Suman,

Im sorry not to have a straight answer. I have never seen PLR used
specifically for development of prediction models. However, I could say that
there is many many examples around that show no consistent advantage of more
modern and complex methods over logistic regression, even if complex  non
linear relations among the predictors and the predictor towards the outcome
are suspected. Thus, you may want to consider other stuff such as software
availability and your own experience with a particular method. I suggest
these readings:


   1. D J Sargent, “Comparison of artificial neural networks with other
   statistical approaches: results from medical data sets,” Cancer 91, no. 8
   (April 15, 2001): 1636-1642.


   1. Peter C. Austin, “A comparison of regression trees, logistic
   regression, generalized additive models, and multivariate adaptive
   regression splines for predicting AMI mortality,” Statistics in
Medicine26, no. 15 (7, 2007): 2937-2957.

These readings will give the impression that the theories behind these
methods bring only theoretical advantages, but do not increase accuracy of
prediction when compared to logistic regression. Perhaps, if spend some time
to look more around, you may be able to find evidence against this
conclusion.

Kind regards and good luck with your PhD.

Abraço forte e que a força esteja com você,

Dr. Pedro Emmanuel A. A. do Brasil
Instituto de Pesquisa Clínica Evandro Chagas
Fundação Oswaldo Cruz
Rio de Janeiro - Brasil
Av. Brasil 4365
Tel 55 21 3865-9648
email: pedro.bra...@ipec.fiocruz.br
email: emmanuel.bra...@gmail.com

---Apoio aos softwares livres
www.zotero.org - gerenciamento de referências bibliográficas.
www.broffice.org ou www.openoffice.org - textos, planilhas ou apresentações.
www.epidata.dk - entrada de dados.
www.r-project.org - análise de dados.
www.ubuntu.com - sistema operacional


2010/10/27 <r-sig-epi-requ...@stat.math.ethz.ch>

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>   1. Kindly help me of applicability of PLSR method for        binary
>      outcome variable (Suman Kundu)
>
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> ----------------------------------------------------------------------
>
> Message: 1
> Date: Wed, 27 Oct 2010 01:48:52 -0700 (PDT)
> From: Suman Kundu <suman_m...@yahoo.com>
> To: r-sig-epi@stat.math.ethz.ch
> Subject: [R-sig-Epi] Kindly help me of applicability of PLSR method
>        for     binary outcome variable
> Message-ID: <874660.52882...@web112515.mail.gq1.yahoo.com>
> Content-Type: text/plain
>
> Dear friends,
>
> I am a PhD student at Erasmus Medical Centre, Rotterdam, The Netherlands. I
> found the R package "pls", which is very handy and useful. This package
> descibes how to use Partial Least Squares Regression (PLSR) and Principal
> Component Regression (PCR).
> Would you mind to kindly answer the following?
> Logistic regression (LR) is a commonly used method in medical science to
> make a prediction model for binary outcome variable. This is fine, and I
> would like to apply (if applicable) PLSR and PCR to construct a prediction
> model for binary outcome variable, and will check whether PLSR or PCR method
> helps to make better model compare to LR method, in the sence of
> discrimination and goodness-of-fit (calibration). However, I am not sure
> whether the R package "pls" allows to construct such a model.
> I will be pleased if you kindly let me know whether PLSR ( or PCR) method
> is applicable for binary outcome variable.
>
> Thank you very much for your suggestions.
>
> Kind regards,
> Suman Kundu
>
>
>
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