[R] Mean survival times

2005-11-17 Thread Christoph Scherber
Dear list,

I have data on insect survival in different cages; these have the 
following structure:

  deathtime status id cageS  F G   L S
1.5  1  1 C1  8  2 1   1 1
1.5  1  2 C1  8  2 1   1 1
   11.5  1  3 C1  8  2 1   1 1
   11.5  1  4 C1  8  2 1   1 1

There are 81 cages and each 20 individuals whose survival was followed 
over time. The columns S,F,G,L and S are experimentally manipulated 
factors thought to have an influence on survival.

Using survfit(Surv(deathtime,status)~cage) gives me the survivorship 
curves for every cage. But what I´d like to have is a mean survivorship 
value for every cage.

Obviously, using tapply (deathtime,cage,mean) gives me mean values, but 
I´d like to have a better estimate of this using a proper statistical 
model. I´ve tried a glm with poisson errors (as suggested in Crawley´s 
book, page 628), but the back-transformed estimates (using status as the 
response variable and deathtime as an offset) were totally unrealistic.

As I´m new to survival analysis, it would be great if anyone could give 
me some hints on what method would be best.

Thanks a lot!
Christoph

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Re: [R] Mean survival times

2005-11-17 Thread Göran Broström
On 11/17/05, Christoph Scherber [EMAIL PROTECTED] wrote:
 Dear list,

 I have data on insect survival in different cages; these have the
 following structure:

   deathtime status id cageS  F G   L S
 1.5  1  1 C1  8  2 1   1 1
 1.5  1  2 C1  8  2 1   1 1
11.5  1  3 C1  8  2 1   1 1
11.5  1  4 C1  8  2 1   1 1

 There are 81 cages and each 20 individuals whose survival was followed
 over time. The columns S,F,G,L and S are experimentally manipulated
 factors thought to have an influence on survival.

 Using survfit(Surv(deathtime,status)~cage) gives me the survivorship
 curves for every cage. But what I´d like to have is a mean survivorship
 value for every cage.

 Obviously, using tapply (deathtime,cage,mean) gives me mean values, but
 I´d like to have a better estimate of this using a proper statistical
 model. I´ve tried a glm with poisson errors (as suggested in Crawley´s
 book, page 628), but the back-transformed estimates (using status as the
 response variable and deathtime as an offset) were totally unrealistic.

 As I´m new to survival analysis, it would be great if anyone could give
 me some hints on what method would be best.

No method is best, but some methods may be useful ;) One such may be
to fit a parametric model to your data. Check 'survreg'.

Göran

 Thanks a lot!
 Christoph

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--
Göran Broström

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