Re: [Felvtalk] Chablis - seeking advise about giving Pred/Doxy/Winstrol with low WBC

2019-07-26 Thread Deborah Whorley
Amani - have you ever received any feedback from others who have tried your
protocol and what their results were? Repeating labs this morning and will
present your protocol and history to see if she will let us try.

Thanks,
Deb

On Thu, Jul 25, 2019 at 10:45  wrote:

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>1. Re: Chablis - seeking advise about giving Pred/Doxy/Winstrol
>   with low WBC (Amani Oakley)
>
>
> --
>
> Message: 1
> Date: Thu, 25 Jul 2019 16:45:12 +
> From: Amani Oakley 
> To: "felvtalk@felineleukemia.org" 
> Subject: Re: [Felvtalk] Chablis - seeking advise about giving
> Pred/Doxy/Winstrol with low WBC
> Message-ID:
>  >
> Content-Type: text/plain; charset="utf-8"
>
> Hi Deborah
>
> The CBC results are unusual. There is some anemia going on, and there is
> the low white cell count. There is also an elevated monocyte count.
>
> Most people are aware that white cells go up with an infection, but they
> can also go quite low with an infection ? often if there is a focal area of
> inflammation/infection and white cells are moving out of the circulatory
> system to go to the site of infection in the tissues. My worry is that
> there ma be a source of infection somewhere. Monocytes can be elevated with
> a chronic infection as well.
>
> If it were my cat, I think I might ask the vets to give more in the way of
> antibiotics, with a broad enough spectrum to cover Gram positive and Gram
> negative organisms. I think I might insist on using Doxycycline along with
> another antibiotic, because the Doxycycline also has an effect on some more
> unusual organisms like some parasites and some viruses even. I think I
> would also try the Winstrol if it were me. Winstrol has an excellent
> enhancing effect on appetite, and may also help with the anemia. I myself
> wouldn?t be that worried about the prednisone/prednisolone but it probably
> wouldn?t hurt to hold off on that one and see if you get some improvement
> on the Doxycycline/Other Antibiotic/Winstrol combination.
>
> Amani
>
> From: Felvtalk  On Behalf Of Deborah
> Whorley
> Sent: July 25, 2019 2:59 AM
> To: felvtalk@felineleukemia.org
> Subject: [Felvtalk] Chablis - seeking advise about giving
> Pred/Doxy/Winstrol with low WBC
>
> Hi - one of my FeLV+ cats, Chablis (F, 5 yrs), has been dealing with
> constipation since Jan of this year. Last week she stopped eating like she
> does when she is ?backed up? but 100 cc SQ fluids didn?t resolve the issue
> as it normally does. She also started wheezing Sat eve.  I ended up with
> her in the emergency clinic on Sun and to my surprise her CBC was terrible
> (see below). Radiograph revealed no constipation or obvious masses in
> lungs/abdomen. ER vet, and my vet the next day, reluctant to give pred due
> to low WBC. Treating dehydration and inappetance with SQ fluids and
> mertazapine. ER vet also gave Convenia "just in case?. Going back on Fri to
> my vet for another CBC. Have been following this group for several years
> and want to try Amani?s treatment protocol, but does low WBC contraindicate
> giving prepnisolone and/or Winstrol? Thanks in advance for any advise. - Deb
>
> CBC (21Jul2019)
> NOTE: they did not repeat the analysis which, in hindsight, I should have
> insisted upon
>
> TestResultFlagNormal Range  Measure
> RBC5.11 L 5.65 8.87  M/?L
> HCT24.4L  37.3 61.7   %
> HGB7.8  L  13.1 20.5
>  g/dL
> MCV   47.7L   61.6 73.5  fL
> MCH   15.3L   21.2 25.9  pg
> MCHC 32.0 32.0 37.9
> g/dL
> RDW  23.6H  13.6 21.7  %
> %RETIC 0.2
>   %
> RETIC8.7  L   10.0 110.0
>   K/?L
>
> WBC   * 2.39  5.05 16.76K/?L
> %NEU   

Re: [Felvtalk] Felvtalk Digest, Vol 56, Issue 2

2019-07-25 Thread Deborah Whorley
Thanks Amani. Good advice, hopefully my vet will agree.

Deb

On Thu, Jul 25, 2019 at 10:45  wrote:

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>
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> Today's Topics:
>
>1. Re: Chablis - seeking advise about giving Pred/Doxy/Winstrol
>   with low WBC (Amani Oakley)
>
>
> --
>
> Message: 1
> Date: Thu, 25 Jul 2019 16:45:12 +
> From: Amani Oakley 
> To: "felvtalk@felineleukemia.org" 
> Subject: Re: [Felvtalk] Chablis - seeking advise about giving
> Pred/Doxy/Winstrol with low WBC
> Message-ID:
>  >
> Content-Type: text/plain; charset="utf-8"
>
> Hi Deborah
>
> The CBC results are unusual. There is some anemia going on, and there is
> the low white cell count. There is also an elevated monocyte count.
>
> Most people are aware that white cells go up with an infection, but they
> can also go quite low with an infection ? often if there is a focal area of
> inflammation/infection and white cells are moving out of the circulatory
> system to go to the site of infection in the tissues. My worry is that
> there ma be a source of infection somewhere. Monocytes can be elevated with
> a chronic infection as well.
>
> If it were my cat, I think I might ask the vets to give more in the way of
> antibiotics, with a broad enough spectrum to cover Gram positive and Gram
> negative organisms. I think I might insist on using Doxycycline along with
> another antibiotic, because the Doxycycline also has an effect on some more
> unusual organisms like some parasites and some viruses even. I think I
> would also try the Winstrol if it were me. Winstrol has an excellent
> enhancing effect on appetite, and may also help with the anemia. I myself
> wouldn?t be that worried about the prednisone/prednisolone but it probably
> wouldn?t hurt to hold off on that one and see if you get some improvement
> on the Doxycycline/Other Antibiotic/Winstrol combination.
>
> Amani
>
> From: Felvtalk  On Behalf Of Deborah
> Whorley
> Sent: July 25, 2019 2:59 AM
> To: felvtalk@felineleukemia.org
> Subject: [Felvtalk] Chablis - seeking advise about giving
> Pred/Doxy/Winstrol with low WBC
>
> Hi - one of my FeLV+ cats, Chablis (F, 5 yrs), has been dealing with
> constipation since Jan of this year. Last week she stopped eating like she
> does when she is ?backed up? but 100 cc SQ fluids didn?t resolve the issue
> as it normally does. She also started wheezing Sat eve.  I ended up with
> her in the emergency clinic on Sun and to my surprise her CBC was terrible
> (see below). Radiograph revealed no constipation or obvious masses in
> lungs/abdomen. ER vet, and my vet the next day, reluctant to give pred due
> to low WBC. Treating dehydration and inappetance with SQ fluids and
> mertazapine. ER vet also gave Convenia "just in case?. Going back on Fri to
> my vet for another CBC. Have been following this group for several years
> and want to try Amani?s treatment protocol, but does low WBC contraindicate
> giving prepnisolone and/or Winstrol? Thanks in advance for any advise. - Deb
>
> CBC (21Jul2019)
> NOTE: they did not repeat the analysis which, in hindsight, I should have
> insisted upon
>
> TestResultFlagNormal Range  Measure
> RBC5.11 L 5.65 8.87  M/?L
> HCT24.4L  37.3 61.7   %
> HGB7.8  L  13.1 20.5
>  g/dL
> MCV   47.7L   61.6 73.5  fL
> MCH   15.3L   21.2 25.9  pg
> MCHC 32.0 32.0 37.9
> g/dL
> RDW  23.6H  13.6 21.7  %
> %RETIC 0.2
>   %
> RETIC8.7  L   10.0 110.0
>   K/?L
>
> WBC   * 2.39  5.05 16.76K/?L
> %NEU* 32.6
>  %
> %LYM* 36.8
>  %
> %MONO * 28.5
>   %
> %EOS * 0.4
>   

[Felvtalk] Chablis - seeking advise about giving Pred/Doxy/Winstrol with low WBC

2019-07-25 Thread Deborah Whorley
Hi - one of my FeLV+ cats, Chablis (F, 5 yrs), has been dealing with
constipation since Jan of this year. Last week she stopped eating like she
does when she is “backed up” but 100 cc SQ fluids didn’t resolve the issue
as it normally does. She also started wheezing Sat eve.  I ended up with
her in the emergency clinic on Sun and to my surprise her CBC was terrible
(see below). Radiograph revealed no constipation or obvious masses in
lungs/abdomen. ER vet, and my vet the next day, reluctant to give pred due
to low WBC. Treating dehydration and inappetance with SQ fluids and
mertazapine. ER vet also gave Convenia "just in case”. Going back on Fri to
my vet for another CBC. Have been following this group for several years
and want to try Amani’s treatment protocol, but does low WBC contraindicate
giving prepnisolone and/or Winstrol? Thanks in advance for any advise. - Deb

CBC (21Jul2019)
NOTE: they did not repeat the analysis which, in hindsight, I should have
insisted upon

Test  Result  Flag  Normal Range  Measure
RBC  5.11   L  5.65 8.87 M/μL
HCT  24.4  L  37.3 61.7  %
HGB  7.8  L  13.1 20.5  g/dL
MCV  47.7  L   61.6 73.5  fL
MCH  15.3  L   21.2 25.9  pg
MCHC  32.0   32.0 37.9  g/dL
RDW  23.6  H   13.6 21.7  %
%RETIC  0.2  %
RETIC  8.7  L   10.0 110.0  K/μL

WBC  * 2.39   5.05 16.76  K/μL
%NEU  * 32.6  %
%LYM  * 36.8  %
%MONO * 28.5  %
%EOS  * 0.4  %
%BASO  * 1.7  %
NEU  --.--  2.95 11.64  K/μL
BAND  * Suspected
LYM  * 0.88  1.05 5.10K/μL
MONO  * 0.68  0.16 1.12   K/μL
EOS  * 0.01  0.06 1.23  K/μL
BASO  * 0.04  0.00 0.10  K/μL
nRBC  * Suspected
PLT  * 182  148 484  K/μL
MPV  17.6  H  8.7 13.2  fL
PDW  --.--  9.1 19.4  fL
PCT  0.32 0.14 0.46  %
___
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Re: [Felvtalk] Felvtalk Digest, Vol 47, Issue 6

2018-06-08 Thread Deborah Whorley
Latest discussion from this group. Start at the bottom. There were other
-- Forwarded message --
From: 
Date: Fri, Jun 8, 2018 at 1:22 PM
Subject: Felvtalk Digest, Vol 47, Issue 6
To: felvtalk@felineleukemia.org


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Today's Topics:

   1. Re: Quentin (Marlene Snowman)


--

Message: 1
Date: Fri, 08 Jun 2018 16:22:18 -0300
From: Marlene Snowman 
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Quentin
Message-ID: <14d133e6-4407-4d32-9bb0-e90919acf...@icloud.com>
Content-Type: text/plain; charset="utf-8"

Thank you, I appreciate this.

Marlene

Sent from my iPhone

> On Jun 8, 2018, at 3:48 PM, Amani Oakley  wrote:
>
> In my world, my perspective is usually, it can?t hurt. I would at least
get her on the Doxycycline. It might help with the other problems you are
having, or not, but I would probably give it a try if it were me. The only
thing to watch with the Doxycycline is that the hard tablets have been
known to get stuck in a cat?s throat and cause burning of the eosophagus. I
have never had that problem but I have heard others speak of it. If that is
a concern and all you can get are hard tablets, rub them in butter before
giving them and ensure that the cat is given some yummy canned food
afterwards to ensure that the pill goes down properly. Others have
mentioned you can get Doxycycline in liquid form as well. I suspect that
the problem has been blown out of proportion to the amount of time it
actually occurs, and just like what happened with Winstrol and the link
between it and liver damage, it has improperly curtailed the use of
Doxycycline. I have found Doxycycline (a tetracycline) to ha
 ve a truly remarkable range of effectiveness, so with any luck, it may
address whatever is causing the other nose and eye infections.
>
> Amani
>
> From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of
Marlene Snowman
> Sent: June-08-18 2:39 PM
> To: felvtalk@felineleukemia.org
> Subject: Re: [Felvtalk] Quentin
>
> Thank you Amani for all of this. My little girl, Bear has never gotten
rid of a nose infection. And about 1.5 months ago developed an eye and more
extreme nose infection. The vet prescribed an antibiotic for 7 days and
then every week thereafter 2 to 3 days of this same oral antibiotic.
>
> The nose infection, clears for a few days and then starts back. She has
no issue with appetite or anything else. Unfortunately the vet has never
been able to really examine her as she is so angry and wild with other
people.
>
> That being said, I?m not sure if things are just the way she has always
been, with this chronic nose infection that she has never cleared or
something else further developing. Either way, thus antibiotic isn?t
working on eliminating this issue. And to your point and your experience
with Zander, maybe now is the time for me to get this protocol going before
something further or a worsening.
>
> Thoughts ?
> M
>
>
>
>
> Sent from my iPhone
>
> On Jun 8, 2018, at 3:04 PM, Amani Oakley  wrote:
>
> Hi Marlene
>
> I am not sure about a 3 year old. I think if he/she is stable and having
no problems, I wouldn?t be too concerned.
>
> I would be more worried about a kitten, since they have very little
reserves. Moreover, generally speaking, FeLV is known to be more
problematic for kittens, then it is for older cats. As I have mentioned in
other posts, when my cat Zander was diagnosed with FeLV (and he too was a
very sickly little kitten when we first got him ? worms, leaking nose,
runny diarrhea and almost blind with gunk in both eyes), he lived in our
house with at least 8 other cats for more than 7 years and no one else got
it.
>
> With Zander, we had an initial episode in June where he got very sick,
and his blood counts were terrible, and then he seemed to recover. Getting
no advice otherwise from the vets, other than the fact that he was FeLV
positive, we were relieved and happy that he seemed to be okay. He wasn?t
treated with anything after the first bout of illness. Then it came back
with a vengeance in September (with haematocrit at FIVE compared to a
normal of 25 to 45), and from September and from September to December, we
fought to keep him alive, with blood transfusions and trying every option
out there ? LTCI, interferon, etc. He was also receiving Doxycycline and
prednisone at that time. It wasn?t until I added the Winstrol at the end of
December, did we get a startlin