RE:[tips] Electroshock Therapy For, Uh, Well ....

2015-05-22 Thread Wuensch, Karl L
This procedure uses sound waves, not electrical shocks.

Cheers,

Karl L. Wuensch


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RE:[tips] Electroshock Therapy For, Uh, Well ....

2015-05-22 Thread Mike Palij
On Fri, 22 May 2015 12:56:16 -0700, Karl L Wuensch wrote: 

   This procedure uses sound waves, not electrical shocks.


But that's not funny. ;-)

And when you get around to later posts, you'll see that I
acknowledge that it is not electric shocks but sound waves
and suggested some things guys could do with stereo
speakers. ;-)


Cheers,
Karl L. Wuensch


Have a good weekend and memorial day.

-Mike Palij
New York University
m...@nyu.edu


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[tips] Electroshock Therapy For, Uh, Well ....

2015-05-21 Thread Mike Palij

The following is a brief article about a presentation made
at the Annual Meeting of the American Urological Association
(AUA) on May 20, 2015; see:
http://www.firstwordpharma.com/node/1285407?tsid=1#axzz3amtebZZT
Guys, this article is either good news or wince inducing. Or both.
Gals, this article might suggest one way to spice up
your next sexual encounter (say you're doing research) ;-).

Although I was shocked by this treatment, it turns out that it 
really isn't new as this 2013 abstract from PubMed shows:

http://www.ncbi.nlm.nih.gov/pubmed/23554844

Please do not suggest to your students that they should attempt 
to replicate this study. ;-)


-Mike Palij
New York University
m...@nyu.edu


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Re: [tips] Electroshock Therapy For, Uh, Well ....

2015-05-21 Thread Carol DeVolder
At the risk of being insensitive, how would one go about conducting the
sham portion of the study? Certainly not double-blind, but could there be a
blind group in this case? Wouldn't that tend to confound it?
cd


On Thu, May 21, 2015 at 10:41 AM, Mike Palij m...@nyu.edu wrote:

 The following is a brief article about a presentation made
 at the Annual Meeting of the American Urological Association
 (AUA) on May 20, 2015; see:
 http://www.firstwordpharma.com/node/1285407?tsid=1#axzz3amtebZZT
 Guys, this article is either good news or wince inducing. Or both.
 Gals, this article might suggest one way to spice up
 your next sexual encounter (say you're doing research) ;-).

 Although I was shocked by this treatment, it turns out that it really
 isn't new as this 2013 abstract from PubMed shows:
 http://www.ncbi.nlm.nih.gov/pubmed/23554844

 Please do not suggest to your students that they should attempt to
 replicate this study. ;-)

 -Mike Palij
 New York University
 m...@nyu.edu


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-- 
Carol DeVolder, Ph.D.
Professor of Psychology
St. Ambrose University
518 West Locust Street
Davenport, Iowa  52803
563-333-6482

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Re: [tips] Electroshock Therapy For, Uh, Well ....

2015-05-21 Thread Mike Palij

On Thu, 21 May 2015 09:04:47 -0700, Carol DeVolder wrote:

At the risk of being insensitive, how would one go about
conducting the sham portion of the study? Certainly not
double-blind, but could there be a blind group in this case?
Wouldn't that tend to confound it?


A couple of points in response:

(1) The abstract on PubMed links to the free research article;
see upper right hand corner of page at:
http://www.ncbi.nlm.nih.gov/pubmed/23554844
You can get more details from there if you have not already
obtained the article.

(2) I quote from the article the following paragraph which
describes what they did:

|The encouraging results from these two studies led us to
|conduct a prospective, randomized, double-blind,
|sham-controlled study on 60 men with ED [Vardi et al. 2012].
|In this study, we investigated the effects of LI-ESWT on
|erectile function and penile blood flow using the identical
|treatment protocol and study parameters that were used in
|our previous two studies. For the sham-treatment, we used
|a probe which did not produce any SW energy but looked
|identical to the treatment probe and produced the same
|noise and feeling of a 'hit'.

NOTE #1: By hit I assume that it is a sensation like the treatment
but not the treatment itself.
NOTE #2: Okay, I exaggerated a bit: the treatment is not electroshock
but Low Intensity Extracoporeal Shockwave Therapy (LI-ESWT)
and the shockwaves are acoustic waves. As the author say:
When LI-ESWT is applied to an organ, the relatively weak
yet focused SWs interact with the targeted deep tissues where
they cause mechanical stress and microtrauma. This stress and
microtrauma (also known as shear stress) induces a cascade
of biological reactions that result in the release of angiogenic
factors which in turn triggers neovascularization of the tissue
with subsequent improvement of the blood supply.  I imagine
one could simulate the effect by putting one's crotch on a high
output audio speaker.

Continuing the quote:

|The demographic characteristics and the baseline mean IIEF-EF
|scores of the treated and sham-treated patients of this third study
|were similar. We found that mean IIEF-EF domain scores of the
|treated men were significantly higher than those of the sham-treated
|men. This increase in the IIEF-EF domain scores was also
|accompanied by improvements in cavernosal blood flows and penile
|endothelial function, as measured by venous occlusion plethysmography
|of the penis (FMD). We have been following most of these men
|for more than 2 years and they all report that the beneficial response
|that was achieved immediately after therapy has not waned (Table 1).
(Page 98)

I will leave it to someone else to explain exactly how the sham
treatment is done.

(3) This is my 3rd post to Tips today so no more from me today. 
[APPLAUSE!!!]

I have to play around with my stereo speakers. ;-)

-Mike Palij
New York University
m...@nyu.edu


On Thu, May 21, 2015 at 10:41 AM, Mike Palij m...@nyu.edu wrote:

The following is a brief article about a presentation made
at the Annual Meeting of the American Urological Association
(AUA) on May 20, 2015; see:
http://www.firstwordpharma.com/node/1285407?tsid=1#axzz3amtebZZT
Guys, this article is either good news or wince inducing. Or both.
Gals, this article might suggest one way to spice up
your next sexual encounter (say you're doing research) ;-).

Although I was shocked by this treatment, it turns out that it really
isn't new as this 2013 abstract from PubMed shows:
http://www.ncbi.nlm.nih.gov/pubmed/23554844

Please do not suggest to your students that they should attempt to
replicate this study. ;-) 



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