Hello all,
I was runing some analysis here and found an error with epitools::oddsratio.
First I tought it was in my data, later I tought I was running the function
incorrectly but I now realize that there is something with numbers close to
zero or cells with zero...
below the same error with a simulated data... but it happens exactly the
same with mine wich has one cell with 1.
> m<-matrix(c(360,7,0,120),byrow=F,nrow=2,ncol=2)
> m
[,1] [,2]
[1,] 360 0
[2,] 7 120
> oddsratio(m)
Erro em uniroot(function(or) { :
f() values at end points not of opposite sign
> m<-matrix(c(360,7,4,120),byrow=F,nrow=2,ncol=2)
> m
[,1] [,2]
[1,] 360 4
[2,] 7 120
> oddsratio(m)
Erro em uniroot(function(or) { :
f() values at end points not of opposite sign
> m<-matrix(c(360,7,7,120),byrow=F,nrow=2,ncol=2)
> m
[,1] [,2]
[1,] 360 7
[2,] 7 120
> oddsratio(m)
$data
Outcome
Predictor Disease1 Disease2 Total
Exposed1 360 7 367
Exposed2 7 120 127
Total 367 127 494
$measure
odds ratio with 95% C.I.
Predictor estimate lower upper
Exposed1 1.0000 NA NA
Exposed2 806.1128 300.7302 2560
$p.value
two-sided
Predictor midp.exact fisher.exact chi.square
Exposed1 NA NA NA
Exposed2 0 1.896808e-96 4.400778e-94
Is it impoossible to estimate OR confidence intervals with tables with very
low numbers? Any work around sugestions?
Abraço forte e que a força esteja com você,
Dr. Pedro Emmanuel A. A. do Brasil
Instituto de Pesquisa Clínica Evandro Chagas
Fundação Oswaldo Cruz
Rio de Janeiro - Brasil
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