Re: AIDS/POLIO-Not Much Econ

2000-09-21 Thread Robin Hanson

William T. Dickens wrote:
> >The article did grant that there
> >remains the strange puzzle of the coincidence in timing of the various
> >strands of AIDS all being transmitted from primates to humans within a
> >close period, which I suppose that Hooper will emphasize when backed
> >into a corner.  The article suggests theories of population increases
> >or the introduction of cheap syringes, both of which might explain why
> >infection didn't happen earlier.
>
>I'm probably way in over my head here, but I thought that there was still 
>a lot of controversy over exactly when and where AIDS first emerged in the 
>human population. I seem to remember hearing it claimed that there were 
>confirmed cases in humans before the polio vaccination campaign. I thought 
>I've also heard it claimed that the wave of reports around the time of the 
>vaccine could be explained by a reporting anomaly -- that there was a buzz 
>in the medical community that caused people to recognize what they were 
>seeing as a single disease whereas before that time the pattern of 
>symptoms might not have been seen as a unique disease.  -- Bill

I'm admittedly in over my head as well, but it seems clear that there are 
several
distinct strands of AIDS, which all seem to have been in humans since near the
start of the epidemic.  And since it is unlikely that a single primate or human
was infected with more than one of these strands, there have to have been
multiple transmission events from primates to humans.  The issue isn't about
reports of when people said they saw the disease, but about what we can now 
infer
about who had what when.


Robin Hanson  [EMAIL PROTECTED]  http://hanson.gmu.edu
Asst. Prof. Economics, George Mason University
MSN 1D3, Carow Hall, Fairfax VA 22030-
703-993-2326  FAX: 703-993-2323



Re: AIDS/POLIO-Not Much Econ

2000-09-21 Thread William Dickens

> The article did grant that there
>remains the strange puzzle of the coincidence in timing of the various
>strands of AIDS all being transmitted from primates to humans within a
>close period, which I suppose that Hooper will emphasize when backed
>into a corner.  The article suggests theories of population increases
>or the introduction of cheap syringes, both of which might explain why
>infection didn't happen earlier.  

I'm probably way in over my head here, but I thought that there was still a lot of 
controversy over exactly when and where AIDS first emerged in the human population. I 
seem to remember hearing it claimed that there were confirmed cases in humans before 
the polio vaccination campaign. I thought I've also heard it claimed that the wave of 
reports around the time of the vaccine could be explained by a reporting anomaly -- 
that there was a buzz in the medical community that caused people to recognize what 
they were seeing as a single disease whereas before that time the pattern of symptoms 
might not have been seen as a unique disease.  -- Bill Dickens


William T. Dickens
The Brookings Institution
1775 Massachusetts Avenue, NW
Washington, DC 20036
Phone: (202) 797-6113
FAX: (202) 797-6181
E-MAIL: [EMAIL PROTECTED]
AOL IM: wtdickens




Re: AIDS/POLIO-Not Much Econ

2000-09-21 Thread Robin Hanson

Alexander Tabarrok wrote:
>...  Furthermore as Robin pointed out
>there was "a claimed strong correlation between where CHAT was given and
>the earliest HIV cases. But this correlation is only described via some
>maps.  This cries out for a more formal statistical analysis..."
>According to the Economist (Sept. 16, 2000) a "closer analysis" (don't
>know if this is the same as Robin's formal analysis) suggests that the
>correlation is spurious.

Yes, I saw that and was curious to know whether the analysis critical
is any better than Hooper's analysis.  The article did grant that there
remains the strange puzzle of the coincidence in timing of the various
strands of AIDS all being transmitted from primates to humans within a
close period, which I suppose that Hooper will emphasize when backed
into a corner.  The article suggests theories of population increases
or the introduction of cheap syringes, both of which might explain why
infection didn't happen earlier.  But I'm not sure they can explain why
we haven't seen more such transmissions since then.

Robin Hanson  [EMAIL PROTECTED]  http://hanson.gmu.edu
Asst. Prof. Economics, George Mason University
MSN 1D3, Carow Hall, Fairfax VA 22030-
703-993-2326  FAX: 703-993-2323



AIDS/POLIO-Not Much Econ

2000-09-20 Thread Alex Tabarrok

  List regulars may recall a side discussion that occurred some time ago
on the possibility that polio vaccination loosed the AIDS epidemic on
the world.  As Robin pointed out the case is made in a big book by
Edward Hooper.  As I mentioned then, some samples of the oral polio
vaccine from original batches in the late 1950's still existed.  They
have just recently been tested by three separate and independent
laboratories and shown to be HIV free.  Furthermore as Robin pointed out
there was "a claimed strong correlation between where CHAT was given and
the earliest HIV cases. But this correlation is only described via some
maps.  This cries out for a more formal statistical analysis..." 
According to the Economist (Sept. 16, 2000) a "closer analysis" (don't
know if this is the same as Robin's formal analysis) suggests that the
correlation is spurious.

Thought you would want to know.

Alex

---
Dr. Alexander Tabarrok
Vice President and Director of Research
The Independent Institute
100 Swan Way
Oakland, CA, 94621-1428
Tel. 510-632-1366, FAX: 510-568-6040
Email: [EMAIL PROTECTED]