INSTITUTE OF HUMAN VIROLOGY UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE A postdoctoral positions are available immediately for a highly motivated candidates in the Institute of Human Virology http://www.ihv.org at the University Of Maryland School Of Medicine (UMSOM; http://medschool.umaryland.edu ) in Baltimore, Maryland. IHV is the first center in the United States - perhaps the world - to combine the disciplines of basic science, epidemiology and clinical research in a concerted effort to speed the discovery of diagnostics and therapeutics for a wide variety of chronic and deadly viral and immune disorders - most notably HIV, the cause of AIDS. Our laboratory focuses on the molecular basis of function of proteins involved in the anti-HIV-1 immune responses, human immune defense in general, and cancer prevention (http://www.ihv.org/research/bio_recognition ). Successful candidate will utilize the established high-throughput structural biology platform and biochemical/biophysical techniques to study novel targets on HIV-1 Env that are exposed during viral attachement/entry and are exclusively responsible for Fc mediated effector function (ADCC). Studies will focus on structural characterization and epitope definition of ADCC-mediating anti-HIV-1 Env mAbs, as well as the structure-based studies guiding development of protein-based therapeutics and novel vaccines. The position requires a Ph.D. in biochemistry, molecular biology, or a closely related discipline with practical experience in molecular biology, antibody/glycoprotein engineering and protein science techniques including surface plasmon resonance, isothermal titration calorimetry and X-ray crystallography. Candidates need to be highly motivated individuals who enjoy working as part of a young, dynamic, collaborative and multidisciplinary team. Excellent oral and written communication skills are essential. Interested parties should submit electronically a CV, a statement of research interests and previous experience, and contact information of three references to mpazg...@ihv.umaryland.edu<mailto:mpazg...@ihv.umaryland.edu> Review of completed applications will begin immediately.
