[ozmidwifery] Article about preterm birth and treatment for cervical changes
Precancerous changes and preterm births Issue 01: 8 Jan 2007 Source: BJOG: An International Journal of Obstetrics and Gynaecology 2007;114:70-80 A study has provided new insights into the association between precancerous changes in the cervix and the risk of subsequent preterm birth. The findings suggest that diagnosis of precancerous changes, regardless of the treatment given, is associated with a significantly increased risk of delivery before 37 weeks' gestation. Researchers at centers in Carlton, Australia, conducted a retrospective cohort study, investigating the records of 5,548 women who: 1.. Were referred to a cervical dysplasia clinic at the Royal Women's Hospital in Carlton between 1982 and 2000 for assessment of an abnormality detected on a routine Pap smear or for evaluation of a cervix that appeared abnormal; and 2.. Subsequently had a birth recorded in the Victoria state perinatal data collection system. The birth studied was the first after the referral, for women who were untreated, and the first after treatment, for women who received treatment. The follow-up period for the women ranged from 2 years to 20 years after referral. The researchers report their findings in a new paper published in the BJOG: An International Journal of Obstetrics and Gynaecology. Overall, there were 533 observed preterm births in the cohort of 5,548 women, significantly higher than the 312 cases expected based on national figures. The main findings included the following: a.. The risk of preterm birth (defined as within 37 weeks of gestation) was significantly higher for both treated and untreated women compared with the general population. b.. The risk of preterm birth was significantly higher among the treated women than among the untreated women. c.. Other factors significantly associated with an increased risk of preterm birth were a history of induced or spontaneous abortion, illicit drug use during pregnancy, and a major maternal medical condition. In terms of treatment, cone biopsy, loop electrosurgical excision procedure (LEEP), and diathermy were associated with preterm birth; after adjustment for potentially confounding factors, only the association between diathermy and preterm birth remained statistically significant. d.. Women treated with laser ablation did not have a significantly increased risk of preterm birth. Discussing their findings, the researchers say the study is the largest to date examining pregnancy outcomes following diagnosis and treatment for precancerous changes in the cervix. They conclude: Women presenting with precancerous changes in the cervix are at an increased risk for preterm birth, a risk that appears to be increased by treatments that remove or destroy substantial amounts of cervical tissue. They suggest that, in light of these findings, there needs to be a re-evaluation of treatment programmes involving a see and treat policy for the management of abnormal Pap smear results. In addition, the use of ablative techniques such as laser ablation need revisiting, the researchers state.
RE: [ozmidwifery] Article about preterm birth and treatment for cervical changes
Dear all Twice in one night out of two years I feel compelled to answer posts on the list! This study has been used as a propellar for inaugerating new studies performed on the pregnant here in Denmark! Actually they claim to have a vaccine given to young girls up to 15 years old, that would solve this problem. I have great dificulties getting totally convinced a vaccine could solve this particular cancer problem. And this at a moment where the National Health Institute finally has acknowledged major problems with screening of breast cancer and the like (a.o. Down's Syndrome), because of poor results as to positive/negative readings followed by distress due to trauma caused by the readings. What is really the agenda? Kirsten in Denmark -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Helen and Graham Sent: 10. januar 2007 23:04 To: ozmidwifery Subject: [ozmidwifery] Article about preterm birth and treatment for cervical changes Precancerous changes and preterm births Issue 01: 8 Jan 2007 Source: BJOG: An International Journal of Obstetrics and Gynaecology 2007;114:70-80 A study has provided new insights into the association between precancerous changes in the cervix and the risk of subsequent preterm birth. The findings suggest that diagnosis of precancerous changes, regardless of the treatment given, is associated with a significantly increased risk of delivery before 37 weeks gestation. Researchers at centers in Carlton, Australia, conducted a retrospective cohort study, investigating the records of 5,548 women who: 1. Were referred to a cervical dysplasia clinic at the Royal Womens Hospital in Carlton between 1982 and 2000 for assessment of an abnormality detected on a routine Pap smear or for evaluation of a cervix that appeared abnormal; and 2. Subsequently had a birth recorded in the Victoria state perinatal data collection system. The birth studied was the first after the referral, for women who were untreated, and the first after treatment, for women who received treatment. The follow-up period for the women ranged from 2 years to 20 years after referral. The researchers report their findings in a new paper published in the BJOG: An International Journal of Obstetrics and Gynaecology. Overall, there were 533 observed preterm births in the cohort of 5,548 women, significantly higher than the 312 cases expected based on national figures. The main findings included the following: * The risk of preterm birth (defined as within 37 weeks of gestation) was significantly higher for both treated and untreated women compared with the general population. * The risk of preterm birth was significantly higher among the treated women than among the untreated women. * Other factors significantly associated with an increased risk of preterm birth were a history of induced or spontaneous abortion, illicit drug use during pregnancy, and a major maternal medical condition. In terms of treatment, cone biopsy, loop electrosurgical excision procedure (LEEP), and diathermy were associated with preterm birth; after adjustment for potentially confounding factors, only the association between diathermy and preterm birth remained statistically significant. * Women treated with laser ablation did not have a significantly increased risk of preterm birth. Discussing their findings, the researchers say the study is the largest to date examining pregnancy outcomes following diagnosis and treatment for precancerous changes in the cervix. They conclude: Women presenting with precancerous changes in the cervix are at an increased risk for preterm birth, a risk that appears to be increased by treatments that remove or destroy substantial amounts of cervical tissue. They suggest that, in light of these findings, there needs to be a re-evaluation of treatment programmes involving a see and treat policy for the management of abnormal Pap smear results. In addition, the use of ablative techniques such as laser ablation need revisiting, the researchers state.
Re: [ozmidwifery] Article about preterm birth and treatment for cervical changes
MessageHi Kirsten, Are you talking about the HPV (genital warts) vaccine? They say HPV is responsible for approx 70% of cervical cancer cases although I have seen that figure stretched beyond the 70% for the sake of advertising of the HPV vaccine. I'm not sure where the figure comes from. I would say money figures heavily on the agenda :) The vaccine is now available in Australia and the US. I'm not sure where else at present. Regards Jayne - Original Message - From: Kirsten Lerstrøm To: ozmidwifery@acegraphics.com.au Sent: Thursday, January 11, 2007 10:19 AM Subject: RE: [ozmidwifery] Article about preterm birth and treatment for cervical changes Dear all Twice in one night out of two years I feel compelled to answer posts on the list! This study has been used as a propellar for inaugerating new studies performed on the pregnant here in Denmark! Actually they claim to have a vaccine given to young girls up to 15 years old, that would solve this problem. I have great dificulties getting totally convinced a vaccine could solve this particular cancer problem. And this at a moment where the National Health Institute finally has acknowledged major problems with screening of breast cancer and the like (a.o. Down's Syndrome), because of poor results as to positive/negative readings followed by distress due to trauma caused by the readings. What is really the agenda? Kirsten in Denmark -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Helen and Graham Sent: 10. januar 2007 23:04 To: ozmidwifery Subject: [ozmidwifery] Article about preterm birth and treatment for cervical changes Precancerous changes and preterm births Issue 01: 8 Jan 2007 Source: BJOG: An International Journal of Obstetrics and Gynaecology 2007;114:70-80 A study has provided new insights into the association between precancerous changes in the cervix and the risk of subsequent preterm birth. The findings suggest that diagnosis of precancerous changes, regardless of the treatment given, is associated with a significantly increased risk of delivery before 37 weeks' gestation. Researchers at centers in Carlton, Australia, conducted a retrospective cohort study, investigating the records of 5,548 women who: 1.. Were referred to a cervical dysplasia clinic at the Royal Women's Hospital in Carlton between 1982 and 2000 for assessment of an abnormality detected on a routine Pap smear or for evaluation of a cervix that appeared abnormal; and 2.. Subsequently had a birth recorded in the Victoria state perinatal data collection system. The birth studied was the first after the referral, for women who were untreated, and the first after treatment, for women who received treatment. The follow-up period for the women ranged from 2 years to 20 years after referral. The researchers report their findings in a new paper published in the BJOG: An International Journal of Obstetrics and Gynaecology. Overall, there were 533 observed preterm births in the cohort of 5,548 women, significantly higher than the 312 cases expected based on national figures. The main findings included the following: a.. The risk of preterm birth (defined as within 37 weeks of gestation) was significantly higher for both treated and untreated women compared with the general population. b.. The risk of preterm birth was significantly higher among the treated women than among the untreated women. c.. Other factors significantly associated with an increased risk of preterm birth were a history of induced or spontaneous abortion, illicit drug use during pregnancy, and a major maternal medical condition. In terms of treatment, cone biopsy, loop electrosurgical excision procedure (LEEP), and diathermy were associated with preterm birth; after adjustment for potentially confounding factors, only the association between diathermy and preterm birth remained statistically significant. d.. Women treated with laser ablation did not have a significantly increased risk of preterm birth. Discussing their findings, the researchers say the study is the largest to date examining pregnancy outcomes following diagnosis and treatment for precancerous changes in the cervix. They conclude: Women presenting with precancerous changes in the cervix are at an increased risk for preterm birth, a risk that appears to be increased by treatments that remove or destroy substantial amounts of cervical tissue. They suggest that, in light of these findings, there needs to be a re-evaluation of treatment programmes involving a see and treat policy for the management of abnormal Pap smear results. In addition, the use of ablative techniques such as laser ablation need revisiting, the researchers state.
RE: [ozmidwifery] Article about preterm birth and treatment for cervical changes
Hi Jayne It's actually a new - socalled revolutionary vaccine - against cervical changes. I do not not know that much about the actual compund yet - vague press info so far, but they do stress making it universal for all girls at onset of puberty and before sexual beginning, thus 15 years of age. Here, it's sold as an option for these girls without parental consent. So many issues, that just scream concern without/before further knowledge. We're in the midst of complete governmental change these days, so actions like this, is really possible to push through without any notice going on. Best regards, Kirsten in Denmark -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of jayne/jesse Sent: 11. januar 2007 02:33 To: ozmidwifery@acegraphics.com.au Subject: Re: [ozmidwifery] Article about preterm birth and treatment for cervical changes Hi Kirsten, Are you talking about the HPV (genital warts) vaccine? They say HPV is responsible for approx 70% of cervical cancer cases although I have seen that figure stretched beyond the 70% for the sake of advertising of the HPV vaccine. I'm not sure where the figure comes from. I would say money figures heavily on the agenda :) The vaccine is now available in Australia and the US. I'm not sure where else at present. Regards Jayne - Original Message - From: Kirsten mailto:[EMAIL PROTECTED] Lerstrøm To: ozmidwifery@acegraphics.com.au Sent: Thursday, January 11, 2007 10:19 AM Subject: RE: [ozmidwifery] Article about preterm birth and treatment for cervical changes Dear all Twice in one night out of two years I feel compelled to answer posts on the list! This study has been used as a propellar for inaugerating new studies performed on the pregnant here in Denmark! Actually they claim to have a vaccine given to young girls up to 15 years old, that would solve this problem. I have great dificulties getting totally convinced a vaccine could solve this particular cancer problem. And this at a moment where the National Health Institute finally has acknowledged major problems with screening of breast cancer and the like (a.o. Down's Syndrome), because of poor results as to positive/negative readings followed by distress due to trauma caused by the readings. What is really the agenda? Kirsten in Denmark -Original Message- From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Helen and Graham Sent: 10. januar 2007 23:04 To: ozmidwifery Subject: [ozmidwifery] Article about preterm birth and treatment for cervical changes Precancerous changes and preterm births Issue 01: 8 Jan 2007 Source: BJOG: An International Journal of Obstetrics and Gynaecology 2007;114:70-80 A study has provided new insights into the association between precancerous changes in the cervix and the risk of subsequent preterm birth. The findings suggest that diagnosis of precancerous changes, regardless of the treatment given, is associated with a significantly increased risk of delivery before 37 weeks gestation. Researchers at centers in Carlton, Australia, conducted a retrospective cohort study, investigating the records of 5,548 women who: 1. Were referred to a cervical dysplasia clinic at the Royal Womens Hospital in Carlton between 1982 and 2000 for assessment of an abnormality detected on a routine Pap smear or for evaluation of a cervix that appeared abnormal; and 2. Subsequently had a birth recorded in the Victoria state perinatal data collection system. The birth studied was the first after the referral, for women who were untreated, and the first after treatment, for women who received treatment. The follow-up period for the women ranged from 2 years to 20 years after referral. The researchers report their findings in a new paper published in the BJOG: An International Journal of Obstetrics and Gynaecology. Overall, there were 533 observed preterm births in the cohort of 5,548 women, significantly higher than the 312 cases expected based on national figures. The main findings included the following: * The risk of preterm birth (defined as within 37 weeks of gestation) was significantly higher for both treated and untreated women compared with the general population. * The risk of preterm birth was significantly higher among the treated women than among the untreated women. * Other factors significantly associated with an increased risk of preterm birth were a history of induced or spontaneous abortion, illicit drug use during pregnancy, and a major maternal medical condition. In terms of treatment, cone biopsy, loop electrosurgical excision procedure (LEEP), and diathermy were associated with preterm birth; after adjustment for potentially confounding factors, only the association between diathermy and preterm birth remained statistically significant. * Women treated with laser ablation did not have a significantly increased risk of preterm birth
