Is there a performance benefit for using one way rather than the other? This stemmed from a problem I encountered with cross domain scripting and I've been weighing the pros and cons against panels and pages.
On the negative side I need a new page hierarchy since I can't reuse the original layout inside a much smaller window. It also means different css and js files, and some css components can't be shared unless they are broken out of the master.css. On the positive side I can add analytics to the pages and track them better. I'm not sure if the iframe is a benefit or not. A final concern is in the case of an error, if I am using iframes I don't want the standard error page to fill the frame since it uses my original layout which would look strange, I'd rather have the whole page redirect to an error. Can anyone share info about what they had done or how you ended up one way or the other?