[ccp4bb] Postdoctoral Research Associate –Invasive fungal and bacterial diseases – (Brookhaven National Laboratory, Upton, New York)

2023-12-27 Thread Qun Liu
Dear All:

Brookhaven National Laboratory has Postdoc openings to research molecular
and structural determinants involved in invasive fungal and bacterial
diseases. The positions will also
study the mechanisms of drug resistance and develop improved or novel
drugs. If you are interested, please see the job description details
through the link provided below.

https://jobs.bnl.gov/job/upton/postdoctoral-research-associate-invasive-fungal-and-bacterial-diseases/3437/59219260336

Warm regards,
Qun Liu
Biology Department & NSLS-II
Brookhaven National Laboratory



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Re: [ccp4bb] nearestcell

2023-12-27 Thread Kay Diederichs
Dear all,

a short summary:

- SAUC and the Phenix tool worked well.
- SIMBAD was also pointed out to me, but it stops with an error message both in 
my local CCP4 installation and in "CCP4 online".
- The https://app.strubi.ox.ac.uk/nearest-cell/nearest-cell.cgi alternative to 
http://www.strubi.ox.ac.uk/nearest-cell/nearest-cell.cgi does not respond
- "othercell" is also useful but for other purposes, and it is in CCP4

thanks to all who responded so quickly!

Kay

On Wed, 27 Dec 2023 18:38:15 +, Kay Diederichs 
 wrote:

>Dear all,
>
>I seem to remember a tool called "nearestcell", a command-line equivalent of 
>the Oxford Nearest-Cell web server which appears to be offline.
>However I cannot locate that tool in CCP4 nor elsewhere. Can anyone point me 
>to it or give alternatives, please? (I did try the PDB's advanced search but 
>it is not made for this purpose)
>
>Thanks, and a happy and successful 2024 to everybody!
>
>Kay
>
>
>
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Re: [ccp4bb] nearestcell

2023-12-27 Thread Herbert J. Bernstein
That is a live link to sauc, but I have not updated the database from the
PDB in a while.  Let me know if there is an
urgent need for an update,  Otherwise I am planning one for March.  I
normally build the database from COD and
the PDB, but if CCDC wishes, we can add the CSD to the mix.   For the
longer term, would anybody be
willing to provide an institutional home?

Regards,
Herbert

On Wed, Dec 27, 2023 at 1:47 PM Mike S  wrote:

> Hi Kay,
>
> http://flops.arcib.org:8084/sauc-1.1.1/
>
> similar to the nearest-cell server, which seems to change its link and is
> harder to find (or stale link)
> https://app.strubi.ox.ac.uk/nearest-cell/nearest-cell.cgi
>
> HTH,
> Mike
>
> On Wed, Dec 27, 2023 at 1:39 PM Kay Diederichs <
> kay.diederi...@uni-konstanz.de> wrote:
>
>> Dear all,
>>
>> I seem to remember a tool called "nearestcell", a command-line equivalent
>> of the Oxford Nearest-Cell web server which appears to be offline.
>> However I cannot locate that tool in CCP4 nor elsewhere. Can anyone point
>> me to it or give alternatives, please? (I did try the PDB's advanced search
>> but it is not made for this purpose)
>>
>> Thanks, and a happy and successful 2024 to everybody!
>>
>> Kay
>>
>> 
>>
>> To unsubscribe from the CCP4BB list, click the following link:
>> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1
>>
>> This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a
>> mailing list hosted by www.jiscmail.ac.uk, terms & conditions are
>> available at https://www.jiscmail.ac.uk/policyandsecurity/
>>
>
> --
>
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Re: [ccp4bb] nearestcell

2023-12-27 Thread Mike S
Hi Kay,

http://flops.arcib.org:8084/sauc-1.1.1/

similar to the nearest-cell server, which seems to change its link and is
harder to find (or stale link)
https://app.strubi.ox.ac.uk/nearest-cell/nearest-cell.cgi

HTH,
Mike

On Wed, Dec 27, 2023 at 1:39 PM Kay Diederichs <
kay.diederi...@uni-konstanz.de> wrote:

> Dear all,
>
> I seem to remember a tool called "nearestcell", a command-line equivalent
> of the Oxford Nearest-Cell web server which appears to be offline.
> However I cannot locate that tool in CCP4 nor elsewhere. Can anyone point
> me to it or give alternatives, please? (I did try the PDB's advanced search
> but it is not made for this purpose)
>
> Thanks, and a happy and successful 2024 to everybody!
>
> Kay
>
> 
>
> To unsubscribe from the CCP4BB list, click the following link:
> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1
>
> This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a
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> available at https://www.jiscmail.ac.uk/policyandsecurity/
>



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Re: [ccp4bb] nearestcell

2023-12-27 Thread Pavel Afonine
Hi Kay,
to address "(...) not elsewhere (...)", in Phenix GUI go to Tools then down
to "Search PDB symmetry...". I've never used it myself nor do I know who
added it in Phenix but from the description it looks like what you're
looking for. Let us know if you have any problems with it.
All the best,
Pavel


On Wed, Dec 27, 2023 at 10:39 AM Kay Diederichs <
kay.diederi...@uni-konstanz.de> wrote:

> Dear all,
>
> I seem to remember a tool called "nearestcell", a command-line equivalent
> of the Oxford Nearest-Cell web server which appears to be offline.
> However I cannot locate that tool in CCP4 nor elsewhere. Can anyone point
> me to it or give alternatives, please? (I did try the PDB's advanced search
> but it is not made for this purpose)
>
> Thanks, and a happy and successful 2024 to everybody!
>
> Kay
>
> 
>
> To unsubscribe from the CCP4BB list, click the following link:
> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1
>
> This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a
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>



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Re: [ccp4bb] nearestcell

2023-12-27 Thread James Holton

Are you thinking of "othercell" ?

On 12/27/2023 10:38 AM, Kay Diederichs wrote:

Dear all,

I seem to remember a tool called "nearestcell", a command-line equivalent of 
the Oxford Nearest-Cell web server which appears to be offline.
However I cannot locate that tool in CCP4 nor elsewhere. Can anyone point me to 
it or give alternatives, please? (I did try the PDB's advanced search but it is 
not made for this purpose)

Thanks, and a happy and successful 2024 to everybody!

Kay



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[ccp4bb] nearestcell

2023-12-27 Thread Kay Diederichs
Dear all,

I seem to remember a tool called "nearestcell", a command-line equivalent of 
the Oxford Nearest-Cell web server which appears to be offline.
However I cannot locate that tool in CCP4 nor elsewhere. Can anyone point me to 
it or give alternatives, please? (I did try the PDB's advanced search but it is 
not made for this purpose)

Thanks, and a happy and successful 2024 to everybody!

Kay



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[ccp4bb] Postdoctoral Researcher, Membrane Structural and Functional Biology, Caffrey Lab, Trinity College Dublin, Ireland

2023-12-27 Thread Martin Caffrey
*Postdoctoral Research Fellow*



*Membrane Structural and Functional Biology – Caffrey Lab*



*Trinity College Dublin, Ireland*





*Post Summary. *The Membrane Structural and Functional Biology group seeks
to solve the structure of medically important membrane proteins for use in
structure/function studies and for structure-based therapeutics
development. Target proteins are involved in communicable and
non-communicable diseases.



A postdoctoral research position is available in the Group. We are looking
for a highly motivated, creative, and hardworking individual with
experience in membrane protein structural and functional biology to join
our team at Trinity in a lab that offers superb facilities and a supportive
environment. A primary responsibility will be to take a leadership role in
completing and publishing several extant projects in the Group that are at
various stages of fruition.



*Person Specification. *The candidate must have a Ph.D. in biochemistry,
biophysics, molecular biology, or a related field. Demonstrated success in
recombinant membrane protein production, purification, and functional
characterization along with expertise in macromolecular X-ray
crystallography and/or cryo-electron microscopy is required. The candidate
should be a highly motivated and creative individual who enjoys working as
part of a collaborative, multidisciplinary team. Strong leadership,
communication and teaching skills are decided assets. A willingness and
freedom to travel worldwide on short-term projects is expected.



*Salary.* €42,782 - €50,539 per annum depending on experience


*Closing Date.* Until the position is filled

*Principal Investigator. *Martin Caffrey
https://www.tcd.ie/Biochemistry/research/caffrey/

*Application Procedure.* Candidates are asked to submit a letter detailing
education, training, and laboratory experience. In the letter, the
candidate should outline why they feel they are suitable for the position
in an interdisciplinary group that will involve extensive interaction with
collaborators and data collection at facilities around the globe. The
letter of application must be accompanied by a comprehensive CV to include
the names and contact details of two referees (email addresses and phone
numbers to be provided). At least one referee should be an individual the
candidate has worked with and who has agreed to provide a letter of
reference on the candidate’s behalf. The letter and CV should be combined
in a single PDF and emailed to martin.caff...@tcd.ie.

-- 
Martin Caffrey  martin.caff...@tcd.ie
Schools of Medicine and Biochemistry & Immunology
Trinity Biomedical Sciences Institute, Trinity College Dublin
Room 5.62,152-160 Pearse St., Dublin D02 R590, Ireland
website: http://www.tcd.ie/Biochemistry/research/caffrey/
phone: +353-(0)1-896-4253; mobile: +353-(0)86-818-7704



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