Re: [ccp4bb] post-doc position at KU Leuven, ligand-gated ion channels

[Chris Ulens]

A post-doctoral position is available at the Laboratory of Prof. Chris Ulens, 
KU Leuven, Belgium (http://www.xtal.be ). The research in 
the Laboratory of Structural Neurobiology is aimed at understanding the 
molecular mechanism of ligand-gated ion channels. Our methods rely on X-ray 
crystallography and cryo-EM in combination with electrophysiological recordings 
and fluorescence-based techniques. Our laboratory hosts an integrated 
macromolecular crystallization facility with a Mosquito crystallization robot 
and two RockImagers. We have access to a 200 kV Glacios microscope on campus as 
well as 300 kV JEOL CryoARM300 at the nearby EM facility in Brussels. Current 
projects are situated at the crossroads of structural elucidation and drug 
discovery of different pentameric ligand-gated ion channels.

We would like to recruit a post-doc with prior experience in cryo-EM or X-ray 
crystallography of membrane proteins. The position is open immediately and 
applications will be accepted until the position is filled. Applicants are 
requested to submit a CV with publication list and two references. E-mail to 
chris.ul...@kuleuven.be 


Selection of recent publications:


A lipid site shapes the agonist response of a pentameric ligand-gated ion 
channel. Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, Lynch 
J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, Brannigan 
G, Nury H, Steyaert J, Baenziger JE, Ulens C. Nat Chem Biol. 
2019;15(12):1156-1164. doi: 10.1038/s41589-019-0369-4.


Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 
receptor via a common vestibule site. Brams M, Govaerts C, Kambara K, Price KL, 
Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs RE, 
Steyaert J, Ulens C. Elife. 2020;9:e51511. doi: 10.7554/eLife.51511.


The structural basis for an on-off switch controlling Gβγ-mediated inhibition 
of TRPM3 channels. Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous 
PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, 
Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Proc 
Natl Acad Sci U S A. 2020;117(46):29090-29100. doi: 10.1073/pnas.2001177117.


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[ccp4bb] post-doc position at KU Leuven, ligand-gated ion channels

[Chris Ulens]

A post-doctoral position is available at the Laboratory of Prof. Chris Ulens, 
KU Leuven, Belgium (http://www.xtal.be ). The research in 
the Laboratory of Structural Neurobiology is aimed at understanding the 
molecular mechanism of ligand-gated ion channels. Our methods rely on X-ray 
crystallography and cryo-EM in combination with electrophysiological recordings 
and fluorescence-based techniques. Our laboratory hosts an integrated 
macromolecular crystallization facility with a Mosquito crystallization robot 
and two RockImagers. We have access to a 200 kV Glacios microscope on campus as 
well as 300 kV JEOL CryoARM300 at the nearby EM facility in Brussels. Current 
projects are situated at the crossroads of structural elucidation and drug 
discovery of different pentameric ligand-gated ion channels.

We would like to recruit a post-doc with prior experience in cryo-EM or X-ray 
crystallography of membrane proteins.

The successful candidate:

- easily communicates in an open verbal manner and has a team player spirit
- has an ambitious work ethic
- critically contributes to writing of manuscripts and grant proposals
- makes efforts to obtain independent funding
- meets intermediate deadlines and brings projects to a successful end
- fuels internal discussions of recent publications in the field
- sets an example to younger PhD students in the lab
- identifies directions for future scientific research


The position is open immediately and applications will be accepted until the 
position is filled. Applicants are requested to submit a CV with publication 
list and two references. E-mail to chris.ul...@kuleuven.be 



Selection of recent publications:


A lipid site shapes the agonist response of a pentameric ligand-gated ion 
channel. Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, Lynch 
J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, Brannigan 
G, Nury H, Steyaert J, Baenziger JE, Ulens C. Nat Chem Biol. 
2019;15(12):1156-1164. doi: 10.1038/s41589-019-0369-4.


Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 
receptor via a common vestibule site. Brams M, Govaerts C, Kambara K, Price KL, 
Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs RE, 
Steyaert J, Ulens C. Elife. 2020;9:e51511. doi: 10.7554/eLife.51511.


The structural basis for an on-off switch controlling Gβγ-mediated inhibition 
of TRPM3 channels. Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous 
PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, 
Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Proc 
Natl Acad Sci U S A. 2020;117(46):29090-29100. doi: 10.1073/pnas.2001177117.


To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

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[ccp4bb] post-doc position at KU Leuven, ligand-gated ion channels

[Chris Ulens]

A post-doctoral position is available at the Laboratory of Prof. Chris Ulens, 
KU Leuven, Belgium (http://www.xtal.be ). The research in 
the Laboratory of Structural Neurobiology is aimed at understanding the 
molecular mechanism of ligand-gated ion channels. Our methods rely on X-ray 
crystallography and cryo-EM in combination with electrophysiological recordings 
and fluorescence-based techniques. Our laboratory hosts an integrated 
macromolecular crystallization facility with a Mosquito crystallization robot 
and two RockImagers. We have access to a 200 kV Glacios microscope on campus as 
well as 300 kV JEOL CryoARM300 at the nearby EM facility in Brussels. Current 
projects are situated at the crossroads of structural elucidation and drug 
discovery of different pentameric ligand-gated ion channels.

We would like to recruit a post-doc with prior experience in cryo-EM or X-ray 
crystallography of membrane proteins.

The successful candidate:

- easily communicates in an open verbal manner and has a team player spirit
- has an ambitious work ethic
- critically contributes to writing of manuscripts and grant proposals
- makes efforts to obtain independent funding
- meets intermediate deadlines and brings projects to a successful end
- fuels internal discussions of recent publications in the field
- sets an example to younger PhD students in the lab
- identifies directions for future scientific research


The position is open immediately and applications will be accepted until the 
position is filled. Applicants are requested to submit a CV with publication 
list and two references. E-mail to chris.ul...@kuleuven.be 



Selection of recent publications:


A lipid site shapes the agonist response of a pentameric ligand-gated ion 
channel. Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, Lynch 
J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, Brannigan 
G, Nury H, Steyaert J, Baenziger JE, Ulens C. Nat Chem Biol. 
2019;15(12):1156-1164. doi: 10.1038/s41589-019-0369-4.


Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 
receptor via a common vestibule site. Brams M, Govaerts C, Kambara K, Price KL, 
Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs RE, 
Steyaert J, Ulens C. Elife. 2020;9:e51511. doi: 10.7554/eLife.51511.


The structural basis for an on-off switch controlling Gβγ-mediated inhibition 
of TRPM3 channels. Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous 
PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, 
Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Proc 
Natl Acad Sci U S A. 2020;117(46):29090-29100. doi: 10.1073/pnas.2001177117.


To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

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hosted by www.jiscmail.ac.uk, terms & conditions are available at 
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Re: [ccp4bb] post-doc position at KU Leuven, ligand-gated ion channels

[Chris Ulens]

A post-doctoral position is available at the Laboratory of Prof. Chris Ulens, 
KU Leuven, Belgium (http://www.xtal.be). The research in the Laboratory of 
Structural Neurobiology is aimed at understanding the molecular mechanism of 
ligand-gated ion channels. Our methods rely on X-ray crystallography and 
cryo-EM in combination with electrophysiological recordings and 
fluorescence-based techniques. Our laboratory hosts an integrated 
macromolecular crystallization facility with a Mosquito crystallization robot 
and two RockImagers. We have access to a 200 kV Glacios microscope on campus as 
well as 300 kV JEOL CryoARM300 at the nearby EM facility in Brussels. Current 
projects are situated at the crossroads of structural elucidation and drug 
discovery of different pentameric ligand-gated ion channels.

 We would like to recruit a post-doc with prior experience in cryo-EM or X-ray 
crystallography of membrane proteins.
 
The successful candidate:

- easily communicates in an open verbal manner and has a team player spirit
- has an ambitious work ethic
- critically contributes to writing of manuscripts and grant proposals
- makes efforts to obtain independent funding
- meets intermediate deadlines and brings projects to a successful end
- fuels internal discussions of recent publications in the field
- sets an example to younger PhD students in the lab
- identifies directions for future scientific research

 
The position is open immediately and applications will be accepted until the 
position is filled. Applicants are requested to submit a CV with publication 
list and two references. E-mail to chris.ul...@kuleuven.be

 
Selection of recent publications:

 
A lipid site shapes the agonist response of a pentameric ligand-gated ion 
channel. Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, Lynch 
J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, Brannigan 
G, Nury H, Steyaert J, Baenziger JE, Ulens C. Nat Chem Biol. 
2019;15(12):1156-1164. doi: 10.1038/s41589-019-0369-4.

 
Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 
receptor via a common vestibule site. Brams M, Govaerts C, Kambara K, Price KL, 
Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs RE, 
Steyaert J, Ulens C. Elife. 2020;9:e51511. doi: 10.7554/eLife.51511.

 
The structural basis for an on-off switch controlling Gβγ-mediated inhibition 
of TRPM3 channels. Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous 
PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, 
Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Proc 
Natl Acad Sci U S A. 2020;117(46):29090-29100. doi: 10.1073/pnas.2001177117.


To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
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Re: [ccp4bb] post-doc position at KU Leuven, ligand-gated ion channels

[Chris Ulens]

This is a reminder for interested candidates to apply for the vacant position 
below.

Thank you and best regards
Chris


> On 5 Jan 2021, at 17:33, Chris Ulens  wrote:
> 
> A post-doctoral position is available at the Laboratory of Prof. Chris Ulens, 
> KU Leuven, Belgium (http://www.xtal.be ). The research 
> in the Laboratory of Structural Neurobiology is aimed at understanding the 
> molecular mechanism of ligand-gated ion channels. Our methods rely on X-ray 
> crystallography and cryo-EM in combination with electrophysiological 
> recordings and fluorescence-based techniques. Our laboratory hosts an 
> integrated macromolecular crystallization facility with a Mosquito 
> crystallization robot and two RockImagers. We have access to a 200 kV Glacios 
> microscope on campus as well as 300 kV JEOL CryoARM300 at the nearby EM 
> facility in Brussels. Current projects are situated at the crossroads of 
> structural elucidation and drug discovery of different pentameric 
> ligand-gated ion channels.
> 
>  
> We would like to recruit a post-doc with prior experience in cryo-EM or X-ray 
> crystallography of membrane proteins.
> 
>  
> The successful candidate:
> 
> - easily communicates in an open verbal manner and has a team player spirit
> 
> - has an ambitious work ethic
> 
> - critically contributes to writing of manuscripts and grant proposals
> 
> - makes efforts to obtain independent funding
> 
> - meets intermediate deadlines and brings projects to a successful end
> 
> - fuels internal discussions of recent publications in the field
> 
> - sets an example to younger PhD students in the lab
> 
> - identifies directions for future scientific research
> 
>  
> The position is open immediately and applications will be accepted until the 
> position is filled. Applicants are requested to submit a CV with publication 
> list and two references. E-mail to chris.ul...@kuleuven.be 
> 
>  
> Selection of recent publications:
> 
>  
> A lipid site shapes the agonist response of a pentameric ligand-gated ion 
> channel. Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, 
> Lynch J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, 
> Brannigan G, Nury H, Steyaert J, Baenziger JE, Ulens C. Nat Chem Biol. 
> 2019;15(12):1156-1164. doi: 10.1038/s41589-019-0369-4.
> 
>  
> Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 
> receptor via a common vestibule site. Brams M, Govaerts C, Kambara K, Price 
> KL, Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs 
> RE, Steyaert J, Ulens C. Elife. 2020;9:e51511. doi: 10.7554/eLife.51511.
> 
>  
> The structural basis for an on-off switch controlling Gβγ-mediated inhibition 
> of TRPM3 channels. Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, 
> Crassous PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, 
> Economou A, Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, 
> Oberwinkler J. Proc Natl Acad Sci U S A. 2020;117(46):29090-29100. doi: 
> 10.1073/pnas.2001177117.
> 
> 
> To unsubscribe from the CCP4BB list, click the following link:
> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 
> 



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Description: S/MIME cryptographic signature

[ccp4bb] post-doc position at KU Leuven, ligand-gated ion channels

[Chris Ulens]

A post-doctoral position is available at the Laboratory of Prof. Chris Ulens, 
KU Leuven, Belgium (http://www.xtal.be ). The research in 
the Laboratory of Structural Neurobiology is aimed at understanding the 
molecular mechanism of ligand-gated ion channels. Our methods rely on X-ray 
crystallography and cryo-EM in combination with electrophysiological recordings 
and fluorescence-based techniques. Our laboratory hosts an integrated 
macromolecular crystallization facility with a Mosquito crystallization robot 
and two RockImagers. We have access to a 200 kV Glacios microscope on campus as 
well as 300 kV JEOL CryoARM300 at the nearby EM facility in Brussels. Current 
projects are situated at the crossroads of structural elucidation and drug 
discovery of different pentameric ligand-gated ion channels.

 

We would like to recruit a post-doc with prior experience in cryo-EM or X-ray 
crystallography of membrane proteins.

 

The successful candidate:

- easily communicates in an open verbal manner and has a team player spirit

- has an ambitious work ethic

- critically contributes to writing of manuscripts and grant proposals

- makes efforts to obtain independent funding

- meets intermediate deadlines and brings projects to a successful end

- fuels internal discussions of recent publications in the field

- sets an example to younger PhD students in the lab

- identifies directions for future scientific research

 

The position is open immediately and applications will be accepted until the 
position is filled. Applicants are requested to submit a CV with publication 
list and two references. E-mail to chris.ul...@kuleuven.be 

 

Selection of recent publications:

 

A lipid site shapes the agonist response of a pentameric ligand-gated ion 
channel. Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, Lynch 
J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, Brannigan 
G, Nury H, Steyaert J, Baenziger JE, Ulens C. Nat Chem Biol. 
2019;15(12):1156-1164. doi: 10.1038/s41589-019-0369-4.

 

Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 
receptor via a common vestibule site. Brams M, Govaerts C, Kambara K, Price KL, 
Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs RE, 
Steyaert J, Ulens C. Elife. 2020;9:e51511. doi: 10.7554/eLife.51511.

 

The structural basis for an on-off switch controlling Gβγ-mediated inhibition 
of TRPM3 channels. Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous 
PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, 
Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Proc 
Natl Acad Sci U S A. 2020;117(46):29090-29100. doi: 10.1073/pnas.2001177117.


To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
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