Re: [R] sas vs. R

2004-11-21 Thread Marc Schwartz
On Sun, 2004-11-21 at 09:15 -0800, [EMAIL PROTECTED]
wrote:
 I wish some of the corporations or 
 universities that are using SAS would fund the R group a little, too.

We do via the R Foundation!

http://www.r-project.org/nosvn/foundation/memberlist.html

Talk to the folks at your institutions...

Marc Schwartz
No longer a SAS user

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Re: [R] sas vs r

2004-04-28 Thread Göran Broström
On Wed, Apr 28, 2004 at 11:13:30AM +0200, Henric Nilsson wrote:
 At 05:24 2004-04-28, Liliana Forzani wrote:
 
 I have a code in sas (NLMIXED) and I have a hard time converting to r
 1)it is poisson, with random intercept, but
 it have an offset.  Means, I do not want one of the coefficient to be
 estimate. Means, may model is
 g(mean) = beta X + Z,
 Z fixed, X fixed and beta to be estimate
 I am using glmmML.
 
 If I recall correctly, neither glmmML nor glmmPQL (from MASS) handles 
 offset terms. But GLMM in the lme4 package does.

glmmML handles offset terms. I am pretty sure that glmmPQL does too.

 
 2) the same but I have random slope (and I think with glmmML I can use
 only random intercept)
 
 GLMM in lme4 can do this.
 
 3) I try to use nlme, is this equivalent to NLMIXED?
 
 No, nlme fits non-linear and linear mixed-effect models with Gaussian error 
 terms.
 
 I hope this helps,
 Henric
 
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Re: [R] sas vs r

2004-04-28 Thread Henric Nilsson
At 11:39 2004-04-28, Göran Broström wrote:
 If I recall correctly, neither glmmML nor glmmPQL (from MASS) handles
 offset terms. But GLMM in the lme4 package does.
glmmML handles offset terms.
You're right. I confused it with glmmML's not being able to fit models with 
family = gaussian. Sorry.

 I am pretty sure that glmmPQL does too.
glmmPQL doesn't complain about the offset term but ignores it. I guess that 
glmmPQL ignores offsets since lme, upon which glmmPQL depends, ignores offsets.

//Henric
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RE: [R] sas vs. r

2003-06-06 Thread Marc Schwartz
-Original Message-
From: [EMAIL PROTECTED] 
[mailto:[EMAIL PROTECTED] On Behalf Of wensui liu
Sent: Friday, June 06, 2003 1:16 PM
To: [EMAIL PROTECTED]
Subject: [R] sas vs. r


I like R more than SAS. My job is doing research on clinical 
trial. But I was told that FDA only accepts the result from 
SAS. Is that true? TOO BAD.


See these recent posts by Frank Harrell:

http://maths.newcastle.edu.au/~rking/R/help/03a/4210.html

http://maths.newcastle.edu.au/~rking/R/help/03a/4231.html

http://maths.newcastle.edu.au/~rking/R/help/03a/4246.html


HTH,

Marc Schwartz

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Re: [R] sas vs. r

2003-06-06 Thread Spencer Graves
	  Please check http://www.r-project.org/; - search - R site 
search.  My search just now for R vs. SAS for FDA produced 14 matches.

	  My bottom line from reading comments on this issue is that it is like 
the comment 20 years ago that, Nobody in management ever got fired for 
buying IBM.  The r-help archives include comments that FDA has no 
specific guidelines for what software must be used, although there are 
doubtless general guidelines relating to documentation and testing that 
it does what it claims.

hth.  spencer graves

wensui liu wrote:
I like R more than SAS. My job is doing research on clinical trial. But I was told that FDA only accepts the result from SAS. Is that true? TOO BAD.



	[[alternate HTML version deleted]]

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Re: [R] sas vs. r

2003-06-06 Thread Thomas Lumley
On Fri, 6 Jun 2003, wensui liu wrote:

 I like R more than SAS. My job is doing research on clinical trial. But
 I was told that FDA only accepts the result from SAS. Is that true? TOO
 BAD.


No, it isn't true.  The FDA does not approve or certify statistical
software. Its main regulation relevant to statistical analysis is in 21
CFR 11, and is largely about audit trails.  In fact the FDA is very
reluctant to issue blanket approval or disapproval for anything -- it
likes to keep its options open.


On the other hand, if a company has been successful in getting FDA
approval with analyses done one way, there is a substantial incentive not
to change. Why take the risk that it might slow down the approval of your
application?


-thomas

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Re: [R] sas vs. r

2003-06-06 Thread A.J. Rossini
wensui liu [EMAIL PROTECTED] writes:

 I like R more than SAS. My job is doing research on clinical
 trial. But I was told that FDA only accepts the result from SAS. Is
 that true? TOO BAD.

No.  But it's not that simple.

See previous postings (within the last 2 months) on validation and
FDA. 

best,
-tony

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A.J. Rossini  /  [EMAIL PROTECTED]  /  [EMAIL PROTECTED]
Biomedical/Health Informatics and Biostatistics, University of Washington.
Biostatistics, HVTN/SCHARP, Fred Hutchinson Cancer Research Center.
FHCRC: 206-667-7025 (fax=4812)|Voicemail is pretty sketchy/use Email 

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