[Freesurfer] Cortical thickness difference measurement

2006-06-01 Thread Joao Pereira
Hello again!

Firstly, let me thank you for your precious previous advices, which pointed
me in the right direction.

I have another question for you: I have read your article on Reliability of
MRI cortical thickness measurements and its relation with scanner and field,
and I would like to know what function did you use to subtract the subjects'
average cortical thickness files in order to have a cortical thickness
difference layer. I don't know if this is a very basic question, but I can't
seem to find how to do it with FS.

Thank you!

Joao Pereira

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Re: [Freesurfer] Cortical thickness difference measurement

2006-06-01 Thread Bruce Fischl

Hi Joao,

I think we did all the subtractions and such in matlab. There are .m files 
for reading/writing most of our formats.


cheers,
Bruce

On Thu, 1 Jun 2006, 
Joao Pereira wrote:



Hello again!

Firstly, let me thank you for your precious previous advices, which pointed
me in the right direction.

I have another question for you: I have read your article on Reliability of
MRI cortical thickness measurements and its relation with scanner and field,
and I would like to know what function did you use to subtract the subjects'
average cortical thickness files in order to have a cortical thickness
difference layer. I don't know if this is a very basic question, but I can't
seem to find how to do it with FS.

Thank you!

Joao Pereira

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[Freesurfer] Using cortical segmentation in an anatomy project

2006-06-01 Thread Ivan Blagoev Topolsky
Hello !

I work for the department of Anatomy
(http://www.medecine.unige.ch/GRAC/) in the Centre Médical Universitaire
of the Université de Genève (http://www.unige.ch/).

We're planning to use the FreeSurfer software suite (or more precisely,
the surface-based stream ) in a project that aims to synthesize brain
models for teaching through rapid-prototyping (like 3D-printing) out of
brain MRI, thus by-passing and giving an alternative to using dead human
bodies for teaching.

I have 2 questions relative to this project :
- Does anyone here have recommendations (or references) about MRI
sequence parameters to obtain best contrast for optimal segmentation ?
Our preliminary test data wasn't top quality indeed, and we're planning
to obtain new datasets. Does anyone has some tips to give us ?

- The download page mentions that the source code will be soon released
(https://surfer.nmr.mgh.harvard.edu/fswiki/Download?action=highlightvalue=source+code),
but that we'll have to wait until all non-releasable modules are
replaced with open-source-able ones.
How far has the OS'ing effort gone until now ? Most specifically, which
modules are already OS'able ?
And how much effort remain to be done ? When will we see an OS'ed version ?
Under what license are those sources going to be released ? (GPL, BSD,
other ?)

Thank you and have a nice day.

- Ivan Topolsky -
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Re: [Freesurfer] Using cortical segmentation in an anatomy project

2006-06-01 Thread Nick Schmansky
Ivan,

In response to your first question about sequence parameters for optimal
segmentation, we achieve optimal gm/wm segmentation using the MP-RAGE
sequence protocol.  For info, see Data Requirements section of this
page:

https://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferBeginnersGuide

which should lead you down to this page of parameters used for
structural imaging:

http://www.nmr.mgh.harvard.edu/~andre/Sequences/SagMPR8Min.html

In response to the open-source questions, we are at least six weeks away
from finally releasing the open source code.  The license it will follow
is this:

https://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferOpenSourceLicense

Nick


On Thu, 2006-06-01 at 16:46 +0200, Ivan Blagoev Topolsky wrote:
 Hello !
 
 I work for the department of Anatomy
 (http://www.medecine.unige.ch/GRAC/) in the Centre Médical Universitaire
 of the Université de Genève (http://www.unige.ch/).
 
 We're planning to use the FreeSurfer software suite (or more precisely,
 the surface-based stream ) in a project that aims to synthesize brain
 models for teaching through rapid-prototyping (like 3D-printing) out of
 brain MRI, thus by-passing and giving an alternative to using dead human
 bodies for teaching.
 
 I have 2 questions relative to this project :
 - Does anyone here have recommendations (or references) about MRI
 sequence parameters to obtain best contrast for optimal segmentation ?
 Our preliminary test data wasn't top quality indeed, and we're planning
 to obtain new datasets. Does anyone has some tips to give us ?
 
 - The download page mentions that the source code will be soon released
 (https://surfer.nmr.mgh.harvard.edu/fswiki/Download?action=highlightvalue=source+code),
 but that we'll have to wait until all non-releasable modules are
 replaced with open-source-able ones.
 How far has the OS'ing effort gone until now ? Most specifically, which
 modules are already OS'able ?
 And how much effort remain to be done ? When will we see an OS'ed version ?
 Under what license are those sources going to be released ? (GPL, BSD,
 other ?)
 
 Thank you and have a nice day.
 
 - Ivan Topolsky -
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Re: [Freesurfer] Using cortical segmentation in an anatomy project

2006-06-01 Thread Bruce Fischl

On Thu, 1 Jun 2006, Ivan Blagoev Topolsky wrote:


Hello !

I work for the department of Anatomy
(http://www.medecine.unige.ch/GRAC/) in the Centre Médical Universitaire
of the Université de Genève (http://www.unige.ch/).

We're planning to use the FreeSurfer software suite (or more precisely,
the surface-based stream ) in a project that aims to synthesize brain
models for teaching through rapid-prototyping (like 3D-printing) out of
brain MRI, thus by-passing and giving an alternative to using dead human
bodies for teaching.

I have 2 questions relative to this project :
- Does anyone here have recommendations (or references) about MRI
sequence parameters to obtain best contrast for optimal segmentation ?
Our preliminary test data wasn't top quality indeed, and we're planning
to obtain new datasets. Does anyone has some tips to give us ?



what type of scanners do you have?



- The download page mentions that the source code will be soon released
(https://surfer.nmr.mgh.harvard.edu/fswiki/Download?action=highlightvalue=source+code),
but that we'll have to wait until all non-releasable modules are
replaced with open-source-able ones.
How far has the OS'ing effort gone until now ? Most specifically, which
modules are already OS'able ?
And how much effort remain to be done ? When will we see an OS'ed version ?
Under what license are those sources going to be released ? (GPL, BSD,
other ?)



we're working on it!



Thank you and have a nice day.

- Ivan Topolsky -
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[Freesurfer] directional cosine error?

2006-06-01 Thread Nguyen, Thang Q








Hello all,

I get a directional cosine error when I try to register data
or extract values from them so I tried mri_info and
get this message:



mri_info subj1.img

matfile: only read
256 bytes of name (810698068 specified)



MatlabRead: readHeader returned NULL



WARNING: analyzeRead(): matfile subj1.mat exists but
could not read ...

 may not be matlab4 mat file ... proceeding without it.

-

INFO: could not find subj1.mat file for direction cosine
info.

INFO: use Analyze 7.5 hdr-hist.orient value: 0, transverse unflipped
(default).

INFO: if not valid, please provide the information in
subj1.mat file

-

Volume information for subj1.img


type: analyze4d

 dimensions: 79 x 95 x 68

 voxel sizes: 2., 2.,
2.


type: FLOAT (3)


fov: 79.000


xstart: -39.5, xend: 39.5


ystart: -47.5, yend: 47.5


zstart: -34.0, zend: 34.0


TR: 0.00 msec, TE: 0.00 msec, TI: 0.00 msec, flip angle:
0.00 degrees

 nframes: 1

ras xform present

 xform info: x_r = -1., y_r = 0., z_r = 0., c_r = 0.


: x_a = 0., y_a
= 1., z_a
= 0., c_a
= 0.


: x_s = 0., y_s
= 0., z_s
= 1., c_s
= 0.

Orientation
: LAS

Primary Slice Direction: axial



voxel to ras transform:


-2. 0. 0. 79.


0. 2. 0. -95.


0. 0.
2. -68.


0. 0. 0. 1.



voxel-to-ras determinant
-8



ras to voxel transform:


-0.5000 -0. -0. 39.5000


0. 0.5000 0. 47.5000


0. 0.
0.5000 34.




0. 0. 0. 1.







Here is the mat file:



Subj1

2.00

2.00

200.00

1.054861e+00 -2.348376e-02 -1.086195e-01 7.747378e-01

9.350572e-02 -3.302234e-01 1.067427e+00 -3.124532e+01

-4.640190e-02 -9.299399e-01 -3.056859e-01 -7.546637e+00

0.00e+00 0.00e+00 0.00e+00 1.00e+00

round





What does the matlab error mean? Why cant it read the directional
cosine?







-Thang
















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[Freesurfer] Problems with Auto Reconall

2006-06-01 Thread Frederick Powell

using max gradient = 1.000
  reading from nu.mgz...
  normalizing image...
  talairach transform
   1.117   0.005   0.077  -0.516;
  -0.015   1.062   0.148  -22.126;
  -0.084  -0.173   1.230  -34.192;
   0.000   0.000   0.000   1.000;
  INFO: Modifying talairach volume c_(r,a,s) based on average_305
  building Voronoi diagram...
  performing soap bubble smoothing...
  3d normalization pass 1 of 2
  building Voronoi diagram...
  performing soap bubble smoothing...
  3d normalization pass 2 of 2
  building Voronoi diagram...
  Segmentation fault
  Linux killiany 2.6.9-34.ELsmp #1 SMP Wed Mar 8 00:27:03 CST 2006 i686
  athlon i386 GNU/Linux
  recon-all exited with ERRORS at Wed May 31 16:54:11 EDT 2006

Above are the errors that I have recieved while trying to run the
  latest version of auto recon.  Please help I am continuously getting
  teh Segmentation Fault error.  I am running 3t MPRAGE images.  Thanks

--
Frederick G. Powell
Boston University School of Medicine
MD/PhD candidate
617-593-7183
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Re: [Freesurfer] Problems with Auto Reconall

2006-06-01 Thread Bruce Fischl

can you run:

mri_info nu.mgz

and send us the results?

thanks,
Bruce

On Thu, 1 Jun 2006, Frederick Powell wrote:


using max gradient = 1.000
 reading from nu.mgz...
 normalizing image...
 talairach transform
  1.117   0.005   0.077  -0.516;
 -0.015   1.062   0.148  -22.126;
 -0.084  -0.173   1.230  -34.192;
  0.000   0.000   0.000   1.000;
 INFO: Modifying talairach volume c_(r,a,s) based on average_305
 building Voronoi diagram...
 performing soap bubble smoothing...
 3d normalization pass 1 of 2
 building Voronoi diagram...
 performing soap bubble smoothing...
 3d normalization pass 2 of 2
 building Voronoi diagram...
 Segmentation fault
 Linux killiany 2.6.9-34.ELsmp #1 SMP Wed Mar 8 00:27:03 CST 2006 i686
 athlon i386 GNU/Linux
 recon-all exited with ERRORS at Wed May 31 16:54:11 EDT 2006

Above are the errors that I have recieved while trying to run the
 latest version of auto recon.  Please help I am continuously getting
 teh Segmentation Fault error.  I am running 3t MPRAGE images.  Thanks



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[Freesurfer] error in 'create surface'

2006-06-01 Thread Joongnam Yang
Hi all,

I posted a question, but for some reason, I didn't get any response.
Please help me on this.
Here is the question.

I ran 'process volume' and 'create surface' on csurf.
The created surface (left inflated) has brain stem attached to it.
So, I editted 'wm' slices to get rid of it, and ran 'create surface' again.
No change took place. 
I tried commandline 'recon-all -stage1 -subjid ID', with no luck.

Would someone suggest any comment on this?

Nam.
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Re: [Freesurfer] error in 'create surface'

2006-06-01 Thread Nick Schmansky
Nam,

The csurf application is no longer supported (and has been removed from
the newest release).  The recon-all script now performs all processing
stages, where the three main stages are -autorecon1, -autorecon2 and -
autorecon3 (-stage1 is a deprecated option).

You may want to see our new tutorial, here:

https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial

to learn what sorts of problems can occur during the various stages. 

It's hard to say from your email what the problem may be, but it could
be a bad Talairach alignment. The tutorial discusses this.  Note: you
should not see the brain stem after the image has been skull-stripped
(which occurs during the -autorecon1 stage).

Nick


On Thu, 2006-06-01 at 14:40 -0400, Joongnam Yang wrote:
 Hi all,
 
 I posted a question, but for some reason, I didn't get any response.
 Please help me on this.
 Here is the question.
 
 I ran 'process volume' and 'create surface' on csurf.
 The created surface (left inflated) has brain stem attached to it.
 So, I editted 'wm' slices to get rid of it, and ran 'create surface' again.
 No change took place. 
 I tried commandline 'recon-all -stage1 -subjid ID', with no luck.
 
 Would someone suggest any comment on this?
 
 Nam.
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Re: [Freesurfer] directional cosine error?

2006-06-01 Thread Doug Greve





If you have a tkregister registration file called subj1.mat, then name
it something else as the volume reading tools think that is an
spm-style .mat file and try to read it as a matlab4 matrix.

doug


Nguyen, Thang Q wrote:

  
  
  
  
  

  
  
  Hello all,
  I get a directional
cosine error when I try to register data
or extract values from them so I tried mri_info
and
get this message:
  
  mri_info subj1.img
  matfile: only read
256 bytes of name (810698068 specified)
  
  MatlabRead: readHeader
returned NULL
  
  WARNING: analyzeRead(): matfile
subj1.mat exists but
could not read ...
   may not be matlab4 mat file ... proceeding
without it.
  -
  INFO: could not find
subj1.mat file for direction cosine
info.
  INFO: use Analyze 7.5 hdr-hist.orient
value: 0, transverse unflipped
(default).
  INFO: if not valid,
please provide the information in
subj1.mat file
  -
  Volume information for
subj1.img
  
  type: analyze4d
  
  dimensions: 79 x 95 x 68
  
  voxel sizes: 2., 2.,
2.
  
  type: FLOAT (3)
  
  fov: 79.000
  
  xstart: -39.5, xend: 39.5
  
  ystart: -47.5, yend: 47.5
  
  zstart: -34.0, zend: 34.0
  
  TR: 0.00 msec, TE: 0.00 msec,
TI: 0.00 msec, flip angle:
0.00 degrees
   nframes: 1
  ras xform
present
   xform info: x_r = -1.,
y_r = 0., z_r = 0.,
c_r = 0.
  
  : x_a
= 0., y_a
= 1., z_a
= 0., c_a
= 0.
  
  : x_s = 0.,
  y_s
= 0., z_s
= 1., c_s
= 0.
  Orientation
  : LAS
  Primary Slice Direction:
axial
  
  voxel to ras
transform:
  
  -2. 0. 0. 79.
  
  0. 2. 0. -95.
  
  0. 0.
  2. -68.
  
  0. 0. 0.
  1.
  
  voxel-to-ras determinant
-8
  
  ras to voxel
transform:
  
  -0.5000 -0. -0. 39.5000
  
  0. 0.5000 0. 47.5000
  
  0. 0.
  0.5000 34.
  
  
  0. 0. 0.
  1.
  
  
  
  Here is the mat file:
  
  Subj1
  2.00
  2.00
  200.00
  1.054861e+00
-2.348376e-02 -1.086195e-01 7.747378e-01
  9.350572e-02
-3.302234e-01 1.067427e+00 -3.124532e+01
  -4.640190e-02
-9.299399e-01 -3.056859e-01 -7.546637e+00
  0.00e+00 0.00e+00 0.00e+00
1.00e+00
  round
  
  
  What does the matlab error mean? Why
cant it read the directional
cosine?
  
  
  
  -Thang
  
  
  
  
  
  
  

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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
[EMAIL PROTECTED]
Phone Number: 617-724-2358 
Fax: 617-726-7422

In order to help us help you, please follow the steps in:
surfer.nmr.mgh.harvard.edu/fswiki/BugReporting




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Re: [Freesurfer] Recon error

2006-06-01 Thread Bruce Fischl

it is in the mri dir:

/Users/frederickpowell/freesurfer/subjects/011106RJ/mri/nu.mgz

On Thu, 1 Jun 
2006, Frederick Powell wrote:



gunzip: /Users/frederickpowell/freesurfer/subjects/011106RJ/nu.mgz.gz:
No such file or directory
mghRead(/Users/frederickpowell/freesurfer/subjects/011106RJ/nu.mgz,
-1): read error

I went into my subjects directory and to the subject that I ran with
the error and received the above.



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[Freesurfer] eTIV bug

2006-06-01 Thread Sasha Wolosin
Dear all,
  I have processed all my data using Stable v3.0.1.  Does the eTIV bug
effect any other volume measures?  If I want to compute eTIV for my
data, should I install the lates version and re-run mri_label_volume
-eTIV ?
Thanks,
Sasha



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Re: [Freesurfer] eTIV bug

2006-06-01 Thread Nick Schmansky
Sasha,

The eTIV bug (fixed in v3.0.2) affects mri_label_volume and
mri_segstats.  mri_segstats is run as part of the standard recon-all
stream, and incorporates the eTIV calculation, putting the results in
the file subjid/stats/aseg.stats, the lines beginning with:

# Measure .

So you would need to rerun mri_segstats using a newer version.  If you
prefer, I could send you the binary for your installation (rather than
re-install all of freesurfer).

Nick


On Thu, 2006-06-01 at 16:21 -0400, Sasha Wolosin wrote:
 Dear all,
   I have processed all my data using Stable v3.0.1.  Does the eTIV bug
 effect any other volume measures?  If I want to compute eTIV for my
 data, should I install the lates version and re-run mri_label_volume
 -eTIV ?
 Thanks,
 Sasha
 
 
 
 Disclaimer:
 The materials in this e-mail are private and may contain Protected Health 
 Information. Please note that e-mail is not necessarily confidential or 
 secure. Your use of e-mail constitutes your acknowledgment of these 
 confidentiality and security limitations. If you are not the intended 
 recipient, be advised that any unauthorized use, disclosure, copying, 
 distribution, or the taking of any action in reliance on the contents of this 
 information is strictly prohibited. If you have received this e-mail in 
 error, please immediately notify the sender via telephone or return e-mail.
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Re: Re: [Freesurfer] error in 'create surface'

2006-06-01 Thread Joongnam Yang
Thanks, Nick,

If I install a new version of FS, would it be too much of hassle?

Because I am in the middle of data analysis for a project using the
old version, and I remember I had a big trouble installing different
libraries for Freesurfer for the old version, which was a daunting job.
 
Nam.

 Nick Schmansky [EMAIL PROTECTED] 06/06/01 오후 2:54 
Nam,

The csurf application is no longer supported (and has been removed from
the newest release).  The recon-all script now performs all processing
stages, where the three main stages are -autorecon1, -autorecon2 and -
autorecon3 (-stage1 is a deprecated option).

You may want to see our new tutorial, here:

https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial

to learn what sorts of problems can occur during the various stages. 

It's hard to say from your email what the problem may be, but it could
be a bad Talairach alignment. The tutorial discusses this.  Note: you
should not see the brain stem after the image has been skull-stripped
(which occurs during the -autorecon1 stage).

Nick


On Thu, 2006-06-01 at 14:40 -0400, Joongnam Yang wrote:
 Hi all,
 
 I posted a question, but for some reason, I didn't get any response.
 Please help me on this.
 Here is the question.
 
 I ran 'process volume' and 'create surface' on csurf.
 The created surface (left inflated) has brain stem attached to it.
 So, I editted 'wm' slices to get rid of it, and ran 'create surface'
again.
 No change took place. 
 I tried commandline 'recon-all -stage1 -subjid ID', with no luck.
 
 Would someone suggest any comment on this?
 
 Nam.
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Re: Re: [Freesurfer] error in 'create surface'

2006-06-01 Thread Nick Schmansky
Nam,

The newer versions of freesurfer (those within the past year) contain
the major libraries and toolkits upon which freesurfer depends
(Tcl/Tk/Tix/BLT, GSL, MNI, FSL), so it should be straightforward to
install a new version.  See:

http://surfer.nmr.mgh.harvard.edu/fswiki/Download

Basicaly, just get the tarball, untar anywhere (for example,
to /usr/local), and put this in your .cshrc file:

  setenv FREESURFER_HOME /usr/local/freesurfer
  source $FREESURFER_HOME/SetUpFreeSurfer.csh

Nick


On Thu, 2006-06-01 at 17:27 -0400, Joongnam Yang wrote:
 Thanks, Nick,
 
 If I install a new version of FS, would it be too much of hassle?
 
 Because I am in the middle of data analysis for a project using the
 old version, and I remember I had a big trouble installing different
 libraries for Freesurfer for the old version, which was a daunting job.
  
 Nam.
 
  Nick Schmansky [EMAIL PROTECTED] 06/06/01 오후 2:54 
 Nam,
 
 The csurf application is no longer supported (and has been removed from
 the newest release).  The recon-all script now performs all processing
 stages, where the three main stages are -autorecon1, -autorecon2 and -
 autorecon3 (-stage1 is a deprecated option).
 
 You may want to see our new tutorial, here:
 
 https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial
 
 to learn what sorts of problems can occur during the various stages. 
 
 It's hard to say from your email what the problem may be, but it could
 be a bad Talairach alignment. The tutorial discusses this.  Note: you
 should not see the brain stem after the image has been skull-stripped
 (which occurs during the -autorecon1 stage).
 
 Nick
 
 
 On Thu, 2006-06-01 at 14:40 -0400, Joongnam Yang wrote:
  Hi all,
  
  I posted a question, but for some reason, I didn't get any response.
  Please help me on this.
  Here is the question.
  
  I ran 'process volume' and 'create surface' on csurf.
  The created surface (left inflated) has brain stem attached to it.
  So, I editted 'wm' slices to get rid of it, and ran 'create surface'
 again.
  No change took place. 
  I tried commandline 'recon-all -stage1 -subjid ID', with no luck.
  
  Would someone suggest any comment on this?
  
  Nam.
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[Freesurfer] How to disable jumping tool windows? Environment variables?

2006-06-01 Thread Graham Wideman

Folks:

Both tkmedit and tksurfer have tool windows which jump to a location below 
their respective main image windows whenever the image windows are moved or 
adjusted.


This prevents the image windows from being enlarged to full screen height, 
because the tool windows then jump to bottom of screen, and behind the main 
window.


Is there some way to signal these two apps not to move the tool windows?

Also, if there is such a setting I'm suspecting it would be an environment 
variable.  I looked at the Wiki, but didn't find a listing of useful 
environment variables -- is there one to be had?


Thanks,

Graham

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Re: [Freesurfer] How to disable jumping tool windows? Environment variables?

2006-06-01 Thread Kevin Teich
 Both tkmedit and tksurfer have tool windows which jump to a location below 
 their respective main image windows whenever the image windows are moved or 
 adjusted.
 
 This prevents the image windows from being enlarged to full screen height, 
 because the tool windows then jump to bottom of screen, and behind the main 
 window.
 
 Is there some way to signal these two apps not to move the tool windows?

Sorry, no, that's a feature. :)

If you're only doing volume viewing and don't need surface viewing or
some of the other esoteric tkmedit tools, you may want to try scuba,
which works much better when enlarged to full-screen size.



-- 
Kevin Teich
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