GlaxoSmithKline (GSK) has an exciting position for a highly motivated Quantitative Clinical Pharmacologist to join our London team as a member of the global department of Clinical Pharmacology Modelling & Simulation. The job level will depend on the skills and achievements of the successful candidate. This is an excellent opportunity to use quantitative clinical pharmacology to accelerate the delivery of new medicines to patients by enhancing drug program efficiency and business decision quality. Responsibilities: * Plan, execute and report translational drug-disease modelling, exposure-response analysis, simulation-based trial design and population clinical pharmacology * Contribute to asset clinical development and registration in terms of program plans, trial protocols, analysis plans, study reports and regulatory submissions * Assess and apply innovative techniques such as longitudinal exposure-response analysis, model-based meta-analysis and item-response analysis to maximise data use, trial efficiency and analytical power * Present strategy and discuss outcome of model-based approaches during interactions with internal governance boards and regulators * Promote model-informed drug discovery and development through external collaboration, journal publication and conference presentation
Requirements: * A doctorate in a field relevant to quantitative clinical pharmacology, and experience in using modelling/simulation to solve practical problems in industry or academia * Proven skills in pharmacokinetic-pharmacodynamic and longitudinal disease modelling; and verifiable proficiency in pharmacometric tools NONMEM, Monolix, R or SAS * Strong drive and learning agility to quickly build knowledge on a drug-disease system, symptom progression, trial design/endpoints and current treatments * Demonstrated aptitude for productive collaboration in a multi-discipline team, using effective communication and taking personal accountability for timely delivery of results * Clear evidence of ability to make sound judgement in complex situations and adapt to changing business needs by prioritising multiple tasks At GSK, we develop therapies of various modalities for a broad range of indications. As a member of a global department with diverse expertise, you will enjoy a highly supportive environment for scientific innovation, business impact and professional growth. Interested persons are encouraged to apply online here<https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=406201&localeCode=en-us>. Chao Chen Clinical Pharmacology Modelling & Simulation GlaxoSmithKline R&D GSK monitors email communications sent to and from GSK in order to protect GSK, our employees, customers, suppliers and business partners, from cyber threats and loss of GSK Information. GSK monitoring is conducted with appropriate confidentiality controls and in accordance with local laws and after appropriate consultation. ________________________________ This e-mail was sent by GlaxoSmithKline Services Unlimited (registered in England and Wales No. 1047315), which is a member of the GlaxoSmithKline group of companies. The registered address of GlaxoSmithKline Services Unlimited is 980 Great West Road, Brentford, Middlesex TW8 9GS.
