PostdoctoralPositions in Engineering Ion channels and Transporters
          Two postdoctoral positions are availablein the Valiyaveetil group at 
Oregon Health and Science University in Portland,Oregon. The Valiyaveetil group 
investigates structure and function of ionchannels and transporters using a 
combination of unnatural amino acid mutagenesis,electrophysiology, structural 
biology and spectroscopy.  See references [Nat Commun, (2019), 9, 5055; PNAS 
(2019) 116,15939-15946] forexamples of recent research from the lab. The group 
is a part of the Program in Chemical Biology in the Departmentof Chemical 
Physiology and Biochemistry.

          The positions are suitable for highlymotivated candidates with a 
recent (less than 1 year) Ph.D. in Biochemistry, Biophysicsor a related 
discipline.  The first candidatewill investigate ion channels using unnatural 
amino acid mutagenesis, functionaland structural studies.  Candidates forthis 
position should have prior research experience in ion channels and have 
expertisein carrying out electrophysiological measurements using two-electrode 
voltage clampor patch clamp.  The second candidatewill investigate transporters 
using a combination of biochemical, spectroscopicand structural approaches.  
Candidatesfor this position should have prior experience in membrane protein 
biochemistryand prior expertise in structural approaches such as 
crystallography or cryo-EMor in fluorescence or EPR spectroscopy will be a 
plus.  These positions provides the candidates witha unique opportunity to 
enhance their skill set with the techniques for membraneprotein engineering 
using unnatural amino acid mutagenesis.  

          The Valiyaveetil lab is well equippedto carry out structural and 
functional studies of ion channels and transporters.  OHSU provides an 
excellent scientificenvironment.  Portland is consistentlyrated as one of the 
most livable cities in the US.  

          To apply send CV, a 1-2 pagedescription of graduate research and 
future research plans along with contactinformation for three references by 
email to: valiy...@ohsu.edu  



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