Well, almost three years ago we had a GSoC student work on it… =P

Assuming you mean manual 3D segmentation, I second Greg’s recommendation of 
ITK-SNAP for fully manual segmentation. For semi-automated work, I recommend 
Ilastik (ilastik.org).

Juan.

On 5 Apr 2017, 7:43 PM -0400, Gregory Lee <grle...@gmail.com>, wrote:
>
> > > I was wondering if anyone on the list knew about software to do 3d 
> > > segmentation.
> > >
> > > Thanks
> > > Vighnesh
> > >
> >
> > A nice, free GUI-based tool for interactive 3D segmentation is itk-snap
> > http://www.itksnap.org/
> >
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