[Histonet] Minimum sample size for breast markers
Is there a minimum number of cells that should be present when testing for ER, PR and Her2? I have looked on the CAP website but cannot see anything about this. We are constantly getting these small biopsies or FNAs for testing and I sometimes wonder what the lowest threshold is for testing...20 tumor cells, 50 tumor cells Any information would be appreciated. Thanks in advance for your help. Martha Ward, MT (ASCP) QIHC Manager Molecular Diagnostics Lab Medical Center Boulevard \ Winston-Salem, NC 27157 p 336.716.2109 \ f 336.716.5890 mw...@wakehealth.edu ___ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet
RE: [Histonet] Minimum sample size for breast markers
Thanks everyone From: Rene J Buesa [mailto:rjbu...@yahoo.com] Sent: Thursday, September 12, 2013 10:56 AM To: Martha Ward-Pathology; histonet@lists.utsouthwestern.edu Subject: Re: [Histonet] Minimum sample size for breast markers No, there are no written instructions on the subject. You just have to state how many cells you found and the clinician is supposed to act accordingly. René J. From: Martha Ward-Pathology mw...@wakehealth.edumailto:mw...@wakehealth.edu To: Rene J Buesa rjbu...@yahoo.commailto:rjbu...@yahoo.com; histonet@lists.utsouthwestern.edumailto:histonet@lists.utsouthwestern.edu histonet@lists.utsouthwestern.edumailto:histonet@lists.utsouthwestern.edu Sent: Thursday, September 12, 2013 10:24 AM Subject: RE: [Histonet] Minimum sample size for breast markers Thanks Rene. I realize that it is ultimately up to the Pathologist but I was wondering if there are any written guideline/suggestions because I have had pathologists ask me if there is minimum. From: Rene J Buesa [mailto:rjbu...@yahoo.com] Sent: Thursday, September 12, 2013 9:23 AM To: Martha Ward-Pathology; histonet@lists.utsouthwestern.edumailto:histonet@lists.utsouthwestern.edu Subject: Re: [Histonet] Minimum sample size for breast markers I do not think this is the adequate forum to ask this question because you may get a wrong answer that could determine your decision. Your pathologist is the one who should decide about this issue. René J. From: Martha Ward-Pathology mw...@wakehealth.edumailto:mw...@wakehealth.edu To: histonet@lists.utsouthwestern.edumailto:histonet@lists.utsouthwestern.edu histonet@lists.utsouthwestern.edumailto:histonet@lists.utsouthwestern.edu Sent: Thursday, September 12, 2013 9:06 AM Subject: [Histonet] Minimum sample size for breast markers Is there a minimum number of cells that should be present when testing for ER, PR and Her2? I have looked on the CAP website but cannot see anything about this. We are constantly getting these small biopsies or FNAs for testing and I sometimes wonder what the lowest threshold is for testing...20 tumor cells, 50 tumor cells Any information would be appreciated. Thanks in advance for your help. Martha Ward, MT (ASCP) QIHC Manager Molecular Diagnostics Lab Medical Center Boulevard \ Winston-Salem, NC 27157 p 336.716.2109 \ f 336.716.5890 mw...@wakehealth.edumailto:mw...@wakehealth.edu ___ Histonet mailing list Histonet@lists.utsouthwestern.edumailto:Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet ___ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet
Re: [Histonet] Minimum sample size for breast markers
No, there are no written instructions on the subject. You just have to state how many cells you found and the clinician is supposed to act accordingly. René J. From: Martha Ward-Pathology mw...@wakehealth.edu To: Rene J Buesa rjbu...@yahoo.com; histonet@lists.utsouthwestern.edu histonet@lists.utsouthwestern.edu Sent: Thursday, September 12, 2013 10:24 AM Subject: RE: [Histonet] Minimum sample size for breast markers Thanks Rene. I realize that it is ultimately up to the Pathologist but I was wondering if there are any written guideline/suggestions because I have had pathologists ask me if there is minimum. From:Rene J Buesa [mailto:rjbu...@yahoo.com] Sent: Thursday, September 12, 2013 9:23 AM To: Martha Ward-Pathology; histonet@lists.utsouthwestern.edu Subject: Re: [Histonet] Minimum sample size for breast markers I do not think this is the adequate forum to ask this question because you may get a wrong answer that could determine your decision. Your pathologist is the one who should decide about this issue. RenéJ. From:Martha Ward-Pathology mw...@wakehealth.edu To: histonet@lists.utsouthwestern.edu histonet@lists.utsouthwestern.edu Sent: Thursday, September 12, 2013 9:06 AM Subject: [Histonet] Minimum sample size for breast markers Is there a minimum number of cells that should be present when testing for ER, PR and Her2? I have looked on the CAP website but cannot see anything about this. We are constantly getting these small biopsies or FNAs for testing and I sometimes wonder what the lowest threshold is for testing...20 tumor cells, 50 tumor cells Any information would be appreciated. Thanks in advance for your help. Martha Ward, MT (ASCP) QIHC Manager Molecular Diagnostics Lab Medical Center Boulevard \ Winston-Salem, NC 27157 p 336.716.2109 \ f 336.716.5890 mw...@wakehealth.edu ___ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet ___ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet
