[ccp4bb] job offer: Software Architects / Engineers - MPI Dortmund

[Stefan Raunser]

Dear colleagues,
I would like to draw your attention to the following job opportunity.

Best
Stefan


The Max Planck Institute of Molecular 
Physiology (MPI) is in search 
of two experienced Software Architects / Engineers  to join the development 
team of SPHIRE, which is a software for the semi-automated processing of single 
particle electron cryo-microscopy (cryo-EM) data. Further information on SPHIRE 
is available at: http://sphire.mpg.de.

Joining this team will provide you with the benefit of working closely in a 
dynamic and international environment involving scientists from a variety of 
academic fields. You will be expected to work on existing SPHIRE modules, as 
well as introducing new innovations to the framework. In particular, you will 
have the opportunity to contribute to the research and development of topics 
including: machine/deep learning, image processing, parallel processing and 
data visualization. Our code is primarily written in Python but individual 
modules may also require C++ or CUDA integration.

Qualifications and Experience

You hold a postgraduate degree in computer science or in an equivalent 
discipline with at least four years of experience as a professional software 
developer. You apply best practices of modern software development such as unit 
testing, source control (git), and build management. You communicate fluently 
in English, both written and verbal. You routinely produce clean and 
maintainable code and appreciate the value of clear documentation. Previous 
experience in scientific software development and handling of biological data 
would be an advantage.

Your responsibilities

Your primary responsibilities include:

  *   Revising and modernizing the internal software architecture of SPHIRE
  *   Identifying and implementing new cutting-edge algorithms
  *   Designing new SPHIRE modules
  *   Maintaining existing SPHIRE modules

Working at the MPI

The internationally renowned MPI of Molecular Physiology in Dortmund is 
well-equipped and will provide you with all the high-end gadgets you need for 
your work as a developer. The SPHIRE framework is currently used to produce 
results on the cutting edge of structural biochemistry. You will be surrounded 
by highly motivated developers and scientists from all over the world, 
employing a wide range of both technical and scientific expertise.

Payment

We offer full-time employment in a modern, international work environment. The 
position is to be filled immediately and is initially limited for three years. 
Remuneration is paid in accordance with the collective agreement of the public 
service (TVöD Bund), taking account your qualifications and professional 
experience. In addition, social benefits correspond to those of public service.

Application

The Max Planck Society is committed to increasing the number of individuals 
with disabilities in its workforce and therefore encourages applications from 
such qualified individuals.
The Max Planck Society seeks to increase the number of women in those areas 
where they are underrepresented and therefore explicitly encourages women to 
apply.

Please send your CV, two references, and a statement outlining your relevant 
work experience until September 30 to Stefan Raunser at 
raunser-jobsea...@mpi-dortmund.mpg.de

Prof. Dr. Stefan Raunser, Max Planck Institute of Molecular Physiology, 
Department of Structural Biochemistry, Otto-Hahn-Str. 11, 44227 Dortmund

-
Stefan Raunser

Director, Department of Structural Biochemistry
Max Planck Institute of Molecular Physiology
Otto-Hahn-Str. 11
44227 Dortmund, Germany
tel: +49-231-133-2300




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[ccp4bb] Postdoctoral positions in Drug Discovery at Newcastle University

[Martin Noble]

Dear all,

May I draw your attention to recruitment that we have in process for structural 
biologists to join our drug-discovery team here at the Northern Institute for 
Cancer Research ?

There is a deadline of 12th September for a post currently advertised at

https://www.jobs.ac.uk/job/BMG197/research-assistant-associate-structural-biology-a146128r

Structural biologists at NICR form part of an extremely enjoyable and 
pleasingly effective drug discovery program that brings together talents from 
chemistry, cancer bioscience and structure/biophysics to discover next 
generation small molecular therapies for cancer.  The structure and biophysics 
team comprises about 8 people who each work on one or more projects. Our 
responsibilities are is to make proteins, build assays, and solve structures, 
and to play a full role in the design process for iterative medicinal chemistry.

Each target has a team drawn from each of the disciplines, and teamwork is an 
essential part of what we are about.  When we are blowing Newcastle’s trumpet, 
we highlight that the group here has played important roles in delivering two 
drugs to the clinic that have been approved for cancer therapy in the last two 
years.  We are optimistic that this winning streak will continue, and are 
looking for staff who share our enthusiasm for making cutting edge structural 
and biophysical work really count.

Applicaitons should be made through the university website, but Prof. Jane 
Endicott (jane.endic...@ncl.ac.uk) or I can be 
approached informally to learn more.

With thanks and best wishes,

Martin




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[ccp4bb] ADTB-2018

[ferrer]

Workshop on**



*Advanced Diffraction Techniques for Biology*

5-9November 2018

EPN campus, Grenoble, France





It is our pleasure to announce the first workshop on Advanced 
Diffraction Techniques for Biology in the EPN campus at Grenoble, France.


The course will cover X-rays, neutrons and electrons diffraction by 
crystals of biological macromolecules. Various techniques will be 
investigated:


 *

   Macromolecular crystal growth

 *

   /In situ/ (in plate) X-ray diffraction

 *

   Serial X-ray crystallography

 *

   Time resolved X-ray crystallography

 *

   Neutron diffraction

 *

   Electron diffraction of nano-crystals

with the aim of solving /de novo/ structures, searching ligands, 
elucidating reaction mechanisms...


This 1-week course will combine theoretical lectures and practicals on 
ESRF beamlines and other EPN instruments. It is dedicated 
toresearchers(advanced PhD, PostDoc, Scientist) interested in 
macromolecular structural studies at atomic resolution using 
crystallographicapproaches.


The course will take place from November5 toNovember9,2018 at the EPN 
campus, Grenoble, France. To apply, please, send a short CV (1 page 
max.) and a motivation letter to marta.elzo-aiza...@ibs.fr**before 
September 15, 2018.


The registration is free and includes accommodationand meals on the EPN 
campus.Selectedapplicants will be notified by e-mail on September 30, 
2018. Participants will have to pay for their travel expenses. More 
details about the workshop can be found on the dedicated web 
site:http://workshops.ibs.fr/adtb-2018 




The ADTB Comity


(ADTB is funded by IBS, EMBL, ESRF, CBS, FRISBI, CRISTECH, AFC, UGA, 
Grenoble INP, CNRS, and CEA)






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Re: [ccp4bb] Post Doc position available in Denmark

[Bjørn Panyella Pedersen]

Just a brief reminder of the following open position. Deadline is in ten days. 

All the best,
-Bjørn


From: CCP4 bulletin board  on behalf of Bjørn Panyella 
Pedersen 
Sent: Monday, August 13, 2018 13:31
To: CCP4BB@JISCMAIL.AC.UK
Subject: [ccp4bb] Post Doc position available in Denmark

Postdoctoral position in Structure of Sterol Transporting Membrane
Proteins at Aarhus University, Denmark.

online posting:
http://www.pedersenlab.dk/source/bp_lab_postdoc_position.pdf


The Pedersen group is looking for a highly skilled and motivated postdoc
with an interest in working on sterol and hormone transporting membrane
transporters and with a proven track record in the area of structural
and/or functional analysis of membrane proteins.

The position will be open from fall 2018, and starting date is
negotiable. Funding is available for at least 2 years of employment,
with an automatic extension possible for up to a total maximum of 4 years.

The position:
The position seeks to strengthen ongoing activities in the laboratory of
Bjørn P. Pedersen on structure, related to the function and mechanism of
sterol-transporting membrane proteins (pedersenlab.dk). The laboratory's
interest is the interplay between structure and function of
transmembrane transport processes with a focus on metabolite uptake
systems, and the methods uses are primarily crystallography, cryo-EM and
biochemistry. The group is part of the Section of Structural Biology at
Aarhus University.

The candidate:
A successful candidate has a relevant Ph.D. degree and a solid and
documented background in structural biology, biochemistry and/or
biophysics. Experience with membrane protein expression and purification
is favored, and the candidate must demonstrate an ability and interest
to work with membrane proteins with a structural aim. Finally,
applicants should be ambitious, show strong collaborative skills, and
should also be able to take initiatives and responsibility within the
work environment.

Deadline:
All applications must be made online and received by 16/09/2018.




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