I have seen such features myself from time to time on diffraction pictures 
recorded on X-ray films in the far past and was explaining them by the presence 
of electron diffraction as they resemble electron diffraction patterns.
Source of focused electron beam during X-ray diffraction experiment is a 
different story. I have no explanation for that. BTW1 when we started to use 
area detectors, these features disappeared.
However features David Goldstone showing us is something else. "We never have 
seen such things before".
I would try to take a similar picture on X-ray film. But maybe "why to 
bother?". Unfortunately to be a genius of X-ray diffraction physics in the 
present MX world will fast convert a person to homeless.  
My question to John Goldstone: Is it intermittent, of for certain 
crystal/station/detector you always get that?
BTW2 I feel in contemptuous reaction of the community deep discontent of all of 
us.....What? even diffraction physics we do not understand in depth?   

Dr Felix Frolow   Professor of Structural Biology and Biotechnology
Department of Molecular Microbiology
and Biotechnology 
Tel Aviv University 69978, Israel

Acta Crystallographica F, co-editor

e-mail: mbfro...@post.tau.ac.il
Tel:  ++972-3640-8723
Fax: ++972-3640-9407
Cellular: 0547 459 608

On Oct 29, 2010, at 23:23 , Charles W. Carter, Jr wrote:

> Hi GĂ©rard, 
> 
> I actually bought John's book some time ago and can provide page 321 
> (attached). I think perhaps John is exaggerating his case, although as I have 
> frequently made similarly inflated claims, I am sympathetic. 
> 
> Here is the pdf file. If it does not go through the CCP4 filters, I would be 
> happy to send it to the first few who request it.
> 
> Charlie
> 
> <p321.PDF>
> On Oct 29, 2010, at 11:03 PM, Gerard Bricogne wrote:
> 
>> Dear Liz,
>> 
>>    You will be disappointed. I went immediately to that link, but page 321
>> is not available as part of the Googlebook sample, which jumps directly from
>> page 320 to page 325. 
>> 
>> 
>>    With best wishes,
>> 
>>         Gerard.
>> 
>> --
>> On Fri, Oct 29, 2010 at 09:13:27PM +0100, elizabeth.d...@diamond.ac.uk wrote:
>>> There is always hope!!!
>>> 
>>> Seriously though, I have never seen anything like this before! I am 
>>> watching this thread with interest to see what others suggest.
>>> 
>>> THanks Also thanks should go specifically to Julian Nomme who took the 
>>> trouble to send us all the Helliwell book  link. 
>>> 
>>> Liz
>>> 
>>> ________________________________
>>> 
>>> From: CCP4 bulletin board on behalf of Sanishvili, Ruslan
>>> Sent: Fri 29/10/2010 21:08
>>> To: CCP4BB@JISCMAIL.AC.UK
>>> Subject: Re: [ccp4bb] Strange spots
>>> 
>>> 
>>> 
>>> C'mon now! Everybody knows that frogs in real space become handsome princes 
>>> in the reciprocal one...
>>> 
>>> N.
>>> 
>>> 
>>> 
>>> Ruslan Sanishvili (Nukri), Ph.D.
>>> 
>>> GM/CA-CAT
>>> Biosciences Division, ANL
>>> 9700 S. Cass Ave.
>>> Argonne, IL 60439
>>> 
>>> Tel: (630)252-0665
>>> Fax: (630)252-0667
>>> rsanishv...@anl.gov 
>>> 
>>> ________________________________
>>> 
>>> From: CCP4 bulletin board [mailto:ccp...@jiscmail.ac.uk] On Behalf Of Jacob 
>>> Keller
>>> Sent: Friday, October 29, 2010 3:00 PM
>>> To: CCP4BB@JISCMAIL.AC.UK
>>> Subject: Re: [ccp4bb] Strange spots
>>> 
>>> 
>>> 
>>> 
>>> 
>>> Yes, but the question is what in real space gives rise to reciprocal-space 
>>> frog spawn? (Frogs, I guess?)
>>> 
>>>      
>>> 
>>>     ----- Original Message ----- 
>>> 
>>>     From: Marcus Winter <mailto:marcus.win...@agilent.com>  
>>> 
>>>     To: CCP4BB@JISCMAIL.AC.UK 
>>> 
>>>     Sent: Friday, October 29, 2010 2:56 PM
>>> 
>>>     Subject: Re: [ccp4bb] Strange spots
>>> 
>>>      
>>> 
>>>      
>>> 
>>>      
>>> 
>>>      
>>> 
>>>     Dear David, 
>>> 
>>>      
>>> 
>>>      
>>> 
>>>     Further to the previous learned responses, surely, this 
>>> 
>>>     is just frog spawn ?
>>> 
>>>      
>>> 
>>>     My apologies: it is a Friday evening, after all...
>>> 
>>>      
>>> 
>>>      
>>> 
>>>     Marcus Winter.
>>> 
>>>      
>>> 
>>>      
>>> 
>>>      
>>> 
>>>     -----Original Message-----
>>>     From: CCP4 bulletin board [mailto:ccp...@jiscmail.ac.uk] On Behalf Of 
>>> David Goldstone
>>>     Sent: 29 October 2010 17:08
>>>     To: CCP4BB@JISCMAIL.AC.UK
>>>     Subject: [ccp4bb] Strange spots
>>> 
>>>      
>>> 
>>>     Dear All,
>>> 
>>>      
>>> 
>>>     Does anyone have any insight into what the circles around the spots 
>>> might be?
>>> 
>>>      
>>> 
>>>     cheers
>>> 
>>>      
>>> 
>>>     Dave
>>> 
>>>     --
>>> 
>>>     David Goldstone, PhD
>>> 
>>>     National Institute for Medical Research
>>> 
>>>     Molecular Structure
>>> 
>>>     The Ridgeway
>>> 
>>>     Mill Hill
>>> 
>>>     London NW7 1AA
>>> 
>>>      
>>> 
>>> 
>>> 
>>> 
>>> 
>>> *******************************************
>>> Jacob Pearson Keller
>>> Northwestern University
>>> Medical Scientist Training Program
>>> Dallos Laboratory
>>> F. Searle 1-240
>>> 2240 Campus Drive
>>> Evanston IL 60208
>>> lab: 847.491.2438
>>> cel: 773.608.9185
>>> email: j-kell...@northwestern.edu
>>> *******************************************
> 

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