[ccp4bb] 2-year postdoctoral position

[Omid Haji-Ghassemi]

Dear 3dEM list,

A position is available for a highly motivated and skilled Post-doctoral Fellow 
(PDF) at the University of Calgary in Calgary, Alberta, Canada. The successful 
candidate will lead X-ray and potentially cryo-EM experiments to understand 
receptor complex biology and drug targeting. The position will be held within 
the Departments of Biological Sciences under the co-supervision of Dr. Matt 
(Mathilakth) Vijayan and Dr. Omid Haji-Ghassemi. 
 
The successful applicant must have a Ph.D. in structural biology or related 
fields. Excellent theoretical knowledge and practical skills in either X-ray 
crystallography or other protein biophysical methods are required. This 
includes familiarity with the expression and purification of proteins.  The 
position forms part of a collaborative, multidisciplinary effort between the 
Vijayan and Haji-Ghassemi laboratories. As such, excellent oral and written 
English communication skills, the proven ability to work and as part of a team, 
and strong individual research productivity are essential.
 
Calgary is one of the sunniest and cleanest cities in North America. and has 
been named as one of the world’s most livable cities. Hence it is a great place 
to do research and build a career while living in an affordable city. Calgary 
is about an hour drive from the majestic Rocky Mountains and Banff.  

Qualified Applicants should submit a cover letter including contact information 
for three professional references, and a curriculum vitae including a list of 
publications. Application materials should be combined into a single PDF 
document and submitted via email to omid.hajighass...@calgary.ca. 

The position is available immediately. The appointment will be at the rank of 
Postdoctoral Fellow with an annual salary of 50,000, plus benefits for two 
years, with a possible 1-year extension. Candidates are encouraged to apply for 
post-doctoral fellowships including  Eyes High program from UCalgary. 

Equity and diversity are essential to academic excellence. An open and diverse 
community fosters the inclusion of voices that have been underrepresented or 
discouraged. We encourage applications from members of groups that have been 
marginalized on any the basis of sex, sexual orientation, gender identity or 
expression, racialization, disability, political belief, religion, marital or 
family status, age, and/or status as a First Nation, Metis, Inuit, or 
Indigenous person.



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[ccp4bb] 2-year postdoctoral position available - Structural Microbiology, Institut Pasteur

[Marco BELLINZONI]

Dear all,
A 2-year post-doc position is currently available at the Structural 
Microbiology Unit, located at the Institut Pasteur in Paris.
Our team has been working on the molecular mechanisms underlying the metabolic 
plasticity of Actinobacteria, with a special emphasis on the signaling pathways 
involved (for an overview of the topic and our recent work, please see Wagner 
et al., Sci. Signal., 2019; Bellinzoni et al., Genes Immun., 2019). The 
postdoctoral fellow will join an active and multidisciplinary environment, 
working on Corynebacterium glutamicum enzymes and protein complexes involved in 
central metabolism, and applying an integrative structural biology approach in 
which cryo-EM plays a key role. The project is part of a French-German 
initiative funded by the respective national research agencies (ANR and DFG), 
and will be performed in collaboration with the groups led by Profs. Michael 
Bott (Forschungszentrum Jülich) and Bernhard Eikmanns (University of Ulm).
The Structural Microbiology Unit is fully equipped for microbiology and protein 
biochemistry work, and has a well-established network of collaborations. In 
addition, the institute’s campus provides a vibrant scientific life as well as 
access to excellent core facilities. A full range of state-of-the-art equipment 
for structural biology and biophysics is available, including a Titan Krios and 
two Glacios microscopes currently undergoing installation. The unit has also 
regular access to synchrotron beamlines for X-ray crystallography and SAXS.
The position is open from October 2019, although the starting date may be 
arranged. The ideal candidate is an enthusiastic PhD with a good publication 
record and a solid background in protein biochemistry and biophysics. Good team 
spirit and presentation skills in English are essential; experience in dealing 
with large macromolecular complexes, protein-protein interaction studies and/or 
cryo-EM would be an asset. Interested candidates should provide a full CV with 
a summary of previous research experience, a brief statement of interest on the 
position and contacts of a couple of referees to marco (dot) bellinzoni (at) 
pasteur (dot) fr. Please send applications or informal enquiries no later than 
June 5.
Best regards,
Marco

===
Marco Bellinzoni
Unité de Microbiologie Structurale
Institut Pasteur
25, rue du Dr. Roux
75724 Paris Cedex 15
France
Tel: +33 (0)1 45688608
Fax: +33 (0)1 45688604
===






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[ccp4bb] 2-year Postdoctoral Position available at The Institute of Cancer Research, London UK

[Rob Van Montfort]

The Institute of Cancer Research, London, is one of the world’s most 
influential cancer research institutes, with an outstanding record of 
achievement dating back more than 100 years. We provided the first convincing 
evidence that DNA damage is the basic cause of cancer, laying the foundation 
for the now universally accepted idea that cancer is a genetic disease. Today, 
The Institute of Cancer Research (ICR) leads the world at isolating 
cancer-related genes and discovering new targeted drugs for personalised cancer 
treatment. Under the leadership of our Chief Executive, Professor Paul Workman 
FRS, the ICR is ranked as the UK’s leading academic research centre. Together 
with our partner The Royal Marsden, we are rated in the top four cancer centres 
globally. The ICR is committed to attracting, developing and retaining the best 
minds in the world to join us in our mission – to make the discoveries that 
defeat cancer.
The Cancer Research UK Cancer Therapeutics Unit (CTU), within the Division of 
Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, 
comprising around 160 staff dedicated to the discovery and development of novel 
therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s 
exciting goal is to discover high quality small molecule drug candidates and to 
progress these to clinical trial. All the scientific disciplines are in place 
to make this possible, including medicinal chemistry, biology, drug metabolism 
and clinical specialists who focus on new molecular targets emerging from human 
genome and ground breaking cell biology research.

A postdoctoral position is available in Dr Rob van Montfort’s Hit Discovery and 
Structural Design Team within the CTU. The Post-doc will be involved in 
high-throughput X-ray crystallography, fragment-based screening and 
structure-based drug design and will be responsible for protein expression, 
purification, crystallisation, structure determination and structural analysis 
of protein-ligand complexes from one of the CTU’s drug discovery programmes. 
The successful candidate will also be part of the Division of Structural 
Biology, in which the crystallographers in Dr van Montfort’s team are embedded, 
and will have access to state of the art crystallisation facilities, in-house 
X-ray sources and excellent access to synchrotrons. The successful candidate 
will interact closely with the biology, computational chemistry and medicinal 
chemistry teams at the CTU, and will therefore be expected to work across the 
two sites in Chelsea, London and Sutton, Surrey.

Applicants must have a PhD in a biological or physical science, and experience 
in macromolecular crystallography (to include protein biochemistry, protein 
crystallisation, & protein crystallography). Experience in molecular biology, 
protein expression in insect cells, structure-based drug design, and/or 
biophysics will be an advantage.



The starting salary will be in the range £29,960 to £36,830 p.a. inclusive 
(based on previous post-doctoral experience) and the post is offered on a fixed 
term contract of 2 years. Informal enquiries to 
rob.vanmontf...@icr.ac.uk or 
yann-vai.lebi...@icr.ac.uk. Closing date is 
July 9th 2017.

Please DO NOT send your application to Dr van Montfort or Dr Le Bihan; CVs must 
be submitted in line with the instructions below.

Dr. Rob van Montfort
Team Leader Hit Discovery and Structural Design
Joint Interim Head of Division of Structural Biology
Divisions of Cancer Therapeutics and Structural Biology
The Institute of Cancer Research
15 Cotswold Road
Sutton SM2 5NG
UK

Tel:
+44-(0)20-8722-4364 (Sutton)
+44-(0)20-7153-5142 (Chelsea)
Email: rob.vanmontf...@icr.ac.uk







The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company 
Limited by Guarantee, Registered in England under Company No. 534147 with its 
Registered Office at 123 Old Brompton Road, London SW7 3RP.

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