[ccp4bb] Open postdoc position in protein crystallography at Lisbon, Portugal
Dear all I'd like to draw your attention to the postdoc position in protein crystallography, currently open in my group at UCIBIO-NOVA (Faculty of Science and Technology, NOVA University of Lisbon, Portugal). I am a young PI interested in protein-ligand interactions for structural-based drug design and the Postdoc will be integrated into my research team, currently holding 9 full-time people. The fellowship will be awarded for a period of 12 months, eventually extended using other funding schemes. Candidates should hold a PhD in chemistry, biochemistry or related areas and experience in structural biology. It is mandatory that the candidate has proven know-how in protein cloning, expression and purification, crystallization, data collection, structure determination and model refinement. Preference will be given to candidates with experience in different expression systems (bacterial, yeast, insect and mammalian) and biophysical methods for characterizing protein-ligand interactions. The candidate should be able to develop work autonomously. Work Plan: During the time of the fellowship the candidate will be involved in expression, purification and crystallization of soluble proteins that are important targets for drug development. Biophysical methods will be applied to determine protein-ligand interaction and structure determination will be carried out in the presence of the best hits. Model analysis will allow rationalize the structural determinants that control ligand binding. Application deadline is December 5th . For more information please check the following link: http://www.eracareers.pt/opportunities/index.aspx?task=global&jobId=94638 I am happy to answer all your questions Kind regards teresa PS: sorry for the earlier mail with wrong subject. Unique identifier: 1c293f55-6fac-403e-b737-b1faf2575b77 <http://www.eracareers.pt/opportunities/index.aspx?task=showAnuncioOportunities&jobId=94638&idc=1> *1. Descrição do cargo/posição/bolsa* *1. Job description* -- *Job:* Research Fellowship for a PhD holder *Job/Fellowship Reference:* PTDC/QEQ-MED/1902/2014 *Main research field:* Chemistry *Sub research field:* Biochemistry *Job summary:* One fellowship for a PhD holder is opened under the scope of the project “Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis” / NOVA.ID.FCT – Associação para a Inovação e Desenvolvimento da FCT, (PTDC/QEQ-MED/1902/2014), which is financed by national funds from FCT/MCTES (PIDDAC) *Job description:* *1. Scientific area: *Structural Biology, Biochemistry, Chemistry *2*. *Admission Requirements:* The fellowship is dedicated to candidates holding a PhD in chemistry, biochemistry or related areas and experience in structural biology. It is mandatory that the candidate has proven knowhow in protein cloning, expression and purification, crystallization, data collection, structure determination and model refinement. Preference will be given to candidates with experience in different expression systems (bacterial, yeast, insect and mammalian) and biophysical methods for characterizing protein-ligand interactions. The candidate should be able to develop work autonomously. *3. Work Plan*: During the time of the fellowship the candidate will be involved in expression, purification and crystallization of soluble proteins that are important targets for drug development. Biophysical methods will be applied to determine protein-ligand interaction and structure determination will be carried out in the presence of the best hits. Model analysis will allow rationalize the structural determinants that control ligand binding. 1. *Rules and Regulations::*Law Nr. 40/2004, of 18th August altered and republish by Decree-Law nº 202/2012 of August 27th (Scientific Research Fellow Statute) and altered by the Decree-Law nº233/2012 of October 29th and by the Law nº12/2013 of January 29th. Regulations for Advanced Training and Qualification of Human Resources, I.P in force ( http://www.fct.pt/apoios/bolsas/docs/RegulamentoBolsasFCT2015.pdf*).* 1. *Working location* *and superviror:* The work is to be carried out at the Departament of Chemistry, at Faculdade de Ciências e Tecnologia da Universidade NOVA de Lisboa (FCT-NOVA) under the scientific supervision of Dr. Teresa Santos-Silva. 1. *Fellowship duration*: The fellowship will last for 12 months, scheduled to begin in December 2017. The scholarship contract may be renewed during the project. 1. *Salary and benefits: *The amount of the fellowship corresponds to € 1.495, according to the table of values ??of grants awarded directly by FCT, I.P. in the country (http: // www.fct.pt/apoios/bolsas/valores), and the payment is made monthly by bank transfer. 1. *Selection methodology*: The candidates will be evaluated according to their CV (40%) and proven lab experience (60%). In case of a ti
[ccp4bb] Fwd: divulgacao bolsa, obrigada
Dear all I'd like to draw your attention to the postdoc position in protein crystallography, currently open in my group at UCIBIO-NOVA (Faculty of Science and Technology, NOVA University of Lisbon, Portugal). I am a young PI interested in protein-ligand interactions for structural-based drug design and the Postdoc will be integrated into my research team, currently holding 9 full-time people. The fellowship will be awarded for a period of 12 months, eventually extended using other funding schemes. Candidates should hold a PhD in chemistry, biochemistry or related areas and experience in structural biology. It is mandatory that the candidate has proven know-how in protein cloning, expression and purification, crystallization, data collection, structure determination and model refinement. Preference will be given to candidates with experience in different expression systems (bacterial, yeast, insect and mammalian) and biophysical methods for characterizing protein-ligand interactions. The candidate should be able to develop work autonomously. Work Plan: During the time of the fellowship the candidate will be involved in expression, purification and crystallization of soluble proteins that are important targets for drug development. Biophysical methods will be applied to determine protein-ligand interaction and structure determination will be carried out in the presence of the best hits. Model analysis will allow rationalize the structural determinants that control ligand binding. Application deadline is December 5th . For more information please check the following link: http://www.eracareers.pt/opportunities/index.aspx?task=global&jobId=94638 I am happy to answer all your questions Kind regards teresa Unique identifier: 1c293f55-6fac-403e-b737-b1faf2575b77 <http://www.eracareers.pt/opportunities/index.aspx?task=showAnuncioOportunities&jobId=94638&idc=1> *1. Descrição do cargo/posição/bolsa* *1. Job description* -- *Job:* Research Fellowship for a PhD holder *Job/Fellowship Reference:* PTDC/QEQ-MED/1902/2014 *Main research field:* Chemistry *Sub research field:* Biochemistry *Job summary:* One fellowship for a PhD holder is opened under the scope of the project “Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis” / NOVA.ID.FCT – Associação para a Inovação e Desenvolvimento da FCT, (PTDC/QEQ-MED/1902/2014), which is financed by national funds from FCT/MCTES (PIDDAC) *Job description:* *1. Scientific area: *Structural Biology, Biochemistry, Chemistry *2*. *Admission Requirements:* The fellowship is dedicated to candidates holding a PhD in chemistry, biochemistry or related areas and experience in structural biology. It is mandatory that the candidate has proven knowhow in protein cloning, expression and purification, crystallization, data collection, structure determination and model refinement. Preference will be given to candidates with experience in different expression systems (bacterial, yeast, insect and mammalian) and biophysical methods for characterizing protein-ligand interactions. The candidate should be able to develop work autonomously. *3. Work Plan*: During the time of the fellowship the candidate will be involved in expression, purification and crystallization of soluble proteins that are important targets for drug development. Biophysical methods will be applied to determine protein-ligand interaction and structure determination will be carried out in the presence of the best hits. Model analysis will allow rationalize the structural determinants that control ligand binding. 1. *Rules and Regulations::*Law Nr. 40/2004, of 18th August altered and republish by Decree-Law nº 202/2012 of August 27th (Scientific Research Fellow Statute) and altered by the Decree-Law nº233/2012 of October 29th and by the Law nº12/2013 of January 29th. Regulations for Advanced Training and Qualification of Human Resources, I.P in force ( http://www.fct.pt/apoios/bolsas/docs/RegulamentoBolsasFCT2015.pdf*).* 1. *Working location* *and superviror:* The work is to be carried out at the Departament of Chemistry, at Faculdade de Ciências e Tecnologia da Universidade NOVA de Lisboa (FCT-NOVA) under the scientific supervision of Dr. Teresa Santos-Silva. 1. *Fellowship duration*: The fellowship will last for 12 months, scheduled to begin in December 2017. The scholarship contract may be renewed during the project. 1. *Salary and benefits: *The amount of the fellowship corresponds to € 1.495, according to the table of values ??of grants awarded directly by FCT, I.P. in the country (http: // www.fct.pt/apoios/bolsas/valores), and the payment is made monthly by bank transfer. 1. *Selection methodology*: The candidates will be evaluated according to their CV (40%) and proven lab experience (60%). In case of a tie, an interview will be requested and the final g
[ccp4bb] post-doc position @ Portugal on drug-design
The Associate Laboratory REQUIMTE-CQFB, from Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa (https://www.fct.unl.pt/en) is opening a post-doc position to integrate a multidisciplinary team in Structural Biology. The applicant must have a PhD in biochemistry, biology or related fields and preference will be given to demonstrated experience in protein crystallography and small molecules crystallography. Contract: Initial duration is 3 months, renewable for additional 12 months, with starting date predicted for 1st of September of 2013. Monthly Stipend: According to the amounts stipulated by FCT (www.fct.pt) for Research Grants in Portugal - 1495,00€ Job description: The main purpose of the work is to structurally characterize at the molecular level the interaction of plasma proteins (human serum albumin and human transferrin) with potential drugs (CORMs). These are CO releasing molecules that have demonstrated therapeutic effects in several models of disease (inflammation, apoptosis, cell proliferation, among others) (Santos-Silva, JACS 2011, Curr Med Chem 2011; Santos, J Inorg Biochem 2012; Seixas, Dalton Trans. 2012). Biochemical and crystallographic studies, in combination with theoretical calculations, will be performed, in the Protein Crystallography lab of the Chemistry Department from Faculdade de Ciências e Tecnologia of Universidade Nova de Lisboa (Lisbon-Caparica, Portugal) under the supervision of Doctor Teresa Santos Silva and Prof. Maria João Romão ( http://xtal.dq.fct.unl.pt). The work is part of an on-going collaboration with Prof. Carlos Romão from ITQB-UNL(Oeiras, Portugal) (www.itqb.unl.pt), and the Pharmaceutical company Alfama. Deadline for application: 15 July 2013 Applications should include: motivation letter, Curriculum Vitae, names and emails of 2 possible referees, copy of the degree certificate as well as other documents considered to be relevant, and sent to Dr Teresa Santos-Silva, t...@fct.unl.pt. Please go to the following website to find about further details on this application and project: http://www.eracareers.pt/opportunities/index.aspx?task=global&jobId=37399 Applications must be sent to t...@fct.unl.pt
