Hi,
  I am new to R and I need to solve the following problem: I have an ODE model 
with variables x(t) and y(t) that can be solved using the deSolve package. That 
model uses several parameters. Now I have a set of observations for y(t), 
denoted as Y(t). I need to optimize the value of these parameters such that 
error between the model output y(t) and the observation Y(t) is minimized. In 
another word, y(t) is fitted to Y(t) as much as possible. What R package is 
available to optimize these parameter? Is there any sample R codes available?  
Thank you very much for your help!

Jiefeng

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