New 1.1 versions of htslib, samtools, and bcftools have been released.  These 
are minor bug-fix releases, and include the following notable fixes and new 
functionality compared to 1.0:

* Samtools fixmate and flagstat now consider supplementary reads
* Sorting BAM files with thousands of reference contigs now completes in a 
reasonable amount of time
* Fixed samtools idxstats when displaying statistics from indices generated by 
samtools 0.1.x
* Fixed samtools calmd memory leak
* Samtools fixmate now only adds a template cigar tag (ct:Z) when requested 
with -c, and never adds it repeatedly
* Regularised script #! directives as #!/usr/bin/env perl etc
* Fixed DPR annotation in samtools mpileup
* New bcftools convert and plugin commands and annotate --rename-chrs option
* BCFtools norm performance is improved and now averages QUALs and accumulates 
IDs and FILTERs
* Improved bcftools filter expressions, query support for IUPAC ambiguity 
codes, and annotate support for genotype fields
* Plugins for bcftools have now moved from annotate to the new plugin command

These releases can be found at <http://www.htslib.org/>.  Development and 
source code of these projects are linked from that web site and can be found in 
various Git repositories under <https://github.com/samtools>.  Updates to the 
htslib.org web site are ongoing.  In particular, we have recently added a 
sample CRAM workflow: see <http://www.htslib.org/workflow/#mapping_to_cram>.

Installing the tools will also install manual pages for them.  Once installed, 
you should be able to use "man bcftools" etc at your command line to find 
details of new commands and functionality.  Manual pages are also available 
online at <http://www.htslib.org/doc/> and these will soon be updated to 
reflect the 1.1 release.

    John

-- 
 The Wellcome Trust Sanger Institute is operated by Genome Research 
 Limited, a charity registered in England with number 1021457 and a 
 company registered in England with number 2742969, whose registered 
 office is 215 Euston Road, London, NW1 2BE. 

------------------------------------------------------------------------------
Meet PCI DSS 3.0 Compliance Requirements with EventLog Analyzer
Achieve PCI DSS 3.0 Compliant Status with Out-of-the-box PCI DSS Reports
Are you Audit-Ready for PCI DSS 3.0 Compliance? Download White paper
Comply to PCI DSS 3.0 Requirement 10 and 11.5 with EventLog Analyzer
http://pubads.g.doubleclick.net/gampad/clk?id=154622311&iu=/4140/ostg.clktrk
_______________________________________________
Samtools-help mailing list
Samtools-help@lists.sourceforge.net
https://lists.sourceforge.net/lists/listinfo/samtools-help

Reply via email to