>Mustard Musings
>
>I'm starting the New Year in a new way. I'm auditing the opening classes
>of
>the new school in town, The Tai Sophia Institute of Herbal Healing,
>offering
>a Master's Degree therein. Got back in town from Peru in time to attend
>a
>potluck dinner welcoming the new faculty and the first crop of ten
>promising
>students. I brought my vegetarian lentil soup, described in an earlier
>lentil newletters.  I almost always add a dash of several of the pungent
>
>spices to most of my soups, black pepper, capsicum, garlic, ginger,
>mustard,
>onion, and turmeric, in a sense making many of the antiarthrtic
>phytochemicals including the COX-2- inhibitor curcumin more readily
>available. Yes, now that I am no longer employed by the Herb Industry, I
>am leaning more and more towards food farmacy, at the same time as the
>press is scaring the pants off the public with frightening stories of
>herb/drug
>interactions. They fail to tell us that herbs kill fewer than 100
>Americans
>a year (usually those who are abusing the herb) while prescribed
>pharmaceuticals kill more than 100,000 Americans a year. And they fail
>to
>tell us, as did NBC TV News Jan 29, 2002, that 9 million Americans,
>including one of the President's close relatives, are abusing
>prescription
>pharmaceuticals.
>I'm auditing these classes because I am very keen that this first
>Master's
>Degree Program in Herbal Healing  succeed. I'm auditing so that when my
>classes come up, I can relate my lectures to the lectures the students
>have
>already heard or will be hearing, from such luminaries as 7-Song,
>Soaring
>Bear, Kerry Bone, Steve Dentali, Mary Enig, Kathe Koumoutsias,
>Jacqueline Krikorian, Kathleen Maier, Simon Mills, Rachel Pritzker,
>Aviva Romm,  Lynn Schumake, James Snow,  Kevin Spellman, Claudia Wingo,
>David Winston, and Tom Wolfe. It's been a great pleasure listening to
>Simon Mills pivotal openings lectures on the Six Tastes, in which he
>first covered the pungent compounds,which have triggered this issue of
>my newsletter.
>In their book, Principles and Practice of Phytotherapy, used as a text
>in
>the Tai Sophia Program, Mills and Bone (2000) note that most, if not
>all,
>members of the mustard family contain glucosinolates (sulfur and
>nitrogen-containing compounds, which though not pungent in themselves
>are
>responsible for the pungency). When a glucosinolate comes in contact
>with
>the enzyme myrosinase, located in different parts of the cells of most
>mustyard relatives, the glucosiniolate is enzymatically converted into
>the
>pungent (and corrosive) isothiocyanate. Mustard compresses are still
>widely
>used in Europe for bronchial troubles and chronic inflammatory diseases.
>The mucolytic activities of the hot compounds could be useful in many
>inflammatory conditions.  Glucosinolates and/or their breakdown products
>
>have long been known for their  allelopathic, bactericidal, fungicidal,
>and
>nematicidal properties and lately cancer chemoprevention:
>GLUCOSINOLATE: \Anticancer PC56:5; \Antiseptic PC56:5; Antithyroid
>NIG;\Bactericide PC56:5; \Chemopreventive PC56:5; \Fungicide PC56:5;
>\Nematicide PC56:5;
>
>And here's what my database says about isothiocyanates, not surprising
>since the glucosinolates, when enzymatically altered by myrosinase, form
>
>isothiocyanates:
>
>*ISOTHIOCYANATE: Anticancer PC56:5; Antiseptic MAB; Antithyroid NIG;
>Antitumor MAB; Bactericide MAB; Chemopreventive MAB; Fungicide MAB;
>Hypotensive; Goitrogenic MAB; 450- Inhibitor X11506821 ; Mucolytic MAB;
>\Nematicide PC56:5;   Respiradepressant; LD50=120
>
>Most interesting to me in Mill's lecture was his description of a
>British
>mustard handbath for digital arthritis or arthritis of the hand. Simply
>put
>some dry powered mustard into a pan of hot water. Then immerse your
>hands for a few minute. Deep penetrating action detoxifies, apparently.
>It's
>certainly worth a try. How well I remember my mothers last ten years.
>Both
>of her hands were almost locked uinto the curved position by what I
>assume
>was arthritis. And every time my hands lock up due to too much garden
>work, I fear that I'll suffer the same fate. But, taking command, I get
>on my
>exercise bike, get those dumbells, peddling as I exercise the very
>muscles
>that are tending to cramp up. I believe the rheumatologists when they
>say
>that one of the best things for arthritis is exercise. And if I find
>them
>locking up on me rheumatically, I may use some powdered mustard in a
>handbath. Or maybe I'll cook up a big batch of mustard greens, with
>black
>pepper, capsaicin, curry, garlic, and onion, and drink half the
>potlikker
>and steep my hands in the other half. (making it even more potent by
>psiking
>with horseradish or wasabi..
>But now, let me warn you, as Simon Mill skillfully warned his audience.
>Appropriately used, these can be very good phytomedicines. But overdo
>it,
>and you're in trouble. These compounds are corrosive and will cause
>blisters
>(sometimes desired by some healers, if not their patients). And while
>normal
>doses will prevent cancer, this does not mean that you should eat
>broccoli,
>cabbage, cauliflower, collards, horseradish, kohlrabi, mustard greens,
>radish, wasabi, watercress,  etc, by the ton. Almost all cancer
>preventive
>compounds can actually aggravate cancer in unreasonably high doses, say
>10 to 100 times the chemopreventive dose. And yes, too much can mess up
>your thyroid, even cause goiter, while a little is good.
>Here I go again, repeating myself too frequently: all things in
>moderation,
>except perhaps variety. Eat some mustard greens, some cabbage, come
>broccoli, especially those that you enjoy.  But I advise my friends
>against
>taking up a monofood diet, like mustard greens or broccoli, or cabbage,
>eating tons of that one boring crucifer every day. It ain't natural. Eat
>a
>natural diet, closer to what our ancestors ate, with  a wide variety of
>blue, green, orange, purple, red and yellow fruits and vegetables, a
>wide
>variety, I repeat.. Enjoy a few 100 g servings of various crucifers each
>
>week. I'm convinced it will help prevent cancer, as will moderate doses
>of
>members of the garlic family (chives, garlic, leek, onion, ramp). Mix
>and
>match. Good diet and good exercise and positive thinking may be your
>best
>allies against cancer and other major maladies, cardiopathy, diabetes
>and
>several of the the other big killers, like pharmaceuticals. The better
>your
>diet, execise, and stress control, the less likely you are to need
>pharmaceuticals, one of the top ten killers of North Americans.
>
>Here's what I said about mustard in my Medicinal Plants of the Bible
>
>                            BRASSICA NIGRA (L.) Koch
>Black Mustard
>
>...The kingdom of heaven is like to a grain of mustard seed, which a man
>
>took, and sowed in his field: Which indeed is the least of all seeds:
>but
>when it is grown, it is the greatest among herbs...Matthew 13
>
>Black mustard is cultivated for its seeds, the source of commercial
>table
>mustard, used as a condiment and medicine. Seeds also contain both a
>fixed
>and an essential oil, used as a condiment, lubricant, and soap
>constituent.
>Black mustard is mixed with while mustard (Sinapis alba) to make mustard
>
>flour, used in various condiments as "English Mustard" when mixed with
>water and "Continental Mustard" with vinegar. The leaves are eaten as a
>potherb. Mustard flowers are good honey producers. In agriculture
>mustard is also used as a cover crop. Smoke from burning mustard is said
>to repel flies and mosquitoes (Kirtikar & Basu, 1975).
>Mustard is considered anodyne, apertif, carminative, diuretic, emetic,
>laxative, rubefacient, stimulant, stomachic, and vesicant (Duke & Wain,
>1981). Mustard plaster is used externally for many afflictions, like
>arthritis and rheumatism. A liquid prepared from the seed, when gargled,
>is
>said to be a folk remedy for tumors of the "sinax". In Ethiopia alone,
>the
>seed is used for amebiasis, abscesses, bloat, constipation, dysentery,
>rheumatism, and stomachache as well as for abortion (Jansen, 1981). A
>decoction or plaster of the seed used in a cataplasm is used for
>hardness of
>the liver and spleen. Seeds are also said to help carcinoma and throat
>tumors. Lately mustards have been shown to contain at least five
>compounds
>which inhibit neoplasias induced by polycyclic aromatic hydrocarbons.
>Mustard relieves congestion by drawing the blood to the surface as in
>head
>afflictions, neuralgia, spasms. Hot water poured on bruised seeds makes
>a
>stimulant foot bath, good for colds and headaches. Old herbals suggested
>
>mustard for alopecia, epilepsy, snakebite, and toothache. Mustard oil is
>
>said to stimulate hair growth. Mustard is also recommended as an
>aperient
>ingredient of tea, useful in hiccup. Mustard flour is considered
>antiseptic.
>The oil is considered useful in pleurisy and pneumonia. Ayurvedics value
>the
>leaves for throat complaints and worms,  the  seeds  for cough,
>external
>parasites,  fever,  itch, megalospleny skin ailments, tumors, and worms.
>
>Unani also recommend the seeds for boils, ear, eye and nose problems,
>edema, inflammation, rheumatism and toothache (Kirtikar & Basu, 1975).
>(Duke & Duke, 1983)
>
>Wow, it's already ground hog day. Feb. 2, 2002. I have crocus,
>dandelion,
>hellebores, periwinkle, and snowdrop are already in flower. Its been a
>gentle winter, breaking records near 80oF Feb. 1.  Groundhogs will be
>coming up (dare I say germinating) with the first of the wild mustard
>seeds. I
>suspect the groundhogs, wthther or not they see their shadow,  will take
>a
>few bites of wild mustard sprouts and then move on, not overdosing on
>any
>one pungent species. Like my deer, they avoid the wild mustard species
>heavily laden with the pungent defensive compounds that prevent cancer.
>And like my deer, the groundhogs are more likely, like humans, to eat
>the less bitter, less pungent cultivated relatives, broccoli, cabbage,
>etc., which
>are not any longer so well endowed with those pungent compounds that
>deter the feeding of the bugs (and bacteria and fungi) as well as the
>mammals. Up in West Virginia, my son's country consorts eat the
>groundhog. I hope they have serve it with a mess of wild mustard greens,
>to complement that greasy groundhog. Too much tame meat, (less so wild
>game like groundhog), can up your chances of many of those same diseases
>the cabbage and onion relatives will prevent. Happy Ground Hog Day.
>
>And here's a pretty good array of what will show up in edition 2 of my
>CRC
>Handbook of Medicinal Herbs, due out later this year.
>  BLACK MUSTARD (Brassica nigra (L.) W. D. J. Koch ++
>
>Note: Many writers to not distinguish between black, brown (Indian), and
>
>white mustard(Brassica nigra, Brassica juncea and Sinapis alba
>respectively)
>but the spice and medicine trade seems to favor the white. And the
>canola
>and rapeseed varieties have been hopelessly manipulated, even in the GMO
>
>field. Few if any taxonomists and agronomists can distinguish all
>Brassica
>varieties and species, and probably fewer chemists, herbalists,
>pharmacists,
>and physicians can be sure of the variety or species. My entries can be
>no
>more reliable than their sources. Seems as though the group might better
>be
>treated generically than specifically or varietally.
>ACTIVITIES (BLACK MUSTARD): Abortifacient (f; CEB; DAW);  Anodyne (f;
>DAW);
>Antidote (Narcotics) (f; CEB; FEL); Antifertility (f; WOI); Carminative
>(f;
>DAW); Diuretic (f; DAW; fel; HHB); Emetic (f; DAW); Gastrotonic (f;
>CEB);
>Laxative (f; DAW); Orexigenic (f; DAW); Pancreatonic (f; CEB);
>Rubefacient
>(f; DAW);, Stimulant  (f; DAW; WOI); Stomachic (f; DAW; HHB; WOI);
>Vesicant
>(f; DAW);
>
>INDICATIONS (BLACK MUSTARD): Abscess (f; DAW); Adenopathy (f; JLH); Ague
>(f;
>DEM); Alopecia (f; DAW); Ameba (f; DAW); Amenorrhea (f; FEL); Angina (f;
>
>FEL; HHB);  Anorexia (f; DAW; DEM); Apoplexy (f; FEL); \Arthrosis (1;
>FNF);
>htAsthma (f; DEM); Bite (f; CEB); Bloat (f; DAW); Boil (f; DAW);
>Bronchosis
>(f; HHB; PH2); Cancer (1; FNF: JLH);   Cancer, colon (1; FNF: JLH);
>Cancer,
>liver (1; FNF: JLH); Cancer, neck (1; FNF; JLH); Cancer, sinew (1; FNF:
>JLH);   Cancer, skin (1; FNF: JLH); Cancer, spleen (1; FNF: JLH);
>Cancer,
>throat (1; FNF; JLH);Cancer, uterus (1; FNF: JLH);  Cancer, wrist (1;
>FNF:
>JLH); Cardiopathy (f; HHB; PH2); Cholera (f; FEL); Circulosis (f; PH2);
>Cold
>(f; DAW; DEM); Congestion (f; DAW; FEL); Constipation (f; DAW; FEL);
>Cough
>(f; DAW); Cramp (f; DAW); CVI (f; PH2); Dermatosis (f; DAW); Dysentery
>(f;
>DAW); Dysmenorrhea (f; FEL); Dyspepsia (f; CEB; FEL); Ectoparasite (f;
>DAW);
>Edema (f; DAW); Enterosis (f; FEL; PH2); Epilepsy (f; DAW); Fever (f;
>DAW);
>Fever (f; DEM; FEL; HHB); Fibroid (f; JLH); Fibroma (f; JLH); Gastrosis
>(f;
>FEL; PH2); Glaucoma (f; PH2); Headache (f; DAW; FEL;  PH2); Headcold (f;
>
>DEM);  Heartburn (f; HHB); Hepatosis (f; JLH); Hiccups (f; DAW);
>Induration
>(f; JLH); Inflammation (f; DAW; FEL); Itch (f; DAW); Lumbago (f; PH2);
>Lymphoma (f; JLH); Meningosis (f; FEL); Nervousness (f; DEM); Neuralgia
>(f;
>DAW; WOI); Ophthalmia (f; DAW); Otosis (f; DAW); Pain (f; DEM; FEL;
>HHB);
>Pharyngosis (f; DAW); Phthisis (f; DEM); Pleurisy (f; DAW; FEL; PH2;
>WOI);
>Polyp (f; JLH);  Pneumonia (f; DAW; PH2; WOI); Pulmonosis (f; FEL);
>Respirosis (f; PH2); Rheumatism  (1; DAW; FNF; PH2; WOI); Rhinosis (f;
>DAW);
>Sciatica (f; PH2); Sclerosis (f; JLH); Sinusosis (f; PH2); Snakebite (f;
>
>DAW); Splenosis (f; DAW); Spine (f; FEL); Stomachache (f; DAW); Sore
>Throat
>(f; DAW); Toothache (f; CEB; DAW; DEM); Tuberculosis (f; DEM); Typhus
>(f;
>FEL); Uterosis (f; JLH); Worm (f; DAW);
>
>
>CONTRAINDICATIONS, INTERACTIONS, AND SIDE EFFECTS (BLACK MUSTARD): Class
>1
>(Internal, Ingestion of too much can be irritating); Class 2b (External;
>
>duration not to exceed two weeks; not for children under 6 yrs. Severe
>burns may occur with longterm topical use. (AHP). Counterindications:
>children younger than 6 years; renal disease (mustard oil is absorbed
>through the skin). Even external poultice should be limited to 5-10 mins
>pediatrically,
>10-15 min for adults, less for sensitive patients. (KOM); [Millspaugh
>has
>said "unground seeds. . .proved dangerous, as they are liable to become
>impacted in the bowel and set up a fatal inflammation.] (CEB)., 15-30
>min/s
>plaster can cause severe burns (AHP). Adverse effects: skin and nervous
>damage (prolonged use). Should not be used for more than 2 weeks (AEHD).
>
>Avoid taking with ammonia-containing products as ammonia with mustard
>oil
>yields inactive thiosinamine. (PH2); Contraindicated in GI ulcers and
>nephrosis (PHR) Overdoses internally cause GI distress. (PHR)
>Hyperthyroidism with goiter traced "to the use of the isothiocyanates in
>
>mustard." (APA); Delaneyite nitpickologists will doubtless clamber to
>put
>the same goitrogenic warning on all members of the mustard family as
>well as
>papaya, caper and nasturtium.
>
>BRASSICA NIGRA (L.) Koch
>"BLACK MUSTARD"
>ALLYL-CYANIDE  SD HHB
>\ALLYLGLUCOSINOLATES   10,000-50,000 PL PH2
>ALLYL-ISOTHIOCYANATE  6,510-11,760 SD WOI
>ALLYL-RHODANIDE  SD HHB
>ARGININE  1,810-26,657 LF USA
>ASCORBIC-ACID  234-4,013 LF USA
>ASH  50,000-54,112 SD WOI
>ASH  5,830-99,722 LF USA
>CAFFEIC-ACID  SD CRC(FNS)
>CALCIUM  1,107-17,867 LF USA
>CARBOHYDRATES  192,000-207,792 SD WOI
>CARBOHYDRATES  34,100-502,209 LF USA
>BETA-CAROTENE  29-475 LF USA
>CHLOROGENIC-ACID  SD CRC(FNS)
>TRANS-CINNAMIC-ACID  SD CRC(FNS)
>COPPER  0.58-11.2 LF USA
>P-COUMARIC-ACID  SD CRC(FNS)
>CYSTINE  370-5,449 LF USA
>EO  7,000-12,000 SD WOI
>ERUCIC-ACID  770-11,340 LF USA
>\FAT  282,000-350,000  SD WOI PH2
>FAT  2,220-46,841 LF USA
>FERULIC-ACID  SD CRC(FNS)
>FIBER  110,000-119,048 SD WOI
>FIBER  8,000-117,820 LF USA
>GADOLEIC-ACID  260-3,829 LF USA
>GLUCONAPIN  PL JBH
>GLUCONASTURTIIN  PL JBH
>GLUCOPUTRANJIVIN  SD JBH
>HISTIDINE  450-6,627 LF USA
>HYDROXYBENZOIC-ACID  SD CRC(FNS)
>IRON  12-209 LF USA
>ISOLEUCINE  910-13,402 LF USA
>ISOPROPYL-ISOTHIOCYANATE  PL JBH
>KILOCALORIES  200-2,946 LF USA
>LEUCINE  760-11,192 LF USA
>LINOLEIC-ACID  270-3,976 LF USA
>ALPHA-LINOLENIC-ACID  240-3,535 LF USA
>LYSINE  1,130-16,642 LF USA
>MAGNESIUM  132-2,471 LF USA
>MANGANESE  3-53 LF USA
>MESOINOSITOL-HEXAPHOSPHORIC-ACID-ESTER  SD HHB
>METHIONINE  230-3,387 LF USA
>MUCILAGE  200,000 SD HHB
>MYROSIN  6,800 SD WOI
>NIACIN  3.03-47.87 LF USA
>NONACOSANE  LF JBH
>OLEIC-ACID  200-2,945 LF USA
>PALMITIC-ACID  60-884 LF USA
>PALMITOLEIC-ACID  10-147 LF USA
>PANTOTHENIC-ACID  0.19-2.79 LF USA
>PHENYLALANINE  660-9,720 LF USA
>2-PHENYLETHYL-ISOTHIOCYANATE  SD JBH
>PHOSPHORUS  290-4,563 LF USA
>@PHYLLOQUINONE  0.565-3.39 FL JN126:1183S
>POTASSIUM  1,485-28,215 LF USA
>PROGOITRIN  PL JBH
>PROTEIN  23,650-385,190 LF USA
>\PROTEIN 400,000 SD PH2
>PROTOCATECHUIC-ACID  SD CRC(FNS)
>RIBOFLAVIN  0.56-9.72 LF USA
>SINAPIC-ACID  SD CRC(FNS)
>\SINAPINE  10,000 SD BIS PH2
>SINAPINE  SD CCO JBH
>@SINIGRIN  10,000-12,000 SD BIS PH2
>SODIUM  274-4,506 LF USA
>STEARIC-ACID  20-294 LF USA
>THIAMIN  0.44-7.66 LF USA
>THREONINE  660-9,720 LF USA
>TRYPTOPHAN  270-3,976 LF USA
>TYROSINE  1,320-19,440 LF USA
>VALINE  970-14,286 LF USA
>VANILLIC-ACID  SD CRC(FNS)
>WATER  76,000 SD WOI
>WATER  930,030-933,900 LF USA
>ZINC  2-40 LF USA
>
>James A. "Jim" Duke
>Botanical Consultant
>Herbal Vineyard, Inc.
>8210 Murphy Road
>Fulton, MD  20759
>Ph.:  301-498-1175
>Fax:  301-498-5738
>E-mail:  [EMAIL PROTECTED]
>
>For Medical Botany Syllabus, with many modules, see:
>http://www.ars-grin.gov/duke/syllabus
>For example, there is an Herbal Desk Reference (HDR) Module, with
>bioactivities, indications, some dosage levels, and counterindications
>and
>side effects.
>
>For  newsletter, see:  http://www.fathernaturesfarmacy.com

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