Re: [ECOLOG-L] dna from museum skins and pickled animals

2008-12-25 Thread Anon 

malcolm McCallum wrote:

Hi,
how much of the genome can be obtained from museum skins and other
kinds of preserved specimens?
Can we get complete genomes or only fractions?

I do realize a lot of factors play into this!

I'm not an expert, but I would have thought we could get a full genome. 
 The sequencing methods that are being used now rely on quickly 
sequencing lots of short segments, and then fitting them together 
afterwards.  The problem with museum specimens, of course, is that the 
DNA is degraded, and in small segments already.


This is how they could sequence the Neanderthal genome (um, Neanderthal 
man, not the valley...).


Bob

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[ECOLOG-L] dna from museum skins and pickled animals

2008-12-24 Thread malcolm McCallum 
Hi,
how much of the genome can be obtained from museum skins and other
kinds of preserved specimens?
Can we get complete genomes or only fractions?

I do realize a lot of factors play into this!

-- 
Malcolm L. McCallum
Associate Professor of Biology
Texas A&M University-Texarkana
Editor, Herpetological Conservation and Biology
http://www.herpconbio.org

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