[ccp4bb] Instruct Biennial Structural Biology Conference: Last Chance to Register

[ccp4mail]

Dear all,


There are a few final spaces available to register for the Instruct Biennial 
Structural Biology Conference 2024 – book 
your spot by 3 May.





Register Here





The 23-24 May conference will feature talks from expert speakers in integrated 
structural biology – see the full list of speakers below.



As well as talks, the conference will include poster sessions with the latest 
new developments in structural biology, as well as the Gala Dinner and 
networking opportunities.



Make sure you book your spot before time runs out 3 
May.





Speaker List

[https://instruct-eric.org/upload/uoChSIvcItLnOpEScqbEa0fJbQYN06AZ.png]



Kind regards,

Instruct-ERIC



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Instruct-ERIC Structure Meets Function Webinar 32

[ccp4mail]

Register now for the 32nd edition of the Instruct-ERIC Structure Meets Function 
webinar 
series,
 taking place on Zoom, 17 April at 11:00 CEST.





Register 
Here





The latest webinar will have two speakers who have accessed the Instruct-ERIC 
facilities, expertise, and machinery via the ISIDORe project.



Talk 1: Nikitas Georgiou - National and Kapodistrian University of Athens
Title: Potential anti-inflammatory drugs



Talk 2: Séverine Padiolleau - Université de Technologie de Compiègne
Title: Identification of aptamers interacting with a protein target involved in 
lyme disease


Read the full talk abstracts and register for the webinar 
here.





[https://instruct-eric.org/upload/bPEETiDbLkqAYuMtVkEgCUz85k143gkA.jpg]



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Structure Meets Function Webinar #31

[ccp4mail]

Dear All,

Register now for the 31st edition of the Instruct-ERIC Structure Meets Function 
webinar series, taking place on Zoom, 19 March at 11:00 
CET





Register 
Here



The latest webinar in the Instruct-ERIC Structure Meets Function series is 
hosted by Instruct-FR2. The webinar series offers an insight into the very 
cutting edge of structural biology research, utilising the latest techniques 
available through Instruct-ERIC facilities and centres.


Speaker 1: Vincent Chaptal - Institut de Biologie et Chimie des Protéines, Lyon

Title: Plasticity in the mutidrug ABC transporter BmrA as a base to handle 
multiple substrates, and how substrates can modulate it for a more efficient 
use of ATP.

Speaker 2: Barbara Zambelli - Università di Bologna


Title: Dissecting the structure of the nickel binding site of HypA•UreE2 
complex required for urease maturation.


Read the full talk abstracts and register for the webinar 
here.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Fw: R and TechDev Funding Calls Open for 2024

[ccp4mail]

Dear all,


Time is running out to apply for the Instruct R Funding Call, and TechDev 
Call. The R call is open to early career researchers, whilst the TechDev call 
is designed for researchers with a proven track record in technology and 
methods development. Find out more and apply below!


Researchers working on all methods in integrated structural biology are invited 
to apply.



R Funding Call



The Instruct-ERIC R Funding Call for 2024 is now open. Early career 
researchers are invited to submit proposals to access Instruct technology, 
equipment, and expertise from our 27 facilities across Europe for small scale 
pilot research projects in integrated structural biology.



This call is open to all topics within integrated structural biology and offers 
funding of up to a maximum of €15,000 per project. The call will close 15 March 
2024, so submit your 
application soon.



Apply to R Call Here



TechDev Call



The new Instruct Technology Development Call is aimed at researchers with a 
proven track record in technology and methods development. This call is open 
for two specific topics for structural biology technology development:

  *   Sample Preparation
  *   Data Management

Get more info on the topics here.


The TechDev call offers funding of up to €30,000 for pilot projects.



Apply to TechDev Call Here




Find out more about the criteria for each call 
here.


Kind regards

Instruct-ERIC Hub Team




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] R and TechDev Funding Calls Open for 2024

[ccp4mail]

Dear all,


This is a reminder to apply for the Instruct-ERIC R Pilot Call, and brand new 
TechDev Call!



R Funding Call



The Instruct-ERIC R Funding Call for 2024 is now open. Early career 
researchers are invited to submit proposals to access Instruct technology, 
equipment, and expertise from our 27 facilities across Europe for small scale 
pilot research projects in integrated structural biology.



This call is open to all topics within integrated structural biology and offers 
funding of up to a maximum of €15,000 per project. The call will close 15 March 
2024, so submit your 
application soon.



Apply to R Call Here



TechDev Call



The new Instruct Technology Development Call is aimed at researchers with a 
proven track record in technology and methods development. This call is open 
for two specific topics for structural biology technology development:

  *   Sample Preparation
  *   Data Management

Get more info on the topics here.


The TechDev call offers funding of up to €30,000 for pilot projects.



Apply to TechDev Call Here




Find out more about the criteria for each call 
here.


Kind regards

Instruct-ERIC Hub Team




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Structure Meets Function #30

[ccp4mail]

Dear All,

Register now for the 30th edition of the Instruct-ERIC Structure Meets Function 
webinar series, taking place 14:00 GMT on 13 February.

Register 
Here.

Structure Meets Function showcases the latest structural biology research and 
technology development, from Instruct centres and beyond! This month, speakers 
from Fragment-Screen will be giving 
a talk, outlining their machine learning research and how that fits to 
fragment-based drug discovery, and the wider structural biology field.

Speaker 1: Beatriz Serrano-Solano, Euro-BioImaging
Introduction to AI4Life Open Call

Speaker 2: Tiago Rodrigues, FFUlisboa

Speaker 3: Enara Vijil, IBM

Find out more and register 
here.

Kind regards,
Instruct-ERIC Hub Team



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Instruct webinar_Structure meets function today at 11am CET

[ccp4mail]

Register now for the 29th edition of the Instruct-ERIC Structure Meets Function 
webinar series, taking place 11:00 CET on 23 
January.





Register Here





Structure Meets Function showcases the latest structural biology research and 
technology development, from Instruct centres and beyond! This month, 
Instruct-FR1 will host the webinar. Find out more about the services available 
at IGBMC here.



Speaker 1: Katia Zanier - Université de Strasbourg
Title: Mechanism of IKK kinase-substrate docking in NF-kB signaling





Speaker 2: Konstantin Brodolin - Université de Montpellier
Title: Regulation of transcription via RNA polymerase oligomerization



Read the full talk abstracts and register for the 
 
webinar 
 
here.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Instruct-ERIC Structure Meets Function Webinar 29

[ccp4mail]

Dear all,


Register now for the 29th edition of the Instruct-ERIC Structure Meets Function 
webinar series, taking place 11:00 CET on 23 
January.





Register Here 






Structure Meets Function showcases the latest structural biology research and 
technology development, from Instruct centres and beyond! This month, 
Instruct-FR1 will host the webinar. Find out more about the services available 
at IGBMC here.



Speaker 1: Katia Zanier - Université de Strasbourg
Title: Mechanism of IKK kinase-substrate docking in NF-kB signaling





Speaker 2: Konstantin Brodolin - Université de Montpellier
Title: Regulation of transcription via RNA polymerase oligomerization



Read the full talk abstracts and register for the webinar 
here.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Instruct Biennial Structural Biology Conference 2024 - Cascais, Portugal

[ccp4mail]

Dear,


The Instruct Biennial Structural Biology 
Conference is open for registration – book 
your spot at the conference and secure your accommodation!




Register Here





The conference will feature more than 20 expert speakers in integrated 
structural biology – all fields will be covered including Cryo-EM, NMR, X-ray 
techniques, mass spectrometry, as well as artificial intelligence and more!



Taking place 23-24 May 2024, the venue for the conference is the Hotel Citadela 
in Cascais, Portugal. You can book your accommodation at the 
hotel too, for quick access to the 
conference.





[https://instruct-eric.org/upload/v4RrRm4pzVBC2xGM9UM6A5KalHaaGXvT.jpeg]





As well as great talks, the conference 
agenda also includes poster 
sessions, and the gala dinner. Abstracts submitted for the poster sessions may 
be selected to give full talks during the plenary session.



Find out more about the conference and register 
here.


Kind regards,

Instruct-ERIC



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] canSERV Open Call - Get Funded Access to Structural Biology Technology for Cancer Research

[ccp4mail]

Dear All,

The canSERV Call for Transnational Service 
Provision is now open.

Funded access to structural biology is available for researchers worldwide, for 
projects with a cancer-related topic.

Running until 4 January 2024, the call offers the opportunity for researchers 
to access all Instruct services for their cancer research.

The research project can vary from basic discovery science to translational 
science and translation into personalised oncology, and is expected to address 
at least one of the four strategic goals of the Cancer Mission:

  *   Understanding of cancer
  *   Prevention and early detection
  *   Diagnosis and treatment
  *   Quality of life for patients and their families

If granted, researchers will benefit from: Free of charge access to canSERV 
service(s) (equipment, expertise, resources) offered by the canSERV consortium.

Find out more about the call and apply 
here.
[https://instruct-eric.org/upload/BLaiQI9MULtvkIRgadYCQ9GxEiQ6bNcz.png]
canSERV Open Call
Instruct-ERIC is a pan-European research infrastructure in structural biology, 
making high-end technologies and methods available to all European researchers.
instruct-eric.org




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Structure Meets Function Webinar #28 - Instruct-FI

[ccp4mail]

Dear all,

Registration is open for the 28th 
edition of 
the Structure Meets Function webinar from Instruct-ERIC. The 
webinar
 will take place 17 October 2023 at 11:00 CET (10:00 GMT).

This month will be hosted by Instruct-FI, with fantastic speakers who have 
accessed Instruct facilities in Finland!

The webinar series showcases the very cutting-edge of structural biology, and 
demonstrates the work that can be done with access to advanced equipment and 
expertise. Take a look at our previous webinars in the series here. 



Speaker 1: Ilona Rissanen - University of Helsinki

Speaker 2: Giovanna Viola - University of Verona

Register 
here

We look forward to seeing you at the webinar!
Instruct-ERIC Hub



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Ivano Bertini Award Nominations Now Open_Reward scientific excellence in the field of integrated structural biology

[ccp4mail]

Dear all,


The Bertini Award 2024 call is open, 
submit your nominations for the winner before the deadline of 30 September 2023.



Nominations are invited for the Award for a significant achievement in any area 
of integrated structural biology. Self-nominations are not accepted.



Ivano Bertini was a pioneer of innovative methodologies in the field of NMR 
spectroscopy who championed technology integration as a foundation for 
correlative structural biology. Instruct-ERIC presents an award in his name at 
the Biennial Structural Biology 
Conference, recognising scientists who 
have undertaken frontier research utilising an integrative structural biology 
approach which aligns with the Instruct vision.



The award will be given solely on the basis of excellence in research and must 
include structural data as a key component of the research achievement. The 
award recognises a clearly defined breakthrough (either in scientific knowledge 
or technology development) and is not for a lifetime achievement.


Submit your nominations here.



Take a look at the winner of last year's award, Sjors Scheres, 
here.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Register now! Instruct-ERIC webinar 13 June 2023 11 CEST

[ccp4mail]

Dear all

Register now for the 27th Structure Meets Function 
webinar from Instruct-ERIC. The 
webinar will take place 13 June 2023 at 11:00 CEST (10:00 GMT).



This month will feature 3 excellent speakers who have accessed Instruct 
centres, specifically the Robotein institution in Belgium, and two EMBL 
facilities.



Take a look at our previous webinars in the series 
here.





Register Here





Speaker 1: Daphnée Georges, ULB; Marylène Vandevenne, Robotein

Talk Title: Analysing COVID-19 vaccine responses at Robotein



Speaker 2: Maria Dimarogona, University of Patras

Talk Title: Structural insights into carbohydrate-active enzymes for the design 
of plastic degrading biocatalysts



Speaker 3: Leonardo Alonso, University of Buenos Aires

Talk Title: Behind the functional role of asparagine deamidation in coronavirus 
proteins




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Reminder: Registration open: Structure Meets Function Webinar #26 -16 May_ New Technologies in Instruct 16 May

[ccp4mail]

Dear all,


Registration is 
open for 
the 26th edition of the Structure Meets Function 
webinar
 from Instruct-ERIC. The webinar will take place 16 May 2023 at 11:00 CEST 
(10:00 GMT).



This month will feature 4 speakers from across the Instruct-ERIC catalogue: two 
from CNB-CSIC in Madrid, Spain, and two from IGBMC of Instruct-FR2, in 
Strasbourg, France. Find out more about the webinar and register 
here.



Take a look at our previous webinars in the series 
here.





Register 
Here





Speaker 1: Javier Conesa

Speaker 2: David Herreros

Talk Title: Introduction to CNB-CSIC CLEM, and I2PC FlexiHub.



Speaker 3: Alexandre Durand

Speaker 4: Catherine Birck

Talk Title: Introduction to IGBMC Chameleon and BLI/FIDA.








To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Registration open: Structure Meets Function Webinar #26 - New Technologies in Instruct

[ccp4mail]

Dear all,


Registration is 
open for 
the 26th edition of the Structure Meets Function 
webinar
 from Instruct-ERIC. The webinar will take place 16 May 2023 at 11:00 CEST 
(10:00 GMT).



This month will feature 4 speakers from across the Instruct-ERIC catalogue: two 
from CNB-CSIC in Madrid, Spain, and two from IGBMC of Instruct-FR2, in 
Strasbourg, France. Find out more about the webinar and register 
here.



Take a look at our previous webinars in the series 
here.





Register 
Here





Speaker 1: Javier Conesa

Speaker 2: David Herreros

Talk Title: Introduction to CNB-CSIC CLEM, and I2PC FlexiHub.



Speaker 3: Alexandre Durand

Speaker 4: Catherine Birck

Talk Title: Introduction to IGBMC Chameleon and BLI/FIDA.








To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Register now_Instruct Webinar Structure Meets Function #25_14 March 11am CET

[ccp4mail]

Registration
 is now open for the 25th edition of the Structure Meets Function 
webinar
 from Instruct-ERIC. The webinar will take place 14 March 2023 at 11:00 CET 
(10:00 GMT).



This month will feature two great speakers from the Instruct-CZ Centre: Tibor 
Fuzik of CEITEC, and Ondrej Vanek of Charles University. Join us for fantastic 
insight into how Instruct-ERIC access to facilities can advance structural 
biology research.





Register 
Here





Speaker 1: Tibor Fusik

Talk Title: Structure of tick-borne encephalitis virus immature particle solved 
by cryo-electron microscopy and sub-tomogram averaging.



Speaker 2: Ondřej Vaněk

Talk Title: Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex 
reveals clustering in the immune synapse.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Register Now: Instruct-ERIC Structure Meets Function Webinar - 13 December 3PM CET

[ccp4mail]

Dear all,

Registration is now open for the 23rd edition of the Structure Meets Function 
webinar from Instruct-ERIC. The 
webinar will take place 13 December 2022 at 12:00 ART (15:00 CET).



This month will feature two excellent speakers, both from IBR-CONICET: Leticia 
Llarrull and Alejandro Vila. Both speakers participated in Instruct-ERIC's 
international call for access, which 
was open for researchers from institutions that hold an MOU with Instruct to 
access the European facilities.





Register Here





Moderator: Ana Zeri, LNLS



Speaker 1: Leticia Llarrull, IBR-CONICET

Talk Title: Advances in structural and functional characterization of the 
sensor/transducer MecR1 protein of Staphylococcus aureus

Abstract: Methicillin resistant Staphylococcus aureus (MRSA) is a pathogen that 
poses a worldwide threat. Resistance to β-lactams in MRSA is inducible, and 
MecR1 regulates expression of PBP2a, the main resistance determinant. We are 
interested in unveiling how the presence of β-lactams activate this 
metalloprotease, resulting in manifestation of resistance, and on understanding 
the functional differences with its homologue, BlaR1 from S. aureus, which 
regulates expression of a serin-β-lactamase. To date, no high-resolution model 
of full-length MecR1 or BlaR1 is available.



Speaker 2: Alejandro Vila, IBR-CONICET

Talk Title: In-cell kinetic stability is an essential trait in protein 
evolution: the case of Metallo-beta-lactamases

Abstract: Protein stability is essential for biological function. In contrast 
to the vast knowledge on the thermodynamics of protein stability in vitro, 
little is known about the factors governing the in-cell stability, that defines 
the lifetime of the native state of proteins within the cell. Here we show that 
the kinetic stability of the metallo-β-lactamase NDM-1 in the bacterial 
periplasm is optimized to face metal restriction at the host-pathogen 
interface. NDM-1 is one of the main responsible of providing resistance to 
carbapenems in pathogenic bacteria. Despite its high stability in vitro, the 
non-metalated (apo) NDM-1 is unstable in the bacterial periplasm. NMR reveals 
that metal dissociations endows the apo-enzyme with flexibility at the 
C-terminal helices, that enable recognition by specific periplasmic proteases, 
or to aggregation. Zn(II) binding renders the protein refractory to degradation 
by quenching this flexibility. Apo-NDM-1 is anchored to the outer membrane, a 
localization that renders it less accessible to the proteases and less prone to 
aggregate. More recent clinical variants of NDM accumulate mutations that 
quench this flexibility therefore enhancing their stability towards 
proteolysis. This work provides direct evidence of how the kinetic stability of 
a protein optimized within the bacterial cell, and links 
metallo-β-lactamase-mediated resistance with the cellular metabolism in the 
periplasm. In cell NMR also reveals information on the degradation pathway, 
providing insights into the physiology of the bacterial periplasm

Reply
Forward
C




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] 4 new calls for access to Instruct and other Research Infrastructures for research projects on a broad range of pathogens

[ccp4mail]

Dear all,

The ISIDORe Project has opened four 
new calls, providing transnational 
access for structural biology researchers, (and researchers in other fields of 
science) working on Infectious disease research. The new calls will focus on 
these 4 topics:



• Risk Group 4 Pathogens
• Respiratory Pathogens
• Vector-Borne Pathogens and Their Vectors
• Other Pathogens with Epidemic Potential



Applications are now open for all four calls. Each call has an open deadline as 
long as funding remains.





Apply for Access





ISIDORe offers funded transnational access for researchers in a range of 
research fields, including structural biology. Find out more about the services 
available to access here.



Find out more about the requirements for each call here, and apply 
now!


Please contact us if you have any question 
regarding ISIDORe calls and the application process at 
isid...@instruct-eric.org

[https://instruct-eric.org/upload/e2xJvxfH8KdlKT2XdGPEEp4aI5s4p3OA.png]




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Instruct webinar Structure Meets Function - Webinar #22 - Registration Open!

[ccp4mail]

Dear all,


Featuring expert speakers from Instruct Centres across Europe and Instruct 
international partner Institutions, the Instruct-ERIC webinar series,Structure 
Meets 
Function,
 highlights some of the latest developments in structural biology, 
demonstrating how integrative methods are enabling scientists to decipher the 
mechanisms that underpin health and disease.





Register 
Here





Registrationis
 now open for the 22nd webinar in the series on12 October 2022, 3pm CEST(2:00pm 
BST, 10:00am BRT). This webinar will be led by guest speakers fromInstruct's 
partner institutions in Latin 
America. The 
invited speakers will give talks on the work they completed as part of the 
Instruct International Call.

The upcoming webinar will feature talks on the use of Crystallography, 
biophysical techniques, Cryo-EM, X-Ray and NMR to investigate Septin's 
structure and function.






Moderator: Maria Natalia Lisa, Instituto de Biología Molecular y Celular de 
Rosario, Argentina



Talk 1:Protein crystallography off the beaten track: Septins, their filaments 
and the importance of access to research infrastructure
Speaker:Richard Garratt, University of Sao Paulo, Brazil



Talk 2:The versatile septin coiled-coil domains
Speaker:Italo Cavini, University of Sao Paulo, Brazil



You canview the full abstracts and 
registeron
 the Instruct-ERIC website, where you can also watch recordings of theprevious 
webinars.







To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Structure Meets Function Webinar #21 - The New Antibiotic Teixobactin!

[ccp4mail]

Dear all,


Instruct-ERIC is delighted to welcome Markus Weingarth of the Bijvoet Centre, 
Utrecht University to 
speak at the latest Structure Meets Function webinar!






Register Here 







Markus is author and lead on the spectacular new paper "Teixobactin kills 
bacteria by a two-pronged attack on the cell 
envelope"
 (Shukla et al, 2022), which has delved deep into the function and mechanism by 
which this new antibiotic attacks the bacterial cell envelope.



The webinar will take place 11:00 - 12:00 CEST. Register for the webinar 
here.



Moderator: Prof Harald Schwalbe, Instruct-ERIC 
Director



Speaker: Markus Weingarth, Associate Professor at Bijvoet 
Centre



Abstract: The group of Markus Weingarth studies the mode of action of 
membrane-active antibiotics on several length scales (micrometre to angstrom) 
using solid-state NMR as core technique. This talk will focus on the recent 
discovery of the supramolecular killing mechanism of the antibiotic teixobactin 
(Shukla et al., Nature, 2022).



[https://instruct-eric.org/upload/5PZuEoj8HSteLHbt9jTNIHepb0j7Kq5S.png]




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Get funding for Monkeypox research projects to access Instruct-ERIC structural biology services via ISIDORe

[ccp4mail]

1) Launch of emergency call for proposals on Monkeypox virus

ISIDORe just launched a call for transnational access for projects focusing on 
Monkeypox research.



Get access free of charge to cutting-edge services & technologies for 
structural biology and other services via ISIDORe.



ISIDORe supports access free of charge which includes logistical, technological 
and scientific support and, when appropriate, the specific training that is 
needed to use the services provided by the research facilities. Contribution to 
travel, accommodation and sample shipping will be offered.





Start your Pre Application here





  *   All scientists from Academia and Industry from European and non-European 
countries are eligible for this call.
  *   This call supports transnational access: scientists can only apply to 
services outside of their country of residence.
  *   The call supports physical, remote and virtual access to ISIDORe services
  *   The deadline for pre-application to this call is 05 August 2022, 23:59 
CEST



[cid:c029e61a-5183-439f-862d-adc1a9e47aeb]



Application process:

1) Fill in the pre-application form at the bottom of the Monkeypox call 
page (you will need an 
ORCID number to apply to this call)
2) You will receive an email with an ISIDORe ID number and a second email with 
a link towards the structural biology services application page.
3) On the application page, select the structural biology service(s) that you 
want to use, and apply for access via ARIA. You will need to provide the 
ISIDORe ID number in your application.

Get additional information about ISIDORe and the transnational calls on our 
ISIDORe help page

If you have any questions regarding ISIDORe and the call application process:





Contact Us




2) Ongoing SARS-COV-2 & Covid-19 call for proposals

The ISIDORe call for proposals focused on SARS-CoV-2 is still open for 
applications.





Start your Pre Application here




3) ISIDORe Information Webinar



The ISIDORe coordination team is launching the first in a series of webinars to 
provide information about ISIDORe initiative, its open calls for proposals 
dedicated to SARS-CoV-2/COVID-19 and Monkeypox virus, and how to apply to 
services. The first webinar will be held on 12th July 2022, 10:00-11:30 AM CEST.





Register to the webinar here





[cid:090812ec-4ae9-4a8d-9b56-e8201387f1d3]




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Get funding to access Instruct-ERIC structural biology services via ISIDORe

[ccp4mail]

 Dear all,


ISIDORe launched the first call for transnational access for projects focusing 
on SARS-CoV-2 research.

Get access free of charge to cutting-edge services & technologies for 
structural biology and other services via ISIDORe.

ISIDORe supports access free of charge which includes logistical, technological 
and scientific support and, when appropriate, the specific training that is 
needed to use the services provided by the research facilities. Contribution to 
travel, accommodation and sample shipping will be offered.


Start your Pre Application 
here

  *   All scientists from Academia and Industry from European and non-European 
countries are eligible for this call.
  *   This call supports transnational access: scientists can only apply to 
services outside of their country of residence.
  *   The call supports physical, remote and virtual access to ISIDORe services
  *   The call will remain open as long as funding is available

[cid:3917691e-3764-4b90-8a38-bfa09358b428]



Application process:

1) Select your structural biology service of interest on the ISIDORe 
website
2) Fill in the pre-application form at the bottom of the service page (you will 
need an ORCID number to apply to this call)
3) You will receive an email with an ISIDORe ID number and a second email with 
a link towards the structural biology services application page.
4) On the application page, select the structure biology service(s) that you 
want to use, and apply for access via ARIA. You will need to provide the 
ISIDORe ID number in your application.


Get additional information about ISIDORe and the 1st transnational call on our 
ISIDORe help 
page.
 If you have any questions regarding ISIDORe and the call application process:


Contact Us




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Instruct-ERIC webinar Structure Meets Function#20 _ Registration Open

[ccp4mail]

 
Registration
 is now open for the 20th webinar in the series, which will be hosted by 
Instruct Centre 
UK on 7 
June 2022, 11:00 - 12:30 CEST. The upcoming webinar will feature talks on the 
use of CryoEM and symmetry expansion to investigate the structure and function 
of key protein complexes of high impact in the field of Synthetic Biology and 
Agronomy.



Moderator: Joshua White, University of Leeds



Talk 1: Understanding the mechanism of the bifurcating hydrogenase from 
Thermotoga maritima through the application of cryoEM and symmetry expansion
Speaker: Jamie Blaza



Talk 2: Structure and mechanism of action of Vip3 toxins
Speaker: Colin Berry



You can view the full abstracts and 
register
 on the Instruct-ERIC website, where you can also watch recordings of the 
previous 
webinars.





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Register Now for Structure Meets Function Webinar 19 - Instruct-Spain-10th May

[ccp4mail]

Dear all,



Registration is now open for the 19th 
webinar in the series, which will be hosted by Instruct Centre 
Spain on 10 May 2022, 11:00 - 12:30 
CEST. The upcoming webinar will feature talks on the use of NMR Bioreactors for 
in-cell metabolite profiling, cellular signalling and the structure of membrane 
proteins, and exploring viral genome delivery



Talk 1: Characterisation of the Chikungunya virus nsP1 RNA capping pathway 
using the cryoEM facilities at Instruct CNB

Speaker: Rhian Jones



Talk 2: From Structure to Function and Back - identifying a medically crucial 
membrane protein by CryoEM

Speaker: Simone Weyand



Talk 3: Visualizing key regulatory allosteric mechanisms in bacterial glycogen 
biosynthesis

Speaker: Javier Cifuente



You can view the full abstracts and 
register on the Instruct-ERIC website, 
where you can also watch recordings of the previous 
webinars.


Best Regards

​



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Instruct webinar Structure meets function- webinar #18- registration open

[ccp4mail]

 Dear all,



Registration is now open for the 18th 
webinar in the series, which will be hosted by Instruct Centre 
Netherlands on 12 April 2022, 11:00 - 
12:30 CEST. The upcoming webinar will feature talks on the use of NMR 
Bioreactors for in-cell metabolite profiling, cellular signalling and the 
structure of membrane proteins, and exploring viral genome delivery



Talk 1: A Real-Time Approach to Study Cellular Metabolism in Hepatocytes
Speaker: Simone Fjordside



Talk 2: Reconstituting the 2D world of signalling proteins – exploring the role 
of membrane topography for information transfer
Speaker: Kristina Ganzinger



Talk 3: Structure of a proteo-lipidic viral tail-tube for viral genome delivery
Speaker: Nicola Abrescia



You can view the full abstracts and 
register on the Instruct-ERIC website, 
where you can also watch recordings of the previous 
webinars.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Instruct webinar Structure meets function- webinar #17- registration open

[ccp4mail]

Dear all,

Featuring expert speakers from Instruct Centres across Europe, the 
Instruct-ERIC webinar series, Structure Meets 
Function,
 highlights some of the latest developments in structural biology, 
demonstrating how integrative methods are enabling scientists to decipher the 
mechanisms that underpin health and disease.





Register 
Here






Registration
 is now open for the 17th webinar in the series, which will be hosted by 
Instruct Centre Italy 

 on 15 March 2022, 11:00 - 12:00 CET. The upcoming webinar will feature talks 
on the use of NMR Bioreactors for in-cell metabolite profiling, the 
mitochondrial protein biogenesis, and using isothermal titration calorimetry to 
analyse proteins involved in lung cancer progression.



Talk 1: A Real-Time Approach to Study Cellular Metabolism in Hepatocytes
Speaker: Simone Fjordside



Talk 2: Novel interaction between the key mitochondrial oxidoreductase Mia40 
and the major thiol peroxidase Gpx3
Speaker: Kostas Tokatlidis



Talk 3: Characterization of the intrinsically disordered region of human N-myc 
downstream regulated gene-1, a possible target for lung cancer therapy
Speaker: Barbara Zambelli



You can view the full abstracts and 
register
 on the Instruct-ERIC website, where you can also watch recordings of the 
previous 
webinars.







To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Register Now - Instruct-ERIC Webinar Series: Structure Meets Function #16

[ccp4mail]

Dear all,


Featuring expert speakers from Instruct Centres across Europe, the 
Instruct-ERIC webinar series, Structure Meets 
Function,
 highlights some of the latest developments in structural biology, 
demonstrating how integrative methods are enabling scientists to decipher the 
mechanisms that underpin health and disease.





Register 
Here







Registration
 is now open for the 16th webinar in the series, which will be hosted by 
Instruct Centre Israel  on 8 
February 2022, 11:00 - 12:00 CET. The upcoming webinar will feature talks on 
the application of in-vitro evolution and Cryo-EM to study the emergence of 
SARS-CoV-2 variants and discuss the use of AI-based modelling software, such as 
AlphaFold in protein optimisation.



Talk 1: SARS-CoV-2 Omicron prediction and antiviral drug design are enabled by 
RBD in vitro evolution
Speaker: Gideon Schreiber



Talk 2: AlphaFold and protein optimisation
Speaker: Sarel Fleishman



You can view the full abstracts and 
register
 on the Instruct-ERIC website, where you can also watch recordings of the 
previous 
webinars.



We hope that you can join the webinar - please feel free to share this message 
with anyone who might be interested in attending.

Best Regards,

The Instruct hub team



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Register Now - Instruct-ERIC Webinar Series: Structure Meets Function #15

[ccp4mail]

Dear all,

Featuring expert speakers from Instruct Centres across Europe, the 
Instruct-ERIC webinar series, Structure Meets 
Function, highlights some of the 
latest developments in structural biology, demonstrating how integrative 
methods are enabling scientists to decipher the mechanisms that underpin health 
and disease.





Register Here





Registration is open for the 15th 
webinar in the series, which will be hosted by Instruct Portugal on 14th 
December 2021, 11:00 - 12:30 CET. The upcoming webinar will feature talks on 
the application of structural biology methods to better understand key aspects 
of protein complexes structure and function. The webinar speakers will discuss 
new drug targets for diseases, with a focus on Mycobacterium tuberculosis. 
Additional topics include structural biology techniques with Mass Spectrometry 
and Cryo-EM.



  *   Talk 1: Exploring a new drug target against Mycobacterium tuberculosis

Speaker: Hugo Fraga
  *   Talk 2: Breaking the limits of native MS with MRMS
Speaker: Carlos Cordeiro
  *   Talk 3: Catching up with the CryoEM Resolution Revolution

Speaker: Pedro Matias

Moderator: Maria Arménia Carrondo, Universidade Nova de Lisboa



You can view the full abstracts and register on the Instruct-ERIC 
website, where you can also watch 
recordings of the previous webinars.



Questions can be submitted in advance of the webinar by sending them to 
j...@instruct-eric.org.



We hope that you can join the webinar - please feel free to share this message 
with anyone who might be interested in attending.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Register now for Instruct-ERIC ‘Structure Meets Function’ webinar – 16 Nov

[ccp4mail]

Dear all,

Featuring expert speakers from Instruct Centres across Europe, the 
Instruct-ERIC webinar series, Structure Meets 
Function,
 highlights some of the latest developments in structural biology, 
demonstrating how integrative methods are enabling scientists to decipher the 
mechanisms that underpin health and disease.



Register 
now



[cid:c9303c7f-c080-410f-8723-1dd6d4b4472d]



Registration
 is open for the 14th webinar in the series, which will be hosted by Instruct 
Lithuania on 16 November 2021, 11:00 - 12:30 CET. The upcoming webinar will 
feature talks on the application of structural biology methods to better 
understand key aspects of protein complexes structure and function. The webinar 
speakers will discuss about the use of tethered phospholipid bilayer membranes 
to study protein membrane interactions and present work on the structural and 
molecular mechanisms of antiviral defense systems in bacteria and their use as 
molecular tools for targeted genome manipulation.



Talk 1: Biomembranes on a chip: tethered phospholipid bilayers for protein 
membrane interaction studies
Speaker: Dr Gintaras Valinčius



Talk 2: Bacterial immunity: from restriction enzymes to CRISPR
Speaker: Dr Virginijus Šikšnys



Moderator: Mindaugas Linkaitis, Vilnius University Life Sciences Center



You can view the full abstracts and register 

 on the Instruct-ERIC website, where you can also watch recordings of the 
previous 
webinars.



Questions can be submitted in advance of the webinar by sending them to 
paul...@instruct-eric.org.



We hope that you can join the webinar - please feel free to share this message 
with anyone who might be interested in attending.



Best wishes,

Instruct-ERIC Hub Team 




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/