Thanks, I had totally missed this controversy but from quick read of summary
the impact on open source analysis was unclear.Can you explain the punchline? I
think many users of R have concluded the biggest problem in most analyses
isfirst getting the data and then verfiying any results you derive, both issues
that sound related to your post.
( The jumble below is illustrative of what hotmail has been doing with plain
text, getting plain data withoutall the formatting junk is a recurring problem
LOL).
#62; Date#58; Mon, 26 Mar 2012 22#58;38#58;56 #43;0100#13;#10;#62;
From#58; iaingallagher#64;btopenworld.com#13;#10;#62; To#58;
gunter.berton#64;gene.com#59; r-help#64;r-project.org#13;#10;#62;
Subject#58; Re#58; #91;R#93; Completely Off Topic#58;Link to IOM report on
use of #34;-omics#34; tests in clinical trials#13;#10;#62;#13;#10;#62;
I followed this case while it was
ongoing.#13;#10;#62;#13;#10;#62;#13;#10;#62; It was a very interesting
example of basic mistakes but also #40;for me#41; of journal
politicking.#13;#10;#62;#13;#10;#62;#13;#10;#62; Keith Baggerly and
Kevin Coombes wrote a great paper - #34;DERIVING CHEMOSENSITIVITY FROM CELL
LINES#58; FORENSIC BIOINFORMATICS AND REPRODUCIBLE RESEARCH IN HIGH-THROUGHPUT
BIOLOGY#34; in The Annals of Applied Statistics #40;2009, Vol. 3, No. 4,
1309#8211;1334#41; which explains some of the background and investigative
work they had to do to bring those mistakes to light.!
#13;#10;#62;#13;#10;#62;#13;#10;#62;
Best#13;#10;#62;#13;#10;#62;
iain#13;#10;#62;#13;#10;#62;#13;#10;#62;#13;#10;#62; - Original
Message -#13;#10;#62; From#58; Bert Gunter
#60;gunter.berton#64;gene.com#62;#13;#10;#62; To#58;
r-help#64;r-project.org#13;#10;#62; Cc#58;#13;#10;#62; Sent#58;
Monday, 26 March 2012, 19#58;12#13;#10;#62; Subject#58; #91;R#93;
Completely Off Topic#58;Link to IOM report on use of #34;-omics#34; tests in
clinical trials#13;#10;#62;#13;#10;#62; Warning#58; This has little
directly to do with R, although R and related#13;#10;#62; tools #40;e.g.
sweave and other reproducible research tools#41; have a#13;#10;#62; natural
role to play.#13;#10;#62;#13;#10;#62; The IOM
report#58;#13;#10;#62;#13;#10;#62;
http#58;//www.iom.edu/Reports/2012/Evolution-of-Translational-Omics.aspx#13;#10;#62;#13;#10;#62;
that arose out of the Duke Univ. genomics testing scandal ha!
s been#13;#10;#62; released. My thanks to Keith Baggerly for forwar
ding this. I believe#13;#10;#62; that many R users in the medical research
community will find this#13;#10;#62; interesting, and I hope I do not
venture too far out of line by#13;#10;#62; passing on the link to readers of
this list. It #42;#42;will#42;#42; have an#13;#10;#62; important impact
on so-called Personalized Health Care #40;which I guess#13;#10;#62; affects
all of us#41;, and open source analytical #40;statistical#41;#13;#10;#62;
methodology is a central issue.#13;#10;#62;#13;#10;#62; For those
interested, try the summary first.#13;#10;#62;#13;#10;#62; Best to
all,#13;#10;#62; Bert#13;#10;#62;#13;#10;#62;#13;#10;#62;
--#13;#10;#62;#13;#10;#62; Bert Gunter#13;#10;#62; Genentech
Nonclinical Biostatistics#13;#10;#62;#13;#10;#62; Internal Contact
Info#58;#13;#10;#62; Phone#58; 467-7374#13;#10;#62;
Website#58;#13;#10;#62;
http#58;//pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pd!
b-biostatistics/pdb-ncb-home.htm#13;#10;#62;#13;#10;#62;
__#13;#10;#62;
R-help#64;r-project.org mailing list#13;#10;#62;
https#58;//stat.ethz.ch/mailman/listinfo/r-help#13;#10;#62; PLEASE do read
the posting guide
http#58;//www.R-project.org/posting-guide.html#13;#10;#62; and provide
commented, minimal, self-contained, reproducible
code.#13;#10;#62;#13;#10;#62;#13;#10;#62;
__#13;#10;#62;
R-help#64;r-project.org mailing list#13;#10;#62;
https#58;//stat.ethz.ch/mailman/listinfo/r-help#13;#10;#62; PLEASE do read
the posting guide
http#58;//www.R-project.org/posting-guide.html#13;#10;#62; and provide
commented, minimal, self-contained, reproducible code.#13;#10;
__
R-help@r-project.org mailing list
https://stat.ethz.ch/mailman/listinfo/r-help
PLEASE do read the posting guide http://www.R-project.org/posting-guide.html
and provide commented, minimal, self-contained, reproducible code.
