An attractive post-doctoral position is available within the laboratory of Dr Mike Lawrence and Dr Colin Ward in the Structural Biology Division of the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, Australia. The position is available immediately and is for two years in the first instance. Experience in protein purification and protein crystallization is essential.

The project involves studying the structural biology of the interaction between the insulin-like growth factors and the ectodomain of the Type 1 insulin-like growth factor receptor. The project builds on the PIs’ earlier success in determining the structure of the insulin receptor ectodomain (for a review see Lawrence MC, McKern NM, Ward CW, Curr Opin Struct Biol. 2007, 17:699-705). For more information regarding the project please contact Dr Mike Lawrence (email lawre...@wehi.edu.au).

The Walter and Eliza Hall Institute of Medical Research is located in Parkville, just north of Melbourne's CBD and is one of the world's leading medical research centres. The work of the Institute covers cancer, genetics, malaria, autoimmune diseases, medicinal chemistry, drug discovery and translational research taking scientific discoveries from the laboratory to the clinic.

The Structural Biology Division is well equipped, housing in particular a Rigaku Micromax-007 X-ray generator, with two Raxis IV++ detectors, AXCO micro-capillary focussing optics and X-stream cryo- units. In addition, WEHI is a Partner in the Bio21 Collaborative Crystallization Centre, which houses state-of-the-art protein crystallization robotics. The newly-operational Australian Synchrotron is approximately 20 km from WEHI and has two PX beamlines. Access is guaranteed by means of WEHI's Foundation Investor status.

Please forward applications by email to jobapplicati...@wehi.edu.au. Cite the ccp4bb as the advertisement source and include a covering letter, curriculum vitae and contact details for three referees. The closing date is 26 February 2009.

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