On Wed, Jul 05, 2023 at 03:11:50PM +0200, Adrian wrote:
> I noticed samtools works perfectly fine with gzip SAM and BAM files, but it
> does not work (to my knowledge) with gzip CRAM. Is there any reason for
> this? Is there any plan to implement support to gzip CRAM directly?

CRAM is already superior compression to gzip, so running gzip on the
CRAM will give minimal if any benefit.

James

-- 
James Bonfield (j...@sanger.ac.uk)
The Sanger Institute, Hinxton, Cambs, CB10 1SA


-- 
 The Wellcome Sanger Institute is operated by Genome Research 
 Limited, a charity registered in England with number 1021457 and a 
 company registered in England with number 2742969, whose registered 
 office is Wellcome Sanger Institute, Wellcome Genome Campus, 
 Hinxton, CB10 1SA.


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