Olà Mirian,

Are you using Poisson models with an offset? I've never tried this with the Epi package so giving us some sample code and sample data structure would help.

But if you simply use glm, one way to account for over-dispersion is by specifying family=quasipoisson. It maximizes the quasilikelihood rather than the likelihood (don't ask me the maths of this, maybe start with the Wikipedia...).

Another approach might be hierarchical modelling but we'd need to know your data structure.

Cheers.

David Evans
-----------------
Epidemiologist, Kappa Santé



Message: 1
Date: Wed, 19 May 2010 10:10:58 -0300
From: "Mirian Carvalho de Souza" <miria...@inca.gov.br>
To: <b...@steno.dk>
Cc: r-sig-epi@stat.math.ethz.ch, Mirian Gmail <mirianc...@gmail.com>
Subject: [R-sig-Epi] Age-period-cohort models for lung cancer
        mortality rates
Message-ID: <e587d8fa5fb8444ebc572547cafea...@inca.local>
Content-Type: text/plain; charset="iso-8859-1"

GeleiraHello!
I work at National Cancer Institute, Brazil and I'm interested on fit age-period-cohort models for lung cancer mortality rates. I'm using the Epi package, but I have a problem. There is over- dispersion on my data. How can I deal with this problem? Some one can suggest a solution?
Thanks
--
Mirian Carvalho de Souza
Instituto Nacional de C?ncer/MS

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