New treatment for severe eye disease found
ANIThursday, July 22, 2010 18:12 IST Email 
 
Washington, DC: Researchers may have found a new treatment for retinitis 
pigmentosa (RP), a severe neurodegenerative disease of the retina that 
ultimately results in blindness.


University of Massachusetts Medical School (UMMS) researcher Shalesh Kaushal, 
MD, PhD, chair of ophthalmology and associate professor of ophthalmology and 
cell biology and his team conducted the study.


Results from this study, in conjunction with prior in vitro data, suggest 
valproic acid may be an effective treatment for photoreceptor loss associated 
with RP.


Five of the seven patients in the study experienced improvement in their field 
of vision.


Because of its already known qualities as a potent inhibitor of the 
inflammatory response pathway and cell death, valproic acid was believed to 
have a unique profile making it a potential candidate as a retinal disease 
treatment.


"Repurposing drugs already approved by the FDA and which have been shown to be 
safe, such as valproic acid, is an economical and time-efficient way to quickly 
bring new treatments to patients," said Kaushal.


The study is published in the July 20 online edition of the British Journal of 
Ophthalmology.

http://www.dnaindia.com/health/report_new-treatment-for-severe-eye-disease-found_1413160

Vikas Kapoor,
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