[L3] RE: SCOUTED: Are Americans part of an UnregulatedExperiment?_USA Today

2003-07-15 Thread Deborah Harrell
Here's one I apparently meant to send some time ago-

--- Chad Cooper [EMAIL PROTECTED] wrote:
massive snippage 

 This article shows that good reaserch is needed more
 than arbetrary bans on chemicals and technology.
 
 Environmental pollution, pesticides, and the
 prevention of cancer:
 misconceptions [published erratum appears in FASEB J
 1997 Dec;11(14):1330]   BN Ames and LS Gold 
 Department of Molecular and Cell Biology, University
 of California, 94720,
 USA. [EMAIL PROTECTED] 
 
 The major causes of cancer are: 1) smoking, which
 accounts for about a third
 of U.S. cancer and 90% of lung cancer; 2) dietary
 imbalances: lack of
 sufficient amounts of dietary fruits and vegetables.
 The quarter of the
 population eating the fewest fruits and vegetables
 has double the cancer
 rate for most types of cancer than the quarter
 eating the most; 3) chronic
 infections, mostly in developing countries; and 4)
 hormonal factors, influenced primarily by lifestyle.

I'll add that viruses (like human papilloma virus)
contribute as well, althopugh maybe they were putting
them in the chronic infection category.
 
 There is no cancer epidemic except for
 cancer of the lung due to smoking. Cancer mortality
 rates have declined by
 16% since 1950 (excluding lung cancer).

I'm not sure where they got those figures; CDC data
tables comparing cancer deaths per 100,000 population
in various decades beginning with 1950 actually show a
slight increase: all ages/all persons 1950 = 193.9
deaths per 100K; 1998 = 202.4.  At ages 55-64 there is
a 'breakover' with younger people having less
mortality now than in 1950, and older people having
increased mortality (but the population is also
proportionately older) now.  However, female cancer
mortality is down overall (I suspect that is due to
improved detection/treatment of breast and cervical
cancers), while male cancer mortality is up
(especially black male, but black female is up too).
http://www.cdc.gov/nchs/data/hus/tables/2002/02hus039.pdf

Certainly lung cancer deaths have increased since
1950, especially in the over-65 set:
http://www.cdc.gov/nchs/data/hus/tables/2002/02hus040.pdf

Five-year cancer survival rates have improved more in
men than women, although lung rates have been fairly
stable, with a slight gain in survival for white
males, and loss for black females.  (Annoyingly,
breast was not listed in this table.)
http://www.cdc.gov/nchs/data/hus/tables/2002/02hus057.pdf

[OK, I had to check: while white females have seen a
mild decline in breast cancer mortality, black females
have had an increase in it -- health care access
issues?  So much for my theory about the decline in
overall female cancer mortality; maybe women eat more
fruits and veggies, especially the older ones??]
http://www.cdc.gov/nchs/data/hus/tables/2002/02hus041.pdf

 Regulatory policy that focuses on
 traces of synthetic chemicals is based on
 misconceptions about animal cancer
 tests. Recent research indicates that rodent
 carcinogens are not rare. Half
 of all chemicals tested in standard high-dose animal
 cancer tests, whether
 occurring naturally or produced synthetically, are
 carcinogens; there are
 high- dose effects in rodent cancer tests that are
 not relevant to low-dose
 human exposures and which contribute to the high
 proportion of chemicals
 that test positive...Plants in the human diet
 contain thousands of
 natural pesticides produced by plants to protect
 themselves from insects
 and other predators: 63 have been tested and 35 are
 rodent carcinogens...The focus of regulatory policy
 is on synthetic
 chemicals, although 99.9% of the chemicals humans
 ingest are natural.

Wild animals, including humans, evolved along with
these plants; susceptible individuals are likely to
have died or had fewer offspring.  An example of an
artificial chemical which our bodies apparently do not
handle well is trans-fatty acids, which come from
artificial hydrogenation of oils (promotes heart
disease; there was a recent ruling that foods are
going to have to be labeled with the grams of
trans-fats/serving -- some snack foods companies have
already removed hydrogenated products from their chips
etc.).

 There is no convincing evidence that synthetic
 chemical pollutants are
 important as a cause of human cancer.

But there is plenty of evidence that specific
chemicals cause various conditions, including cancer,
especially with occupational exposure:
arsenic = skin and lung cancer
benzene = various leukemias  lymphomas
polychlorinated biphenyls = reproductive damage,
liver damage, chloracne (chronic skin rash/breakdown),
and probably skin cancer

This 1998 study finds exposure to certain herbicides
and fungicides increases risk for non-Hodgkin's
lymphoma, which has been increasing in Western
societies:
http://www.poptel.org.uk/panap/archives/nhl.htm
...In this study, exposure to both herbicides and
fungicides resulted in significantly increased risks
for NHL. Among herbicides, the phenoxyacetic 

Re: [L3] RE: SCOUTED: Are Americans part of an UnregulatedExperiment?_USA Today

2003-07-15 Thread Jan Coffey

--- Deborah Harrell [EMAIL PROTECTED] wrote:
 Here's one I apparently meant to send some time ago-

Very thurough. Thank you for sharing all that work.

=
_
   Jan William Coffey
_

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