I did install before but after upgrading to high Sierra I am lacking some dev 
dependencies (Xcode is installed)
I tried installing xz using macport and got the error below (there is no port 
with -dev)

xz -V
xz (XZ Utils) 5.2.3
liblzma 5.2.3

I then found a post by schneidexe <https://github.com/schneidexe> 
https://github.com/sparklemotion/nokogiri/issues/1483 
<https://github.com/sparklemotion/nokogiri/issues/1483> to build zx from source 
and did it 

=> same error

I do not find a lilzma-dev for OSX 10.13.1 and do not use brew on my Mac 
(macport only)

Thanks for any suggestion

Stephane


> checking for BZ2_bzBuffToBuffCompress in -lbz2... yes
> checking for lzma.h... no
> checking for lzma_easy_buffer_encode in -llzma... yes
> configure: error: liblzma development files not found
> 
> The CRAM format may use LZMA2 compression, which is implemented in HTSlib
> by using compression routines from liblzma <http://tukaani.org/xz/>.
> 
> Building HTSlib requires liblzma development files to be installed on the
> build machine; you may need to ensure a package such as liblzma-dev (on Debian
> or Ubuntu Linux), xz-devel (on RPM-based Linux distributions or Cygwin), or
> xz (via Homebrew on macOS) is installed; or build XZ Utils from source.
> 
> Either configure with --disable-lzma (which will make some CRAM files
> produced elsewhere unreadable) or resolve this error to build HTSlib.
> configure: error: ./configure failed for htslib-1.6


 <http://www.nucleomics.be/>            Stephane Plaisance, Ph.D

Address: Herestraat 49, O&N4, Post Box 816, Room nr. 404-24 / 08.428, 3000 
Leuven - Belgium
Tel: +32 (0)16 37 31 26
Lync: +32 (0)16 32 00 60
Fax: +32 (0)16 37 31 29
Web: www.nucleomics.be <http://www.nucleomics.be/>
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