[ccp4bb] NCCAT 2020-C2 CryoEM access proposal deadline - January 1, 2020 - NYC, USA

[Ed Eng]

​Dear all,

NCCAT's next application deadline for cryoEM access is January 1, 2020. Given 
the holiday season, there will be a one (1)-time deadline extension. New 
applications submitted to our Proposal Central by 5pm EST on January 3, 2020 
will be considered within 2020’s scheduling cycle2 (2020-C2).

Apply now: http://nccat.nysbc.org/proposalcentral/ .

We have two (2) access categories:
1) General User Proposal (GUP) that supports instrumentation access, and
2) cross-Training Program (TP) that assists users in the development of cryoEM 
skills needed for independent research.

This cycle, we are prioritizing the GUP1 early access program, which supports 
single-particle cryoEM data collection on one of our existing three (3) Krios 
instruments, and our cross-training programs.

NCCAT is committed to an open and transparent application process to ensure 
equal-opportunity nationwide access. For more information visit nccat.nysbc.org 
.

Best,
Ed Eng (NCCAT)

The Transformative High Resolution Cryo-Electron Microscopy Program
National Cryo-EM Service Centers - 
commonfund.nih.gov/CryoEM
 Stanford-SLAC Cryo-EM Center (S2C2) - 
cryoem.slac.stanford.edu/s2c2
 Pacific Northwest Center for Cryo-EM (PNCC) - pncc.online
 National Center for CryoEM Access and Training (NCCAT) - 
nccat.nysbc.org


---
Edward T. Eng, Ph.D.
NCCAT: National Center for CryoEM Access and Training
SEMC: Simons Electron Microscopy Center
NYSBC: New York Structural Biology Center
89 Convent Ave, NY, NY 10027
nccat.nysbc.org semc.nysbc.org
(212)939-0660 x346



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[ccp4bb] post-doctoral position

[David Mueller]

A NIH (5 year budget) funded position for post-doctoral fellow is open in
the Chicago Medical School, Rosalind Franklin University, in the lab of
David Mueller,  for the study of the structure and function of the yeast
ATP synthase and that of the protein defective in the juvenile form of
Batten disease, Cln3.  We use a combination of x-ray crystallography and
cryo-EM, with molecular biology, protein expression and purification, and
yeast genetics.  Experience in biochemistry, including protein expression
and purification is essential.   See this site to apply and for application
details.

https://workforcenow.adp.com/mascsr/default/mdf/recruitment/recruitment.html?cid=395a4546-652f-4dd9-832f-b02e894ced6e=19000101_01=300079=CC3=en_US


-- 
David M. Mueller
Center for Genetic Diseases
The Chicago Medical School
Rosalind Franklin University of Medicine and Science
 Green Bay Road
North Chicago, IL 60064


*david.muel...@rosalindfranklin.edu
http://lmb-il.org/index.html
 *Office: 847-578-8606
FAX: 847-578-3240



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[ccp4bb] Dead link

[David J. Schuller]

On this CCP4 documentation page:

http://www.ccp4.ac.uk/html/phaser.html

The link for "Full documentation" goes nowhere.


-- 
===
All Things Serve the Beam
===
David J. Schuller
modern man in a post-modern world
MacCHESS, Cornell University
schul...@cornell.edu




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[ccp4bb] Faculty position at OSU

[Marcos Sotomayor]

Dear all,

The Department of Chemistry and Biochemistry at The Ohio State University has 
an opening for a faculty position in Biochemistry (broadly defined); areas of 
interest include Cryo-EM, systems biology, single molecule methods, synthetic 
biology, among others.

I would be grateful if you could bring the position to the attention of 
qualified applicants.

Thank you!
Marcos Sotomayor

Application instructions here: https://academicjobsonline.org/ajo/jobs/15710 


Description:
Department: Chemistry and Biochemistry
Position: Biochemistry
Rank: Assistant Professor   
Description:  The Department of Chemistry & Biochemistry in the College of Arts 
and Sciences at The Ohio State University seeks to fill a tenure-track faculty 
position at the assistant professor level in the general area of biochemistry, 
broadly defined.  The new faculty member will join an interdisciplinary 
community on the main campus in Columbus, Ohio. Our partners and outstanding 
facilities, including state-of-the-art cryo-electron microscopy, NMR 
spectroscopy, mass spectrometry and systems biology, offer numerous 
opportunities for collaboration and advancement of research programs.

Qualifications:  A Ph.D. in Chemistry, Biochemistry or a related field is 
required at the time of appointment. The position will begin in Autumn 2020. 
Demonstrated potential excellence in innovative research addressing fundamental 
questions of biological/biomedical significance and a strong commitment to 
teaching are essential. Outstanding applicants in all areas of molecular 
biochemistry and biophysics will be considered but priority will be given to 
those candidates whose research interests complement those of existing faculty. 
As a campus with a continuously growing diverse student body, we encourage 
applications from women and other underrepresented minority groups. Appointment 
is contingent on the university’s verification of credentials and other 
information required by law and/or university policies, including but not 
limited to a criminal background check.
About Columbus:  The Ohio State University campus is located in Columbus, the 
capital city of Ohio. Columbus is the Midwest’s fastest-growing city and the 
nation’s 14th largest city. Columbus offers a diverse array of welcoming 
neighborhoods and a vibrant arts and culture scene. Additional information 
about all that the Columbus area has to offer is available at 
https://visit.osu.edu/experience .
Application Instructions:  Apply to Academic Jobs Online. A complete 
application consists of a cover letter, curriculum vitae, research, teaching, 
and diversity statements.  The diversity statement should articulate your 
demonstrated commitments and capacities to contribute to diversity, equity, and 
inclusion through research, teaching, mentoring, and/or outreach and 
engagement. Three letters of reference will be required. Review of applications 
will begin on December 20, 2019 and will continue until the position is filled. 
Inquiries may be directed to Prof. Mark Foster, Search Committee Chair at 
foster@osu.edu .
The Ohio State University is committed to establishing a culturally and 
intellectually diverse environment, encouraging all members of our learning 
community to reach their full potential. We are responsive to dual-career 
families and strongly promote work-life balance to support our community 
members through a suite of institutionalized policies. The university is an 
ADVANCE  Institution and member of the Ohio/Western 
Pennsylvania/West Virginia Higher Education Recruitment Consortium (HERC).

The Ohio State University is an equal opportunity employer. All qualified 
applicants will receive consideration for employment without regard to race, 
color, religion, sex, sexual orientation or identity, national origin, 
disability status, or protected veteran status.


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[ccp4bb] PhD opportunities at the Leicester Institute of Structural and Chemical Biology, University of Leiceste

[Louise Fairall]

Please can I draw your attention that there are many studentships available at 
The Leicester Institute of Structural and Chemical Biology, University of 
Leicester. For an overview see: https://le.ac.uk/liscb/study-at-liscb 

 

There are three opportunities available in my own research group investigating 
the structure and function of 7 large Histone Deacetylase complexes that 
control the epigenetic regulation of gene expression.

 

Option 1:

3.5-year studentship funded by the MRC IMPACT DTP 

 (Deadline 12 January)

Unravelling the enigma of why humans require seven distinct histone deacetylase 
complexes – implications for therapeutic intervention

 

Option 2:

4-year studentship funded by the BBSRC MIBTP 

 (Deadline 17 January)

Cryo-Electron Microscopy of Histone Deacetylase Complexes

 

Option 3:

3-year studentship 

 funded by the College and LISCB (Deadline 6 January)

Understanding epigenetic complexes that regulate gene expression.

 

If you have any questions please do not hesitate to get in touch: 
john.schw...@le.ac.uk

Note that the deadlines fall in early January.

 

Best wishes to you all for the coming holidays…

 

John Schwabe


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[ccp4bb] Funded technician position in Marseille

[Elsa Garcin]

Please see description below.

Technician in Biochemistry.
Context. A funded full-time Ingenieur d’Etudes position (A*MIDEX) is available 
in the new team of Elsa Garcin (Professor at AMU starting in January 2020, 
Chaire d’Excellence A*MIDEX; Adjunct Associate Professor at UMBC: 
https://sites.google.com/a/umbc.edu/garcinlab/) in the Laboratoire 
d’Information Génomique et Structurale (IGS), a CNRS/AMU laboratory located on 
the Luminy Campus of Aix-Marseille University. The IGS is a dynamic lab led by 
Chantal Abergel and a world-renowned expert in giant virus research 
(https://www.igs.cnrs-mrs.fr/les-publications/). Giant virus discovery was 
revolutionary for the field of virology, as they revived old debates about the 
concept of virus, their position in the tree of life, their biology, and the 
role they may have played in the emergence of life on earth. Characterizing new 
metabolic pathways in these viruses may therefore provide new clues about 
chemical and biological processes at the origin of life. The primary goal of 
the candidate will be to participate in the A*MIDEX Chaire d’Excellence Project 
“Structural Biochemistry of Novel Metabolic Pathways in Giant Viruses” led by 
Elsa Garcin.

Tasks. The principal activity of the successful candidate will be to conceive 
and perform experiments under the guidance and supervision of the project 
leader and in close collaboration with other team members. Learning new 
techniques specific to this project will be required. All results will be 
reported in lab notebooks, discussed with the project leader, and presented at 
lab meetings. English or French required.

Experience and skills. We are looking for an enthusiastic, organized, and 
motivated candidate. The successful candidate will have expertise in molecular 
biology, bacterial and/or eukaryotic protein expression, and protein 
purification. Mastering of basic lab techniques in molecular biology (PCR, 
cloning, site-directed mutagenesis) and biochemistry (protein production, 
purification, SDS-PAGE, Western blot) is required. Cell biology experience is a 
plus, but not required. 

Constraints, risks. The successful candidate will work on projects depending 
heavily on cell biology and structural biology. The candidate will produce and 
purify proteins and complexes for structural studies by crystallography, 
small-angle x-ray scattering, electron microscopy, and NMR.  Accordingly, the 
candidate will perform experiments with the non-pathogenic bacteria Escherichia 
coli. In addition, the candidate will perform experiments with the giant virus 
host, Acanthamoeba castellanii, and associated virus (Mimivirus, Megavirus, …). 
Work with these organisms will require strict adherence to safety protocols 
already in place at the IGS.

How to apply: Interested applicants should send their application by email to 
Elsa Garcin (gar...@igs.cnrs-mrs.fr), including a cover letter describing their 
motivation for joining the team, and curriculum vitae. They should also arrange 
for two letters of recommendation to be sent directly by email to Elsa Garcin 
(gar...@igs.cnrs-mrs.fr). Review of application materials will begin January 
1st 2020. 
Aix-Marseille University is an affirmative action, equal opportunity employer. 
Women and minority candidates are encouraged to apply.

Contract:
Start date: March 1st, 2020
Contract type: CDD Technique/Administratif
Duration: 12 months (renewable depending on results for a maximum of 33 months 
total)
Salary: salary will be calculated based on the successful candidate’s experience
Location: IGS, UMR7256 AMU/CNRS, Parc scientifique de Luminy, 163 avenue de 
Luminy, 13288 Marseille, France
Minimum level required: Bac+5 (Master 2 level)



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[ccp4bb] Funded Postdoctoral position in Marseille

[Elsa Garcin]

Dear colleagues, 
We are looking for candidates. 
Please see the description of the position below and disseminate widely.

Postdoctoral position in Structural Biology of Giant Viruses
Context. A funded postdoctoral position (A*MIDEX) is available in the new team 
of Elsa Garcin (Professor at AMU starting in January 2020, Chaire d’Excellence 
A*MIDEX; Adjunct Associate Professor at UMBC: 
https://sites.google.com/a/umbc.edu/garcinlab/) in the Laboratoire 
d’Information Génomique et Structurale (IGS), a CNRS/AMU laboratory located on 
the Luminy Campus of Aix-Marseille University. The IGS is a dynamic lab led by 
Chantal Abergel and a world-renowned expert in giant virus research 
(https://www.igs.cnrs-mrs.fr/les-publications/). Giant virus discovery was 
revolutionary for the field of virology, as they revived old debates about the 
concept of virus, their position in the tree of life, their biology, and the 
role they may have played in the emergence of life on earth. Characterizing new 
metabolic pathways in these viruses may therefore provide new clues about 
chemical and biological processes at the origin of life.

Goals. The postdoctoral project aims at deciphering novel metabolic pathways in 
giant viruses, and is focused on structure-function studies of giant virus 
proteins. The successful candidate will join an interdisciplinary team of 
bioinformaticians, cell biologists, virologists, protein chemists, and 
structural biologists. The project will be carried out in close collaboration 
with partner labs (IBS Grenoble, spectroscopy; BIP, EPR) and groups and 
platforms at the Institut de Microbiologie de la Mediterannée (EPR, Proteomics, 
Microscopy, Biophysics). 

Required education, experience, and skills. We are looking for a highly 
motivated, scientifically independent and creative fellow, who can contribute 
to a team environment. To be eligible for this postdoctoral position, 
candidates must have completed their PhD within the last two to five years at 
the start of the contract. A PhD in Biochemistry, Biophysics or a closely 
related discipline is required. Candidates should have a strong background in 
biochemistry, molecular and cellular biology, protein expression and 
purification. Prior research experience in at least one of the following areas 
is mandatory: protein or RNA biochemistry, x-ray crystallography, and electron 
microscopy. Experience with anaerobic techniques is a plus, but not required. 
Candidates should have strong communication skills, the ability to conduct 
research independently, to prepare manuscripts and presentations, and the 
ability and willingness to work with graduate and undergraduate students in the 
laboratory. Working language is English; knowledge of French is not required.

How to apply: Interested applicants should send their application by email to 
Elsa Garcin (gar...@igs.cnrs-mrs.fr), including a cover letter describing their 
current and future research interests and motivation for joining the team, and 
curriculum vitae with complete publication list. They should also arrange for 
three letters of recommendation to be sent directly by email to Elsa Garcin 
(gar...@igs.cnrs-mrs.fr). Review of application materials will begin January 
1st 2020.
Aix-Marseille University is an affirmative action, equal opportunity employer. 
Women and minority candidates are encouraged to apply.

Contract.
Start date: March 1st, 2020
Duration: 12 months (renewable depending on results for a maximum of 33 months 
total)
Salary: salary will be calculated based on the successful candidate’s experience
Location: IGS, UMR7256 AMU/CNRS, Parc scientifique de Luminy, 163 avenue de 
Luminy, 13288 Marseille, France

Contact information: Elsa D Garcin (gar...@igs.cnrs-mrs.fr)



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