[ccp4bb] PhD position in Germany

[Wolf, Eva]

Dear all,

Please find below the advertisement for a PhD position in our research group:

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PhD position in Structural Biology at JGU/IMB Mainz, Germany
A PhD position is available in the group of Eva Wolf at the Johannes Gutenberg 
University
(JGU) and the Institute of Molecular Biology (IMB) in Mainz, Germany. Research 
in the Wolf
group is focused on the structural, biochemical and biophysical analysis of 
proteins involved
in circadian (day-time dependent) regulation (e.g. Czarna et al, Cell 2013; 
Schmalen et al,
Cell 2014) and in genome maintenance (e.g. Witosch et al, NAR 2014).
To elucidate the molecular mechanisms underlying circadian gene regulation and 
circadian
physiology, the PhD student will apply a wide range of techniques including 
3D-structural
analyses (e.g. X-ray crystallography, Cryo-EM, SAXS, Crosslink-MS), biochemical 
and
biophysical protein interaction studies as well as UV/VIS spectroscopy. To 
produce highly
pure proteins and protein complexes for these applications, she/he will perform 
cloning,
recombinant protein expression (E.coli, insect cells) and protein purification 
using FPLC
systems. Within collaborations, she/he will also analyze clock protein 
interactions and protein
functions in cell-based approaches and in in vivo systems. Candidates with a 
strong interest
in structural biology and protein biochemistry combined with a significant 
previous exposure
to these research areas during their master education are encouraged to apply.
The prospective PhD student will be affiliated with IMB’s International PhD 
program (IPP)
and must have a good command of English. PhD candidates must officially apply 
via the
International PhD Programme (IPP, 
www.imb-mainz.de/students-postdocs/international-phd-programme).
 The deadline for registration at the IPP is May 26th 2020. Informal inquiries 
should be addressed
to Eva Wolf (evawo...@uni-mainz.de).

With best regards,

Eva Wolf

---
Prof. Dr. Eva Wolf
Structural Chronobiology
IMB and University Mainz Ackermannweg 4 55128 Mainz, Germany
evawo...@uni-mainz.de
https://www.imb.de/research/wolf/research/



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[ccp4bb] PhD Position Munich (Germany)

[Messias, Ana, Dr.]

PhD Position in structure-based drug design in diabetes at the Institute of 
Structural Biology, Helmholtz Zentrum München, Munich (Germany)

Job Details
The need for new and more effective drugs for type 2 diabetes is a major health 
concern. The main objective of this project is to discover new selective 
compounds targeting proteins relevant in type 2 diabetes using structure-based 
approaches.

Qualifications
-   We are looking for a highly motivated candidate who has interest in 
protein expression, structural biology (NMR and X-ray crystallography), 
diabetes and drug design.
-   Applicants should have a Masters  in Biochemistry with an above-average 
grade, and practical experience in basic methods of molecular biology and 
protein biochemistry.
-   Previous experience in NMR, crystallography or drug design is a plus.
-   The candidate must be innovative, highly motivated, and with a strong 
interest in team work.
-   Strong communication and organizational skills are expected.

Inquiries should be addressed  to Dr. Ana Messias 
(ana.mess...@helmholtz-muenchen.de)

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Dr. Ana Messias
Helmholtz Zentrum München
Institute of Structural Biology
(Building 43b, room 103)
Ingolstädter Landstr. 1
85764 Neuherberg
Germany

Tel: +49 (0)89 3187- 4706 (office) / - 3732 (lab)
E-mail: ana.mess...@helmholtz-muenchen.de
---

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstr. 1
85764 Neuherberg
www.helmholtz-muenchen.de
Aufsichtsratsvorsitzende: MinDir´in Bärbel Brumme-Bothe
Geschäftsführer: Prof. Dr. Günther Wess und Dr. Nikolaus Blum
Registergericht: Amtsgericht München HRB 6466
USt-IdNr: DE 129521671