Dear Christian,
They atlas is built using subfield segmentations on scans of older adult
brains, but:
1. it’s also built with whole hippocampus segmentations of scans of subjects of
a wider age range.
2. the deformation model should be able to account for large parts of the
anatomical differences between subjects of different ages.
> I would think this would be an issue for young kids that have markedly
> different brain volumes, but not for older kids and young adults that differ
> less dramatically from older adults.
I agree with this statement.
I hope this helps!
/Eugenio
--
Juan Eugenio Iglesias
ERC Senior Research Fellow
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/
From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Christian Krog
Tamnes <c.k.tam...@psykologi.uio.no>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Wednesday, 10 January 2018 at 11:33
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] hippocampal subfields in younger populations
Dear FreeSurfer and hippocampal subfield segmentation developers,
I have noted that the FS6.0 hippocampal subfield segmentation procedure was
developed using scans of older adult brains. Has the application of this method
to kids, adolescents and/or young adults in any way been validated? Or do you
have any thoughts regarding such use of the method?
I would think this would be an issue for young kids that have markedly
different brain volumes, but not for older kids and young adults that differ
less dramatically from older adults. But I would greatly appreciate any input
regarding this.
Best regards,
Christian
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