
>> extension of Cox model with time-dependent variable, finding that the model
>> fit well with the smallest AIC, and the average or weight  HR is 1.6. when
>> progression occured in the first follow-up year, the HR was biggest ,and HR
>> gone down in the second year, like the picture showed. after having reading
>> over the examples in R help documents, i am not sure if i can plot
>>  nomogram for 5 year survival prediction. and cph may did not work well
>> when applied to  the Cox model with time-dependent variable,  i can use
>> coxph, set  " tt=function(x,t,...) {x *log(t)}"  as a alternative. but most
>> important, how can i complete the nomogram ,validate and calibrate.ie.setup
>> may help,but not show in detail.
>>        can you help me to plot a nomogram?  thanks for  reading.
>>
>>                                                                Dong
>> | |
>> | |
>> | |
>>
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