[ccp4bb] Postdoctoral position in X-ray crystallography in Flaherty Lab - Purdue University

[Flaherty, Daniel P]

Hello All,

I wanted to make the community aware of an NIH funded postdoctoral research 
associate position for a structural biologist/X-ray crystallography in my 
group. The position will work to solve the first structures of bacterial 
carbonic anhydrases from pathogenic species of bacteria with and without small 
molecule inhibitors developed in our group.

Please visit https://www.flahertylab.com/positions for more details and 
applications can be submitted at 
https://careers.purdue.edu/job/West-Layayette-Post-Doc-Research-Associate-IN/814628700/

Position is open immediately until filled. Reach out if you have any questions.

Dan

--
Daniel P. Flaherty, PhD
Associate Professor of Medicinal Chemistry
Department of Medicinal Chemistry and Molecular Pharmacology
College of Pharmacy
Purdue University
575 Stadium Mall Dr.
West Lafayette, IN 47907

Email: dfla...@purdue.edu
Phone: 765-494-4761
Lab Website: www.flahertylab.com
Twitter: @FlahertyLab








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[ccp4bb] Research Scientist Position - Flaherty Lab Purdue University

[Flaherty, Daniel P]

Hello All,

My lab in the Department of Medicinal Chemistry and Molecular Pharmacology at 
Purdue University is seeking qualified candidates at the level of Research 
Scientist in the field of Structural Biology for the pursuit of the first 
structures for a high-impact malaria drug target. Please see the position link 
below for details.

https://careers.purdue.edu/job/West-Lafayette-Research-Associate-Life-and-Physical-Sciences-IN-47906/1033137000/

Thanks!
Dan


--
Daniel P. Flaherty, PhD
Associate Professor of Medicinal Chemistry
Department of Medicinal Chemistry and Molecular Pharmacology
College of Pharmacy
Purdue University
575 Stadium Mall Dr.
West Lafayette, IN 47907

Email: dfla...@purdue.edu
Phone: 765-494-4761
Lab Website: www.flahertylab.com
Twitter: @FlahertyLab







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[ccp4bb] Crystallographer Postdoc Position at Purdue University

[Flaherty, Daniel P]

Hello All,

We have new position for a postdoc in X-ray crystallography in the lab of 
Daniel Flaherty in the Department of Medicinal Chemistry and Molecular 
Pharmacology at Purdue University.

The lab is well funded and specializes in drug discovery for antibiotics and 
chronic pain. The successful candidate will work within a highly 
interdisciplinary lab that carries out research within the disciplines of 
high-throughput screening, medicinal chemistry, biochemistry, microbiology and 
structural biology all to support ongoing and newly funding NIH projects.

The current position would work on novel targets for antibiotic drug discovery.

Please see the position and instructions to apply at 
https://www.flahertylab.com/positions

Cheers!

--
Daniel P. Flaherty, PhD
Associate Professor of Medicinal Chemistry
Department of Medicinal Chemistry and Molecular Pharmacology
College of Pharmacy
Purdue University
575 Stadium Mall Dr.
West Lafayette, IN 47907

Email: dfla...@purdue.edu
Phone: 765-494-4761
Lab Website: www.flahertylab.com
Twitter: @FlahertyLab







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[ccp4bb] Post-doctoral position in X-ray crystallography for Drug Discovery

[Flaherty, Daniel P]

The laboratory of Dr. Daniel Flaherty in the Department of Medicinal Chemistry 
and Molecular Pharmacology at Purdue University is seeking a post-doctoral 
research associate in the field of protein X-ray crystallography to support 
drug discovery efforts against a novel antibacterial target of interest in our 
laboratory. Required degree/skills: PhD (or expected PhD) with experience in 
protein crystallography and biophysical techniques with a proven track record 
of successfully solving ligand-bound crystal structures. Required experience 
includes designing plasmids, cloning, mutagenesis, protein preparation, protein 
purification, and a strong background in utilizing PHENIX and COOT or other 
comparable software for structure determination. Desired Skills: Experience 
designing and executing biochemical assays for quantifying protein interactions 
with small molecules, such as with surface plasmon resonance (SPR) or 
isothermal titration calorimetry (ITC). Experience working with bacteria 
including E. faecium, E. faecalis, N. gonorrhoeae and M. smegmatis is a plus.
The candidate would have access to world-class facilities and instrumentation 
to support their work (crystallization drop-setting robots, screen optimization 
robots, plate imaging robots/hotel, walk-in plate incubator rooms, and 
rotating-anode home X-ray sources) within the Crystallography Core located in 
the Hockmeyer Hall of Structural Biology. Synchrotron data collection is also a 
2-hour drive from our laboratory at the Advanced Photon Source (APS) at Argonne 
National Laboratory with remote data collection capabilities. Other 
responsibilities include managing data collection time/trips, maintaining a 
laboratory notebook, assisting graduate students in crystallography, and 
manuscript preparation. This position is funded by a grant from the National 
Institutes of Health in search of novel inhibitors for a new antibacterial 
target. The position offers a competitive salary commensurate upon experience 
plus benefits and is contingent upon meeting progress milestones. The 
successful applicant will be assessed for productivity on a bi-annual basis 
with the option of yearly renewal if agreed upon by both parties.

Interested candidates should submit a cover letter, CV and at least 3 
references that are familiar with the candidate’s experience and research 
potential to https://careers.purdue.edu/job-invite/17056/. The position is open 
immediately, however, start date is flexible and negotiable depending on the 
availability of the candidate. For more information please visit 
https://www.flahertylab.com/positions




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[ccp4bb] Post-Doc opportunity - Flaherty Lab - Purdue University

[Flaherty, Daniel P]

Hello All,

Please find the link below for a post-doc opportunity in X-ray crystallography 
in my lab at Purdue University. This position is supported by recent NIH 
funding.

https://www.flahertylab.com/_files/ugd/16e6c3_7b84e95d2998490096871840f7f4bf39.pdf

Cheers!

/
Daniel P. Flaherty, PhD
Assistant Professor
Department of Medicinal Chemistry and Molecular Pharmacology
Purdue University
(765) 494-4761 | dfla...@purdue.edu
www.flahertylab.com
[signature_763394597]

[signature_1215031315]




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[ccp4bb] NIH Funded Post-Doc Position for X-ray crystallography - Flaherty Lab - Purdue University

[Flaherty, Daniel P]

Post-doctoral Position for Crystallographer to Support Drug Discovery Research



The laboratory of Dr. Daniel Flaherty in the Department of Medicinal Chemistry 
and Molecular Pharmacology at Purdue University is seeking a post-doctoral 
research associate in the field of protein X-ray crystallography to support 
drug discovery efforts against a novel antibacterial target of interest in our 
laboratory. Required degree/skills: PhD (or expected PhD) with experience in 
protein crystallography and biophysical techniques with a proven track record 
of successfully solving ligand-bound crystal structures. Required experience 
includes designing plasmids, cloning, mutagenesis, protein preparation, protein 
purification, and a strong background in utilizing PHENIX and COOT or other 
comparable software for structure determination. Desired Skills: Experience 
designing and executing biochemical assays for quantifying protein interactions 
with small molecules, such as with surface plasmon resonance (SPR) or 
isothermal titration calorimetry (ITC). Experience working with bacteria 
including E. faecium, E. faecalis, N. gonorrhoeae and M. smegmatis is a plus.
The candidate would have access to world-class facilities and instrumentation 
to support their work (crystallization drop-setting robots, screen optimization 
robots, plate imaging robots/hotel, walk-in plate incubator rooms, and 
rotating-anode home X-ray sources) within the Crystallography Core located in 
the Hockmeyer Hall of Structural Biology. Synchrotron data collection is also a 
2-hour drive from our laboratory at the Advanced Photon Source (APS) at Argonne 
National Laboratory with remote data collection capabilities. Other 
responsibilities include managing data collection time/trips, maintaining a 
laboratory notebook, assisting graduate students in crystallography, and 
manuscript preparation. This position is funded by a grant from the National 
Institutes of Health in search of novel inhibitors for a new antibacterial 
target. The position offers a competitive salary commensurate upon experience 
plus benefits and is contingent upon meeting progress milestones. The 
successful applicant will be assessed for productivity on a bi-annual basis 
with the option of yearly renewal if agreed upon by both parties.

Interested candidates should submit a cover letter, CV and at least 3 
references that are familiar with the candidate’s experience and research 
potential to 
https://careers.purdue.edu/job/West-Layayette-Post-Doc-Research-Associate-IN-47906/814628700/?locale=en_US
 . The position is open immediately, however, start date is flexible and 
negotiable depending on the availability of the candidate. For more information 
please visit https://www.flahertylab.com/positions




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[ccp4bb] Post-doctoral research associate in X-ray crystallography at Purdue University

[Flaherty, Daniel P]

Hello All,

My lab is seeking a new post-doc for a recently funded NIH grant for drug 
development of antibiotics against vancomycin resistant enterococcus. The 
project includes a novel therapeutic target that has never before been 
characterized in VRE. We are seeking a post-doc with experience in expression, 
purification and biophysical characterization of novel proteins. This position 
would be an integral part of a drug discovery effort against VRE.

My lab website is flahertylab.com if you would like to 
check out what we do. You can view the position there or apply directly at this 
link: 
https://careers.purdue.edu/job/West-Lafayette-Post-Doc-Research-Associate-IN-47906/599061000/?locale=en_US

The position is open immediately until filled. The start-date is negotiable and 
can be pushed back pending completion of PhD work if necessary.

Cheers,

Dan


/
Daniel P. Flaherty, PhD
Assistant Professor
Department of Medicinal Chemistry and Molecular Pharmacology
Purdue University
(765) 494-4761 | dfla...@purdue.edu
www.flahertylab.com
[signature_247957745]

[signature_1933557592]






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[ccp4bb] Post-doctoral Position for X-ray crystallographer at Purdue University

[Flaherty, Daniel P]

Hello All,

I have a new position for an X-ray crystallography post-doc in my lab at Purdue 
University. This position is on a newly funded NIH grant to support 
structure-based drug discovery against a novel vancomycin-resistant 
enterococcus target that has never been characterized previously. Please see 
the ad below or visit my website to learn more and apply.

Cheers,

Dan Flaherty


Post-doctoral Position for Crystallographer to Support Drug Discovery Research


The laboratory of Dr. Daniel Flaherty in the Department of Medicinal Chemistry 
and Molecular Pharmacology at Purdue University is seeking a post-doctoral 
research associate in the field of protein X-ray crystallography to support 
drug discovery efforts against a novel antibacterial target of interest in our 
laboratory. The ideal candidate would have a PhD (or expected PhD) with 
experience in protein crystallography and a proven track record of successfully 
solving ligand-bound crystal structures. Required experience includes designing 
plasmids, cloning, mutagenesis, protein preparation, protein purification, and 
a strong background in utilizing PHENIX and COOT or other comparable software 
for structure determination. Experience designing and executing biochemical 
assays for quantifying protein interactions with small molecules, such as with 
surface plasmon resonance (SPR), is a plus. The candidate would have access to 
world-class facilities and instrumentation to support their work 
(crystallization drop-setting robots, screen optimization robots, plate imaging 
robots/hotel, walk-in plate incubator rooms, and rotating-anode home X-ray 
sources) within the Crystallography Core located in the Hockmeyer Hall of 
Structural Biology. Synchrotron data collection is also a 2-hour drive from our 
department at the Advanced Photon Source (APS) at Argonne National Laboratory. 
Other responsibilities include managing data collection time/trips, maintaining 
a laboratory notebook, assisting graduate students in crystallography, and 
manuscript preparation. This position is funded by a recently awarded grant 
from the National Institutes of Health in search of novel inhibitors for a new 
antibacterial target. The position offers a competitive salary commensurate 
upon experience plus benefits and is contingent upon meeting progress 
milestones. The successful applicant will be assessed for productivity on a 
bi-annual basis with the option of yearly renewal if agreed upon by both 
parties.

Interested candidates should submit a cover letter, CV and at least 3 
references that are familiar with the candidate’s experience and research 
potential to flahertylab.pur...@gmail.com. 
The position is open November 2019, however, start date is flexible and 
negotiable depending on the availability of the candidate. For more information 
please visit https://www.flahertylab.com/positions




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[ccp4bb] Post-Doc Opportunity

[Flaherty, Daniel P]

Hello All,

I have an Post-Doc opening in my lab for an X-ray crystallographer to support 
our drug development efforts. Please see the ad 
(https://jobs.sciencecareers.org/job/485983/post-doctoral-research-associate-in-x-ray-crystallography/)
 for more information or contact me at dfla...@purdue.edu if you have any 
questions.

Cheers,

Dan



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[ccp4bb] Crystallography/drug development Post-doc opportunity

[Flaherty, Daniel P]

Hello All,

My name is Daniel Flaherty and I am an Assistant Professor at Purdue 
University. I am seeking a post-doc with experience in structural determination 
of protein targets and ligand-bound protein structures to support our drug 
development projects.  Please find the position announcement at this website: 
https://www.flahertylab.com/positions

Cheers,

Dan



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