Re: [Bioc-devel] Missing CHM13v2.0 TxDB and OrgDb objects

2023-12-10 Thread Vincent Carey
Good question.  I believe these will be forthcoming soon.  In the mean time
you can
create your own.  See, for example

https://github.com/vjcitn/BiocT2T/blob/devel/inst/scripts/makeTxDb.R

It's an active area so you can pull a gff file from
https://s3-us-west-2.amazonaws.com/human-pangenomics/index.html?prefix=T2T/CHM13/assemblies/annotation/
and adjust the code noted above for the TxDb.

For the org.db I have to get back to you.

On Sun, Dec 10, 2023 at 12:06 PM Christian Arnold via Bioc-devel <
bioc-devel@r-project.org> wrote:

> Hello, I am working with the new human T2T-CHM13v2.0  assembly and while
> a BSgenome package already exists
> (BSgenome.Hsapiens.NCBI.T2T.CHM13v2.0), I could not find the
> corresponding TxDb and OrgDb packages. Is there any information when
> they may also become available so it is easier to work with the new
> genome for packages like ArchR, which support a custom genome but need
> these standard annotation packages for their creation?
>
>
> Thanks a lot for any information regarding this!
>
> Best, Christian
>
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>

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[Bioc-devel] Missing CHM13v2.0 TxDB and OrgDb objects

2023-12-10 Thread Christian Arnold via Bioc-devel

Hello, I am working with the new human T2T-CHM13v2.0  assembly and while
a BSgenome package already exists
(BSgenome.Hsapiens.NCBI.T2T.CHM13v2.0), I could not find the
corresponding TxDb and OrgDb packages. Is there any information when
they may also become available so it is easier to work with the new
genome for packages like ArchR, which support a custom genome but need
these standard annotation packages for their creation?


Thanks a lot for any information regarding this!

Best, Christian

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[Rd] capabilities() could report strict-barrier

2023-12-10 Thread Jan Gorecki
Hi,

I would like to propose for capabilities() function to include information
about strict-barrier (--enable-strict-barrier flag).
I can now do "grep barrier /usr/local/lib/R/etc/Makeconf" but having that
in R, in platform independent way, would be useful.

Best Regards,
Jan Gorecki

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