This doesn't seem to deal at all with the significance of a negative IFA
test after a positive Elisa. It only refers to a positive IFA test.
On 6/15/2011 3:32 PM, Natalie wrote:
Interesting flow chart! A good one to print and keep!
I posted this recently; it also helps to understand the difference between
ELISA and IFA.\
http://www.natural-cat-health-remedies.com/feline-leukemia-test.html
Natalie
-Original Message-
From: felvtalk-boun...@felineleukemia.org
[mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of Sharyl
Sent: Wednesday, June 15, 2011 3:53 PM
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Elisa/IFA clarification
There has been a lot of posts on this subject. This is the link to a flow
chart showing what to do when you get a test result.
http://www.felineleukemia.org/felvhlth.html
It also states when to retest and what test to do. I've found it very helpful.
Sharyl
From: Barb Moermondmr_mok...@yahoo.com
To: felvtalk@felineleukemia.org
Sent: Wednesday, June 15, 2011 11:55 AM
Subject: [Felvtalk] Elisa/IFA clarification
I asked my vets for clarification on the significance of these two tests and
here is their response.
Here is the information from the Cornell University website about Feline
Leukemia stages and testing. If you would like more information, you can go to
their link athttp://www.vet.cornell.edu/fhc/brochures/felv.html
I understand there are two stages of FeLV infection. What are they?
FeLV is present in the blood (a condition called viremia) during two different
stages of infection:
· Primary viremia, an early stage of virus infection. During this stage
some cats are able to mount an effective immune response, eliminate the virus
from the bloodstream, and halt progression to the secondary viremia stage.
· Secondary viremia, a later stage characterized by persistent infection
of the bone marrow and other tissue. If FeLV infection progresses to this stage
it has passed a point of no return: the overwhelming majority of cats with
secondary viremia will be infected for the remainder of their lives.
How is infection diagnosed?
Two types of FeLV blood tests are in common use. Both detect a protein component
of the virus as it circulates in the bloodstream.
· ELISA (enzyme-linked immunosorbent assay) and similar tests can be
performed in your veterinarian's office. ELISA-type tests detect both primary
and secondary stages of viremia.
· IFA (indirect immunofluorescent antibody assay) tests must be sent out
to a diagnostic laboratory. IFA tests detect secondary viremia only, so the
majority of positive-testing cats remain infected for life.
Each testing method has strengths and weaknesses. Your veterinarian will likely
suggest an ELISA-type test first, but in some cases, both tests must be
performed—and perhaps repeated—to clarify a cat's true infection
status. Barb+Smoky the House Puma+El Bandito Malito
My cat the clown: paying no mind to whom he should impress. Merely living his
life, doing what pleases him, and making me smile.
- Anonymous
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