A Cancer Research UK-funded Postdoctoral Research Fellow position is immediately available in the laboratory of Professor Laurence Pearl FRS and Dr Antony Oliver, to study the structural basis for the assembly and specificity of multi-protein complexes involved in the recognition and repair of DNA damage, and DNA damage signalling.
The internationally renowned MRC Genome Damage and Stability Centre and the School of Life Sciences are very well equipped for all aspects of modern structural biology, with state-of-the-art laboratories for molecular biology, recombinant expression in bacterial and eukaryotic hosts, biochemistry, biophysics and X-ray crystallography. Excellent synchrotron access (~ 2 days/month) is also available through rolling beam-allocation programmes at both the Diamond Light Source and ESRF. Applicants must have a PhD, and extensive experience in recombinant expression and protein purification. Previous experience of crystallization and X-ray crystallography would be a distinct advantage. The post-holder will be responsible for expression, purification, crystallization and structure determination of protein-protein and protein-DNA complexes, plus downstream biochemical and biophysical characterisation. The Genome Damage and Stability Centre is an internationally renowned Institute carrying out research on the response of cells to DNA damage, genome instability and its relationship to human disease. We provide a stimulating and supportive environment and our expertise covers a range of experimental systems. Further information about our research can be obtained by visiting our website at: http://www.sussex.ac.uk/gdsc Fixed term for three years, full time. Salary range: starting at £30,424 and rising to £36,298 per annum, commensurate with level of experience. Closing date for applications: 17 May 2013 Expected start date: 1st June 2013 or as soon as possible thereafter. === Please note that previous applicants for Job Reference 768, advertised in August 2012, should not reapply. Full information and instructions for APPLICANTS can also be found at the following URL: http://www.sussex.ac.uk/aboutus/jobs/090 ==== WORD format Application Form: http://www.sussex.ac.uk/humanresources/documents/acadnw.doc PDF format Application Form: http://www.sussex.ac.uk/humanresources/documents/acadnw.pdf Application forms should be completed and sent via e-mail to: lifescirecruitm...@sussex.ac.uk When emailing your application please use the following format in the 'subject' line: (post reference number / post title / your name). If you are applying for more than one post advertised by the University, please send a separate email and application form for each post. Please attach your completed application form and any other documents directly to the email rather than using a web-based upload / weblink service (e.g. SkyDrive) otherwise we may not receive your application due to incompatibility with our email software. Alternatively, completed applications forms may be posted to: Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH. Applications should be received by midnight on the closing date. INFORMAL enquiries ONLY may be made to Professor Pearl: laurence.pe...@sussex.ac.uk, or Dr Oliver: antony.oli...@sussex.ac.uk ====
