Package: wnpp Severity: wishlist Subject: ITP: tandem-genotypes -- compare lengths of duplications in DNA sequences Package: wnpp Owner: Steffen Moeller <moel...@debian.org> Severity: wishlist
* Package name : tandem-genotypes Version : 1.8.2 Upstream Author : Martin C. Frith <mcfr...@gmail.com> * URL : https://github.com/mcfrith/tandem-genotypes * License : GPL-3.0 Programming Lang: Python Description : compare lengths of duplications in DNA sequences Only a fraction of the DNA in the human genome (and that of other species that are not optimised for the speed of their replication like viruses) are coding for genes. Other parts may be binding to transcription factors or direct the expression of genes in other ways - these other bits may not be fully understood, and parts may indeed be "junk", but this is only until we find a clinical feature to be statistically associated with something statistically noteworthy in the DNA sequences. . Features that somehow seem informative when looking at the DNA are whatever does not look like random. This tool looks at a special case of repeats - short regions that are duplicated, i.e. they appear as a tandem. When these repeats are longer, then these would be referred as microsatellites. . When interested in structural variations, within a family/population or to compare cancer tissue with benign samples, you may also want to look at these repeats. This software determines the lengths (and changes to the lenghts) across samples and knows how to present this graphically. Remark: This package is maintained by Steffen Moeller at https://salsa.debian.org/med-team/tandem-genotypes