The gtk+-3.22.28 package is not reproducible because of a single file:
share/icons/hicolor/icon-theme.cache
The contents of this file appear not be sorted deterministically:
--8<---cut here---start->8---
diffoscope
/gnu/store/1qqyd1mhydh19qcis13kg3455lfm9vv5-gtk+-3.22.28/share/icons/hicolor/icon-theme.cache
/tmp/gtk/share/icons/hicolor/icon-theme.cache
---
/gnu/store/1qqyd1mhydh19qcis13kg3455lfm9vv5-gtk+-3.22.28/share/icons/hicolor/icon-theme.cache
+++ /tmp/gtk/share/icons/hicolor/icon-theme.cache
│? 'showttf' not available in path. Falling back to binary comparison.
@@ -21,13 +21,13 @@
0140: 0150 016c ...P...l
0150: 6774 6b33 2d64 656d 6f2d 7379 6d62 6f6c gtk3-demo-symbol
0160: 6963 2e73 796d 626f 6c69 6300 0006 ic.symbolic.
0170: 0005 0004 0004 0004
0180: 0003 0004 0002 0004
0190: 0001 0004 0004
01a0: 0006 01bc 01c8 01d4
-01b0: 01e0 01ec 01fc 3232 7832 22x2
+01b0: 01e0 01ec 01f8 3332 7833 32x3
01c0: 322f 6170 7073 3136 7831 362f 6170 2/apps..16x16/ap
-01d0: 7073 3438 7834 382f 6170 7073 ps..48x48/apps..
-01e0: 3234 7832 342f 6170 7073 3235 3678 24x24/apps..256x
-01f0: 3235 362f 6170 7073 3332 7833 256/apps32x3
-0200: 322f 6170 7073 2/apps..
+01d0: 7073 3234 7832 342f 6170 7073 ps..24x24/apps..
+01e0: 3438 7834 382f 6170 7073 3232 7832 48x48/apps..22x2
+01f0: 322f 6170 7073 3235 3678 3235 362f 2/apps..256x256/
+0200: 6170 7073 apps
--8<---cut here---end--->8---
--
Ricardo
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