hello Paul
If you look at your fragments you see that in your decomposition you have
overlapping fragments:
set(['[3*]OCC(O[3*])C1CC1', '[4*]CC([4*])C1CC1', '[3*]Oc1ncncn1',
'[14*]c1ncncn1', '[3*]OCC([4*])C1CC1', '[3*]OC(C[4*])C1CC1',
'[3*]OC1CNC1', '[15*]C1CNC1'])
This indicated that the fragmentation did not go down to the smallest
fragments but stopped at a minimum fragment size of 2 to 4. You can seer
this from the fact that the ether oxygen is not included in the list. This
gives two options, either you set the argument or the default has changed.
The second one would probably be captured by a test so my guess is the
first one. if it's the second one I take the blame as Greg would never do
this.
Post your code if neither is the case.
Best
Peter
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