Re: Nutty Conspiracist [was: [L3] RE: Bird flu movie]

2006-05-12 Thread Deborah Harrell
 Alberto Monteiro [EMAIL PROTECTED] wrote:
 Deborah Harrell quoted:

  They found that a genetic mutation that gives its
 carriers 
  protection against the HIV virus became relatively
 common among 
  white Europeans about 700 years ago
 
 paranoid
 So the HIV virus was designed by White People to
 kill Black People!
 THEY had convinced me that it had been fnord
 designed by Hetero People 
 to kill Gay People. Time to chance Conspiracy
 Theories!
 /paranoid

totally ridiculous
Only in retaliation for BPs throwing pale persons out
of Africa, thus forcing them to marry each other, and
produce offspring ever more susceptible to the
too-powerful yet life-giving rays of the sun; the
result is those dour Norwegians who live in darkness
nearly half the year, leading to a high suicide rate.
or possibly ludicrous

Debbi
Metastasizing Melanoma Maru

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Re: Nutty Conspiracist [was: [L3] RE: Bird flu movie]

2006-05-12 Thread Deborah Harrell
 Deborah Harrell [EMAIL PROTECTED] wrote:

snip
 or possibly ludicrous

eyeroll
I forgot the wicked smiley!;-}

Debbi
Bird Flu Is A Ploy Of The Gubru Maru

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Re: Nutty Conspiracist [was: [L3] RE: Bird flu movie]

2006-05-12 Thread Julia Thompson

Deborah Harrell wrote:

Deborah Harrell [EMAIL PROTECTED] wrote:


snip

or possibly ludicrous


eyeroll
I forgot the wicked smiley!;-}

Debbi
Bird Flu Is A Ploy Of The Gubru Maru


That would have hit the monitor if I'd been drinking anything here.  One 
of the most amusing things I've read today.  (Maybe THE most amusing thing.)


Julia
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Nutty Conspiracist [was: [L3] RE: Bird flu movie]

2006-05-11 Thread Alberto Monteiro
Deborah Harrell quoted:

 They found that a genetic mutation that gives its carriers 
 protection against the HIV virus became relatively common among 
 white Europeans about 700 years ago

paranoid
So the HIV virus was designed by White People to kill Black People!
THEY had convinced me that it had been fnord designed by Hetero People 
to kill Gay People. Time to chance Conspiracy Theories!
/paranoid

Alberto Monteiro

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Re: Nutty Conspiracist [was: [L3] RE: Bird flu movie]

2006-05-11 Thread Klaus Stock
  They found that a genetic mutation that gives its carriers 
  protection against the HIV virus became relatively common among 
  white Europeans about 700 years ago
 
 paranoid
 So the HIV virus was designed by White People to kill Black People!
 THEY had convinced me that it had been fnord designed by Hetero People 
 to kill Gay People. Time to chance Conspiracy Theories!
 /paranoid

Don't make fun of this...I know that you are one of them...

...I noticed the suspicous space before the word designed. If you know
where to look...


- Klaus ;-)

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RE: Bird flu movie

2006-05-10 Thread Dan Minette


 -Original Message-
 From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On
 Behalf Of Deborah Harrell
 Sent: Wednesday, May 10, 2006 4:13 PM
 To: brin-l@mccmedia.com
 Subject: Bird flu movie
 
 The acting was bad, the plot had some major holes,
 some of the science was more-than-iffy - but it was
 interesting to watch, and if it made people think
 ahead just a little bit, that might actually be
 helpful:
 
 http://www.webmd.com/content/article/121/114487.htm
 ...ABC's Fatal Contact: Bird Flu in America is
 fiction. It presents a worst-of-worst-cases scenario
 of what might happen in a pandemic of deadly, highly
 contagious bird flu.
 
 Could what happens in the movie really take place?
 Laurie Garrett, senior fellow for global health at the
 Council of Foreign Relations, was a script consultant
 for the movie (at her request, her name does not
 appear in the movie credits). She's seen an advance
 screening.
 
 The film is very grim. But I don't think it is
 sensationalistic, Garrett tells WebMD. I didn't
 think they exaggerated, but it is a worst-case
 scenario. A virulent, highly contagious flu comes to
 America. There is no viable vaccine on tap. The drugs
 have limited or no efficacy. There are shortages of
 essential supplies and goods that become acute later
 in the epidemic...
 
 Debbi
 who has ~ 2 weeks worth of food on-hand, and could
 probably hold out for 4 if necessary (but would likely
 end up working at a temp hospital if a true pandemic occurred)

I didn't see the movie but did see the ABC nightline on the facts.  I was
also in this debate before, and have looked up some facts.

They had some of the real life counterparts of people in the movie (the
secretary of HHS and the governor of Virginia, as well as CDC scientists on
Nightline.  The most criticized part of the show was the end, when the
second wave of the flu killed 100%.  The CDC scientist said while nothing
was impossible in biology, this was very very unlikely.  That makes sense.
If such things happened once every 100,000 years, the odds on humans still
being here would be rather low.

If the 1918 flu epidemic is the template for the next one, then the death
rates are vastly overstated.  In some countries, the death rate approached
10%.  But, in the US it was less than 1%...0.6% IIRC.  I'd argue that the
state of medicine and nutrition had a lot to do with the difference.
Further, we'd probably lose fewer people now than we did then for the same
type of pandemic because:

1) We have better nutrition and general health.  Few are starving in the US.
2) We don't have rampant TB.  If you look at the TB deaths in the years
following the flu, they dropped noticeably.  One argument was that the flu
resulted in an early harvest of TB deaths of people who appeared fairly
healthy but had TB.
3) We are much better prepared to fight bacterial pneumonia, etc. than we
were before 1920.
4) We do have some Tamiflu.by 2008 it will be enough to dose an expected
25% infection rate.  

Given this, it's probable that the death rate from a pandemic that's the
equivalent of the Spanish flu would be lower.  I'd guess to the 0.25% level
or so.

It's harder to speculate on worse flu's, but if the exponential tail rule
for pandemics works like the symptoms rule (30% get sick, 4% get very sick
but only 0.6% died), then a death rate of 1% would require a once in a
millennium flu or worse.

It doesn't mean that it won't be a problem.  Our standards for governmental
response to a crisis is much higher than it was in the early 20th century,
and I'd expect the response to fall short.  Even if we have a US full of New
Orleans, we should not expect a 1% death rate.

Dan M.


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[L3] RE: Bird flu movie

2006-05-10 Thread Deborah Harrell
Oh, bloody h-
I just lost my entire reply to this - now attempting
to reconstruct it.  mutters dire imprecations...all
those sites! All that time!

 Dan Minette [EMAIL PROTECTED] wrote:
  Behalf Of Deborah Harrell

  The acting was bad, the plot had some major holes,
  some of the science was more-than-iffy - but it
 was
  interesting to watch, and if it made people think
  ahead just a little bit, that might actually be
  helpful:
 
 http://www.webmd.com/content/article/121/114487.htm

 I didn't see the movie but did see the ABC nightline
 on the facts.  I was
 also in this debate before, and have looked up some
 facts.
 
 They had some of the real life counterparts of
 people in the movie (the
 secretary of HHS and the governor of Virginia, as
 well as CDC scientists on
 Nightline.  The most criticized part of the show was
 the end, when the
 second wave of the flu killed 100%.  The CDC
 scientist said while nothing
 was impossible in biology, this was very very
 unlikely.  That makes sense.

Even Ebola isn't that deadly.

 If such things happened once every 100,000 years,
 the odds on humans still being here would be rather 
low.

But that may be what happened to cheetahs - see *
below (and darnit I was right about the virus being
~12K years ago still very vexed). Also see **, which
I may have posted before, about a theory that a viral
infection in the Scandanavian area may have conferred
resistance to the Black Death (which may not have just
been plague bacillus), and perhaps to HIV. (I was
incorrect about that being 10K years ago; it's more
like 2500-5K years ago.)
 
 If the 1918 flu epidemic is the template for the
 next one, then the death
 rates are vastly overstated.  In some countries, the
 death rate approached
 10%.  But, in the US it was less than 1%...0.6%
 IIRC.  I'd argue that the
 state of medicine and nutrition had a lot to do with
 the difference.

From Wiki:
http://en.wikipedia.org/wiki/Spanish_Flu
...Global mortality rate from the flu is estimated at
2.5% – 5% of the human population, with 20% of the
world population suffering from the disease to some
extent. It spread across the world killing 25 million
in six months; some estimates put the total killed at
over twice that number, possibly even 100 million.

An estimated 17 million died in India, about 5% of
India's population at the time. In the Indian Army,
almost 22% of troops who caught the disease died of
it. In US, about 28% of the population suffered, and
500,000 to 675,000 died. In Britain 200,000 died; in
France more than 400,000. The death rate was
especially high for indigenous peoples; entire
villages perished in Alaska and southern Africa. In
the Fiji Islands, 14% of population died during only
two weeks, and in Western Samoa 22%. In Japan, 257,363
deaths were attributed to influenza by July 1919,
giving an estimated 0.425% mortality rate...

From  http://www.stanford.edu/group/virus/uda/
...The effect of the influenza epidemic was so severe
that the average life span in the US was depressed by
10 years. [I saw 12 years on another site.]  The
influenza virus had a profound virulence, with a
mortality rate at 2.5% compared to the previous
influenza epidemics, which were less than 0.1%. The
death rate for 15 to 34-year-olds of influenza and
pneumonia were 20 times higher in 1918 than in
previous years (Taubenberger). People were struck with
illness on the street and died rapid deaths. One
anectode shared of 1918 was of four women playing
bridge together late into the night. Overnight, three
of the women died from influenza (Hoagg)...
...With one-quarter of the US and one-fifth of the
world infected with the influenza, it was impossible
to escape from the illness. Even President Woodrow
Wilson suffered from the flu in early 1919 while
negotiating the crucial treaty of Versailles to end
the World War (Tice)...

From the CDC [detailed article; has links to most of
the footnoted articles, also lots of graphs]:
http://www.cdc.gov/ncidod/eid/vol12no01/05-0979.htm
...An estimated one third of the world's population
(or #8776;500 million persons) were infected and had
clinically apparent illnesses (1,2) during the
1918–1919 influenza pandemic. The disease was
exceptionally severe. Case-fatality rates were 2.5%,
compared to 0.1% in other influenza pandemics (3,4).
Total deaths were estimated at #8776;50 million (5–7)
and were arguably as high as 100 million (7).

The impact of this pandemic was not limited to
1918–1919. All influenza A pandemics since that time,
and indeed almost all cases of influenza A worldwide
(excepting human infections from avian viruses such as
H5N1 and H7N7), have been caused by descendants of the
1918 virus, including drifted H1N1 viruses and
reassorted H2N2 and H3N2 viruses. The latter are
composed of key genes from the 1918 virus, updated by
subsequently incorporated avian influenza genes that
code for novel surface proteins, making the 1918 virus
indeed the mother of all pandemics...With the
appearance 

RE: Bird flu vaccine contract

2005-09-20 Thread Horn, John
 Behalf Of Deborah Harrell
 Government studies conducted at the
 National Institutes of Health (NIH) concluded that two
 90-microgram doses of the vaccine were needed to
 produce an effective immune response in humans. That
 dose is more than 12 times higher than the single
 15-microgram dose usually needed for protection from
 seasonal flu.
 
 The NIH is conducting more studies to determine how
 much the vaccine can be diluted while retaining its
 effectiveness, or what amount of other vaccine
 ingredients used to boost effectiveness will be
 required.
 
 Until the studies arecomplete, company officials won't
 know how many vaccine doses will be available or what
 the final price per dose will be...

Or what the side effects will be.  I know that I always feel like
hell the day after getting a flu shot and my arm hurts for a few
days.  What would a 12x higher level dose do?

 - jmh
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Re: One Flu over the Cookoo's Nest

2004-10-21 Thread Keith Henson
At 10:57 PM 20/10/04 -0700, Doug wrote:
They could, of course, salvage the whole lot by treating it with radiation.
Keith
Think the shortage of flu vaccine is just bad luck?
http://www.washingtonpost.com/wp-dyn/articles/A18795-2004Oct8.html
Britain: U.S. Told Of Vaccine Shortage
LONDON, Oct. 8 -- British health officials said Friday that their American 
counterparts were informed in mid-September that problems at a drug 
manufacturing plant in northwest England could disrupt influenza vaccine 
supplies to the United States.

And to fully understand how the vaccine problem was yet another leadership 
failure by the Bush administration check the conclusion and 
reccomendations starting on page 22 of this  GAO report 
(PDF)http://aging.senate.gov/events/hr67gao.pdf compiled in 2001 and 
entitled FLU VACCINE: Supply Problems Heighten Need to Ensure Access for 
High-Risk People.

--
Doug
Time he flu the coop.
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Re: One Flu over the Cookoo's Nest

2004-10-21 Thread JDG
At 10:57 PM 10/20/2004 -0700 Doug Pensinger wrote:
Think the shortage of flu vaccine is just bad luck?

Lately many liberals have suggested that the US government should use its
buying power to try and drive down prescription drug prices and lower
profits.I think that it is worth considering what consequences this
same policy has wrought in the market for flu vaccines - the government
buys most of the nation's vaccines, and many flu vaccine producers have
since proceeded to get out of the flu vaccine business, which left (pardon
the pun) all of our eggs in one basket.   

Its worth noting that the UK and their nationalized health care system is
in the same boat that we are.

JDG 


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RE: One Flu over the Cookoo's Nest

2004-10-21 Thread Horn, John
 Behalf Of JDG
 
 Lately many liberals have suggested that the US government 
 should use its
 buying power to try and drive down prescription drug prices and
lower
 profits.I think that it is worth considering what 
 consequences this
 same policy has wrought in the market for flu vaccines - the 
 government
 buys most of the nation's vaccines, and many flu vaccine 
 producers have
 since proceeded to get out of the flu vaccine business, which 
 left (pardon
 the pun) all of our eggs in one basket.   

I don't know.  In another thread, there is a discussion of whether
NASA is in trouble because they are relying on a limited number of
suppliers.  That certainly isn't because of cost reduction issues at
NASA, I don't believe.  I think this has more to do with the second
part of your email: the government buys most of the vaccine.
Wouldn't that make for limited suppliers as there isn't much
competition for buyers, regardless of price?  

 - jmh
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Re: One Flu over the Cookoo's Nest

2004-10-21 Thread William T Goodall
On 21 Oct 2004, at 1:39 pm, JDG wrote:
At 10:57 PM 10/20/2004 -0700 Doug Pensinger wrote:
Think the shortage of flu vaccine is just bad luck?
Lately many liberals have suggested that the US government should use 
its
buying power to try and drive down prescription drug prices and lower
profits.I think that it is worth considering what consequences this
same policy has wrought in the market for flu vaccines - the government
buys most of the nation's vaccines, and many flu vaccine producers have
since proceeded to get out of the flu vaccine business, which left 
(pardon
the pun) all of our eggs in one basket.

Its worth noting that the UK and their nationalized health care system 
is
in the same boat that we are.

According to the linked story the UK Health Service had already 
arranged for an additional 1.2 million doses from some of its five 
other suppliers by the end of the month, with an additional 1 million 
due to arrive by mid-November. 

What boat are you talking about?
--
William T Goodall
Mail : [EMAIL PROTECTED]
Web  : http://www.wtgab.demon.co.uk
Blog : http://radio.weblogs.com/0111221/
There is no reason anyone would want a computer in their home.   -- 
Ken Olson, President, Chairman and Founder of Digital Equipment Corp., 
1977

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RE: One Flu over the Cookoo's Nest

2004-10-21 Thread John D. Giorgis
At 08:24 AM 10/21/2004 -0500 Horn, John wrote:
I don't know.  In another thread, there is a discussion of whether
NASA is in trouble because they are relying on a limited number of
suppliers.  That certainly isn't because of cost reduction issues at
NASA, I don't believe.  I think this has more to do with the second
part of your email: the government buys most of the vaccine.
Wouldn't that make for limited suppliers as there isn't much
competition for buyers, regardless of price?  

Not necessarily.   There is no reason for the government to buy all of its
supply from one place, as it does not appear that flu vaccine production
has irresistable economies of scale.

I think this blog does a good analysis of what is going on here:
  http://cafehayek.typepad.com/hayek/2004/10/the_cause_of_th.html

JDG
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RE: The Flu!

2003-12-12 Thread Deborah Harrell
--- Gary Nunn [EMAIL PROTECTED] wrote:
 John wrote

  In all of the news reports, they keep talking
 about the 
  number of people who have died from the flu so far
 and how 
  they are all children.  As a parent of small
 children of my own, does any one
  know what age those kids are?   How concerned
 should we be about this?

 My Kids are 9 and 2.5, and I had both of them
 vaccinated last week. My 9
 year old daughter has mild asthma and is considered
 high risk. My 2 year
 old is supposed to get a second shot in 30 days, but
 I suspect that they
 will be out of vaccination by then.
 
 I looked over the news reports and the CDC website,
 and although they
 are somewhat vague, it appears that it is primarily
 the high risk
 children that have the highest mortality rate. By
 high risk I mean kids
 with severe asthma, suppressed immunity, less than
 24 months old, etc.
 Although, there have been reports of perfectly
 healthy 10 year olds kids
 that didn't survive, but I really think that
 occurrence is very rare.

Colorado has had 9 documented flu-related child
deaths, and 1 or 2 more are still being investigated;
ages ranged from 22 months to ~15yo.  Almost half of
these children had no known underlying illnesses,
while the others had various chronic conditions such
as asthma, diabetes and cancer.  One complication that
seems to be more of a problem this year is secondary
infection (pneumonia, mostly) with
*community-acquired* methicillin-resistant
_Staphalococcus aureus_[MRSA]; this used to be
primarily a hospital-acquired infection, so those
without hospital exposure weren't at risk.  MRSA
infections have to be treated with different
antibiotics than most primary care docs would
ordinarily use for bronchitis or pneumonia -- they're
more expensive, and some have to be given IV rather
than orally.  Here is one article with links:
http://www.9news.com/storyfull.aspx?storyid=21811
(Because of CO's high rate of flu  related deaths,
most of the local stations have put up doctor-assisted
sites/info for the community.)

Children, especially the very young, frequently have
atypical symptoms as well: rather than a high fever
with severe chills and body aches, they might have
hoarse breathing, tummy ache with diarrhea, or a bad
headache.  They also seem to get dehydrated more
easily (in a baby or toddler, a parent would notice
decreased need for diaper changes).  Since children
have smaller airways than adults, and a smaller body
volume, they do not tolerate clogged airways or
dehydration as well (well, it's a little more complex
than that, with children's immature immune systems a
big factor, but you get the picture).

For a healthy child over 5yo, an alternative to the
shot is the nasally-administered vaccine (it's called
FluMist); this is an attenuated live virus rather than
a killed virus as in the shot, so cannot be given to a
child with a compromised immune system.  It is also
more expensive than the regular shot.  Of course, this
year, there is a slight mismatch between the viral
strains used to prepare the vaccine and one of the
actual variety that's going around: the Fujian
variant.  Still, most experts think that getting the
vaccine will result in a less-severe infection even
with the mismatch.

This is the CDC site, with multiple links and FAQs,
including info on the nasal vaccine and maps outlining
cases across the country (I think most states have set
up websites on the flu, but you can see what's been
reported to the CDC here):
http://www.cdc.gov/flu/

To add to the confusion, there is apparently at least
one other respiratory virus going around that can be
confused with the flu; there are laboratory tests that
can identify flu infection in less than an hour (with
reasonable accuracy for such rapidity, but there can
be up to 30% false-negative rate).  Here is the CDC
site on diagnosis:
http://www.cdc.gov/flu/professionals/labdiagnosis.htm

For reference, the flu and its complications kill from
20,000 to 36,000 people in the US every year;
periodically a pandemic will sweep the world killing
millions. (Frex the 1917-8 pandemic, which might have
been a fusion virus rather than the pure human
influenza virus; I've seen research leaning towards an
avian or swine flu pass-through.  When humans and
animals live in close proximity under poor sanitation
 hygeine, some viruses 'jump' from one species to
another: if an individual, human or animal, has an
active infection with more than one influenza virus,
there can be some mixing of genes, and the resultant
virus might be even more virulent or communicable than
the standard varieties.  Of course, most such fusions
probably are _less_ hardy, and unable to pass through
one species into another, which is one of the reasons
we don't have more pandemics.  This is why the WHO and
CDC pounced so hard on the SARS infection; many
epidimiologists think we are past due for a bad
pandemic.)  

I couldn't find any hard data on national child
mortality from influenza 

RE: The Flu!

2003-12-12 Thread Ronn!Blankenship
From CNN QuickNews today:

The number of states severely hit by the flu has more than doubled since last
week and the illness is hitting the western part of the nation particularly
hard, federal health officials reported Thursday. CNN's Dr. Sanjay Gupta
shares tips to keep you from catching the flu. Wipe down your keyboard and
your phone, he suggests. Ninety-nine percent of germs will be taken care of
by this. Just to put it in perspective, your keyboard and your phone have 400
times the number of germs as a toilet seat.
Dr. Sanjay Gupta is a medical correspondent for CNN and appears on CNN's
American Morning with the latest medical news, health tips, and more to help
viewers understand the world of medicine and how it relates to them.


-- Ronn!  :)

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RE: The Flu!

2003-12-11 Thread Gary Nunn

John wrote
 In all of the news reports, they keep talking about the 
 number of people who have died from the flu so far and how 
 they are all children.  As a parent of small children of my 
 own, does any one
 know what age those kids are?   How concerned should we be about
 this?


My Kids are 9 and 2.5, and I had both of them vaccinated last week. My 9
year old daughter has mild asthma and is considered high risk. My 2 year
old is supposed to get a second shot in 30 days, but I suspect that they
will be out of vaccination by then.

I looked over the news reports and the CDC website, and although they
are somewhat vague, it appears that it is primarily the high risk
children that have the highest mortality rate. By high risk I mean kids
with severe asthma, suppressed immunity, less than 24 months old, etc.
Although, there have been reports of perfectly healthy 10 year olds kids
that didn't survive, but I really think that occurrence is very rare.

There are a couple of schools that have been closed here in Ohio due to
the flu, and I expect the 2 week Christmas break will slow down the rate
of infection somewhat since kids won't be clustered together in
classrooms.


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Re: The Flu!

2003-12-11 Thread John D. Giorgis
At 07:31 PM 12/11/2003 -0600 Horn, John wrote:
In all of the news reports, they keep talking about the number of
people who have died from the flu so far and how they are all
children.  As a parent of small children of my own, does any one
know what age those kids are?   How concerned should we be about
this?

A 20-year-old college-age student was the first flu death of the year in
Massachusetts today.

JDG - Who has been trying to get his shot for a month now, but hasn't
managed to stay healthy for two straight days in order to do it. :-(

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