[ccp4bb] Permanent position in structural biology at the Micalis institute (Université Paris-Saclay)

[Olivier Berteau]

Dear All,

I would like to draw your attention to the following opportunity.

Best wishes,

Olivier

*--
*

*A permanent research scientist position is due to open soon at the 
Micalis institute (Université Paris-Saclay, INRAE)*


Our research institute MICALIS (UMR1319 INRAE, Université Paris-Saclay) 
in the south Paris, is due to open soon a permanent research scientist 
position in Structural Biology, focusing on the investigation of novel 
enzymes in the context of the human microbiome.


To apply, visit the INRAE Jobs website 
(https://jobs.inrae.fr/en/open-competitions/open-competitions-research-scientists-job-profiles-crcn) 
starting from January 30, 2024.


If you would like to receive a notification in your mailbox, you can 
create job alert here: (https://jobs.inrae.fr/en/campaign-alert-form).


Contact: olivier.bert...@inrae.fr




--


*Dr. Olivier BERTEAU*

/INRAE, Université Paris-Saclay/

/UMR1319 MICALIS, ChemSyBio/

78350 Jouy en Josas cedex, France – phone : +33 (0)1 34 65 23 08

_http://www.micalis.fr_



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Re: [ccp4bb] Manual setting of config file in PyRx

[Magnus Wolf-Watz]

Postdoctoral scholarship (2 years) within Structural Biology of Switchable 
Proteins from Directed Evolution

The Magnus Wolf-Watz laboratory has an opening for a two-year postdoctoral 
scholarship. We are searching enthusiastic candidates that will focus on 
structure determination and mechanistic dissection of proteins with either NMR 
spectroscopy, molecular dynamics simulations or x-ray crystallography. The 
scholarship is full-time for two years with access April 1:st, 2024 or by 
agreement. Last day to apply is February 12 2024.

The scholarship is aimed at a project with a unique combination of directed 
evolution and structural biology focused on development of switchable binders 
towards either; (1) cancer linked receptors and/or (2) purification of 
therapeutic antibodies. The binders are based on small soluble scaffold 
proteins (6-8 kDa) that has been subjected to both negative and positive 
selective pressures in order to render them binding-competent only in the 
presence of a metal ion.  Directed evolution is performed using either 
bacterial display or phage display and the aim of the project is to dissect the 
structural and molecular mechanism that underlies the switchable binding 
capacity. The project is a collaboration with Professor Sophia Hober at the 
Royal Institute of Technology (KTH) in Stockholm.

For inquiries please contact 
magnus.wolf-w...@umu.se

Please submit your application at: 
https://www.umu.se/en/work-with-us/postdoctoral-scholarships/6-37-24/



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[ccp4bb] NOW HIRING: Structural Proteomics position at Human Technopole, Milano

[Sebastiano Pasqualato]

On behalf of Andrea Graziadei:

Dear all,
 
the structural proteomics unit of the National Facility for Structural Biology 
of Human Technopole is looking for a technician!
 
If you’re interested in proteomics, mass spectrometry and structural (systems) 
biology, please consider applying!
 
The Structural Biology National Facility is a newly established, thriving 
department of the Human Technopole (http://www.humantechnopole.it/en/), a fast 
growing new Life Science institute recently established in Milano.
The National Facility, led by Paolo Swuec, provides world-class cryo-EM 
services 
(https://humantechnopole.it/en/facilities/cryo-electron-microscopy-facility/) 
for the research groups at Human Technopole and in the Italian Research 
community. The Facility also comprises platforms for Biophysics,  Biomass 
production, single molecule fluorescence and of course structural proteomics, 
for which help is needed. The unit is equipped with a state of the art Orbitrap 
Eclipse Tribrid mass spectrometer coupled to a Vanquish Neo HPLC and High field 
asymmetric waveform ion mobility spectrometry (FAIMS) and the workflows of the 
facility focus on crosslinking mass spectrometry, with the ambition to expand 
to other structural proteomics workflows.
 
We are looking for a young enthusiastic person with experience in proteomics, 
mass spectrometry and/or structural biology who will assist in instrument 
management and training, and will develop small technological projects of 
interest for the whole Facility, working close with other units, Human 
Technopole scientists and external facility users. 
 
More details on the position, and how to apply, can be found here: 
https://careers.humantechnopole.it/o/techniciansenior-technician-in-structural-proteomics
 . You can contact the manager of the unit, Andrea Graziadei, at 
andrea.grazia...@humantechnopole1.recruitee.com for informal inquiries.
 
thanks and ciao,
Andrea


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