Re: [Freesurfer] absolute value of effect size

2014-01-08 Thread Douglas N Greve

You can do it to the sig file (the p-value already assumes a two-sided 
test). Why do you want to do it with the ces and cesvar files? If you 
are planning to use the abs(ces) for a higher level analysis then you 
need to be very careful as you can get some unintended effects
doug




On 01/07/2014 03:46 PM, SHAHIN NASR wrote:
 Hi,
 I have two related questions.  I have two conditions (e.g. C1 and 
 C2) and I want to generate a map that shows all voxels that can 
 differentiate C1 from C2 _irrespective_ of whether C1C2 or C1C2.  I 
 think it can be done easily by:

 mris_calc -o sig.nii abs_sig.nii abs

 If I am right, then:
 1) Can I apply the same command to ces.nii file to have the absolute 
 value of the effect size (i.e. abs(C1-C2 effect size)) or should I 
 consider other factors?
 2) Do I need to apply the same routine to cesvar?

 Thanks
 -- 
 Shahin Nasr

 PhD in Cognitive Neuroscience
 Martinos Imaging Center, MGH
 Harvard Medical School

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

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Re: [Freesurfer] absolute value of effect size

2014-01-08 Thread Douglas N Greve

Several potential problems. It makes the statistics non-gaussian and the 
abs(ces) becomes noise dependent (and so there will be a noise dependent 
bias). This makes interpretation more difficult (eg, is a difference 
between groups a difference in ces or a difference in noise?). The 
non-gaussianity could be addressed with a permutation test.



doug





On 01/08/2014 07:11 PM, sha...@nmr.mgh.harvard.edu wrote:
 Exactly! I need ces and cesvar files for a second order analysis.  More
 specifically, I need to subtract this absolute map from another map.
 Would you be more specific about what I should check when I am doing this
 second order analysis?



 You can do it to the sig file (the p-value already assumes a two-sided
 test). Why do you want to do it with the ces and cesvar files? If you
 are planning to use the abs(ces) for a higher level analysis then you
 need to be very careful as you can get some unintended effects
 doug




 On 01/07/2014 03:46 PM, SHAHIN NASR wrote:
 Hi,
  I have two related questions.  I have two conditions (e.g. C1 and
 C2) and I want to generate a map that shows all voxels that can
 differentiate C1 from C2 _irrespective_ of whether C1C2 or C1C2.  I
 think it can be done easily by:

 mris_calc -o sig.nii abs_sig.nii abs

  If I am right, then:
 1) Can I apply the same command to ces.nii file to have the absolute
 value of the effect size (i.e. abs(C1-C2 effect size)) or should I
 consider other factors?
 2) Do I need to apply the same routine to cesvar?

 Thanks
 --
 Shahin Nasr

 PhD in Cognitive Neuroscience
 Martinos Imaging Center, MGH
 Harvard Medical School
 --
 Douglas N. Greve, Ph.D.
 MGH-NMR Center
 gr...@nmr.mgh.harvard.edu
 Phone Number: 617-724-2358
 Fax: 617-726-7422

 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
 FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
 www.nmr.mgh.harvard.edu/facility/filedrop/index.html
 Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/





-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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[Freesurfer] absolute value of effect size

2014-01-07 Thread SHAHIN NASR
Hi,
I have two related questions.  I have two conditions (e.g. C1 and C2)
and I want to generate a map that shows all voxels that can differentiate
C1 from C2 *irrespective* of whether C1C2 or C1C2.  I think it can be
done easily by:

mris_calc -o sig.nii abs_sig.nii abs

If I am right, then:
1) Can I apply the same command to ces.nii file to have the absolute value
of the effect size (i.e. abs(C1-C2 effect size)) or should I consider other
factors?
2) Do I need to apply the same routine to cesvar?

Thanks
-- 
Shahin Nasr

PhD in Cognitive Neuroscience
Martinos Imaging Center, MGH
Harvard Medical School
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http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.