Forwarded in plain text for Andrea: Hi Esther,
>I'm very curious why this product has NO published >study on male kittens/cats. Also, I cannot find where >FDA approved for neutersol's use on male cats/kittens. > >In shelters, cats are just as big an overpopulation >problem as dogs, if not worse.So I'm very interested >to learn why they chose dogs and omitted cats from >both their study and from FDA's approval. I asked a >Phd involved w/animal studies and he suggests that >dogs are sometimes chosen because they will tolerate >medications that cats will not. I have not thought much about the cat issue, but did think of a few things. I suspect that before the company did all the research and spent $$$ for the research and FDA process, they wanted to see if the concept would work on dogs and see if the shelters would embrace using the drug. I suspect that dogs initially were chosen because they can be much easier to handle for the people dealing with administering and following these dogs, dogs have larger testicles so easier to be able to feel for changes in the testicle and monitor for other reactions, semen collection was needed to verify sterility (never seen semen collected from a cat!), and I thought of another reason but now can't recall what it was. I did hear a vet lecturer at the vet conference this past January explain the cat/dog drug thing. Not only do cats metabolize a drug differently than dogs do, each cat metabolizes it differently from the next cat (I assume this means that most dogs metabolize the same drug the same way). This is one reason why it has been so very hard for drug companies to produce an effective pain reliever in cats. If the cats all metabolize it differently how can you figure out what dose would be effective and safe for what cat? Cheers, Andrea
