On Wed, 8 Nov 2017, Susan Fairley wrote:

Thanks for letting me know about this.

I’ve had a (very) quick look and the samtools view -H command is working for me 
with v1.2.

[alignment]:samtools

Program: samtools (Tools for alignments in the SAM format)
Version: 1.2 (using htslib 1.2.1)


[alignment]:samtools view -H 
SC_GMFUL5306366.alt_bwamem_GRCh38DH.20151208.FULA.gambian_lowcov.cram
@HD     VN:1.5  SO:coordinate

Any thoughts on what is causing this and the best way to address it are welcome.

Is that the file on the FTP site, or a different copy? If it's a different copy, you need to upload it to the FTP site to replace the broken file. It would also be a good idea to check the rest for the similar problems.

Rob Davies              r...@sanger.ac.uk
The Sanger Institute    http://www.sanger.ac.uk/
Hinxton, Cambs.,        Tel. +44 (1223) 834244
CB10 1SA, U.K.          Fax. +44 (1223) 494919


--
The Wellcome Trust Sanger Institute is operated by Genome Research Limited, a charity registered in England with number 1021457 and a company registered in England with number 2742969, whose registered office is 215 Euston Road, London, NW1 2BE.
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